NEW
Font size
WorksheetsUnit-II Pharmacodynamic
Total questions: 15
Worksheet time: 11mins
Grey baby syndrome occurs with which of the following drugs?
Doxycycline
Penicillin
Clarithromycin
Chloramphenicol
Which of the following is the main danger caused by acetaminophen (Paracetamol, Tylenol) overdose?
Cardiac failure
Hepatic failure
Renal failure
Brain damage
What is informed consent in a clinical trial?
Signed document of the recruited patient for the clinical trial procedures
Patients injected with placebo and active doses
The subjects do not know which study treatment they receive
Fake treatment
Which of the trial phase is for pharmacovigilance?
Phase II
Phase IV
Phase I
Phase III
What is the full form of IND?
Under Investigation
Investigated drug
Investigation Application
Investigation of New Drug Application
Doses are expressed on a _________ basis.
Time of administration
Body-weight
Precision
Accuracy
The LD50 refers to:
the lethal dose in 50 people taking the drug.
the lethal dose in 50% of the population taking the drug.
the labeled dosage recommended for the drug.
the labeled dose for at least 50 people taking the drug.
When two drugs act on the same receptor the resulting drug interaction is said to be which of the following
Synergistic
Unpredictable
Predictable
Additive
What is the term"Potentiation" mean?
Hypersensitivity of drug
Intensive Increase in drug effect due to combination
Fast tolerance developing
All of the above
An undesirable effect of a drug that
occurs at therapeutic doses and can be
predicted from its pharmacological
actions is called
Side effect
Toxic effect
Idiosyncrasy
Allergic reaction
The therapeutic index of a drug is a
measure of its
Dose variability
Efficacy
Potency
Safety
Which of the following statements
regarding therapeutic window is correct?
The ratio of LD50 to the ED50
The Dosage range between the minimum
effective therapeutic concentration and the
minimum toxic concentration
Both the above
None of the above
When the same dose of a drug is repeated at half-life intervals, the steady-state plasma drug concentration is reached after:
2-3 half-lives
4-5 half-lives
6-7 half-lives
8-10 half-lives
Factors that may cause variation in drug responsiveness:
Changes in the number or function of receptors
Idiosyncratic drug responses
Hypersensitivity reactions
All of the above
Which type of reaction occurs in between Antacid and Ketoconazole
Alters the GI Motility
Alters the pH
Alters the bacterial flora
Displaces protein binding
