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Mutations & Pedigrees

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Which of the following is NOT a cause of mutations?

a)

Mistakes made during meiosis

b)

Mistakes made during protein synthesis

c)

Viruses

d)

Bacteria

2.

Which type of mutations happen during DNA replication?

a)

Gene Mutations

b)

Nondisjunction

c)

Translocation

d)

Chromosome Mutations

3.

An insertion or deletion of a nucleotide is an example of a...

a)

Frameshift Mutation

b)

Point Mutation

c)

Chromosome Mutation

d)

Nondisjunction

4.

AAG to CAG is an example of a...

a)

Point Mutation

b)

Frameshift Mutation

c)

Nondisjunction

d)

Duplication

5.

Which of the following is NOT a chromosome mutation?

a)

Nondisjunction

b)

Duplication

c)

Translocation

d)

Relocation

6.

In which type of mutation do chromosomes fail to separate correctly during anaphase?

a)

Nondisjunction

b)

Translocation

c)

Gene Mutations

d)

Duplication

7.

Which type of mutation changes the size of a chromosome?

a)

Insertion

b)

Deletion

c)

Substitution

d)

Duplication

8.

Down syndrome (Trisomy 21) is an example of...

a)

Nondisjunction

b)

Duplication

c)

Translocation

d)

Gene Mutation

9.

What would be the genotype of an affected individual with an autosomal recessive disorder?

a)

AA

b)

Aa

c)

aa

d)

XaY

10.

Which of the following genotypes could be a carrier?

a)

Tt

b)

TT

c)

tt

d)

XTY

11.

How is Huntington's Disease different than other autosomal dominant disorders?

a)

It is caused by two (2) dominant alleles

b)

It can have carriers

c)

It appears early in life

d)

It usually does not appear until adulthood

12.

Why are males more likely to have sex-linked disorders?

a)

Males have one (1) Y chromosome

b)

Males have two (2) X chromosomes

c)

Males have dominant chromosomes

d)

Males only have one (1) X chromosome

13.

In which sex chromosome disorder do males have extra X chromosome(s).

a)

Down Syndrome

b)

Turner's Syndrome

c)

Muscular Dystrophy

d)

Klinefelter's Syndrome

14.

What is a pedigree?

a)

A chart used to trace a disease or trait

b)

A genetic map of an individual's DNA

c)

A sex-linked recessive disorder

d)

An autosomal dominant disorder

15.

Which of the following statements about autosomal recessive disorders is TRUE?

a)

They are the most common pattern of inheritance

b)

Disease is common in the family

c)

Males are more likely to inherit the disease

d)

Disease will never skip a generation

16.

This is an example of which pattern of inheritance?

a)

Autosomal Dominant

b)

Autosomal Recessive

c)

Sex-Linked

d)

Autosomal Chromosomal

17.

Which statement about autosomal dominant disorders is FALSE?

a)

Disease will have many affected family members

b)

Disease will often skip a generation

c)

Males and Females are equally likely to inherit the disease

d)

A child cannot inherit the disease from two (2) healthy parents

18.

Which pattern of inheritance is shown?

a)

Autosomal Dominant

b)

Autosomal Recessive

c)

Sex-Linked

d)

Sex-Chromosome

19.

Which statement about Sex-Linked Recessive disorders is TRUE?

a)

Disease is common in the family

b)

Disease will never skip a generation

c)

Affected fathers will NEVER pass the disease on to their sons

d)

Females are more likely to inherit the disease than males

20.

Which pattern of inheritance is this?

a)

Autosomal Dominant

b)

Autosomal Recessive

c)

Sex-Linked

d)

Sex- Chromosome