WorksheetsTUBERCULOSIS UPDATES- FINAL ROUND
Total questions: 20
Worksheet time: 10mins
Nucleic acid amplification -NAA tests for the diagnosis of TB
Are not approved by the FDA
Require more than one month for results
May not be used with smear positive specimens
Are able to differentiate between different species for M.tuberculosis
What test do you suggest when a PLHIV smear is negative but the chest X-ray is suggestive of tuberculosis
CBNAAT
Mantoux test
IGRA
All of the above
The dosing of ATT drugs are given below-
1. INH 5mg/kg
2. Rifampicin 15mg/kg
3. Ethambutol 10mg/kg
4. Pyrazinamide 20mg/kg
choose the right answer
1,2,3,4
2,3
1,3,4
1,4
MDR TB is defined as resistance to-
More than 3 antitubercular drugs
Isoniazid, rifampicin and pyrazinamide
Isoniazid and rifampicin
Fluoroquinolones and atleast one of the three injectable second line drugs used to treat TB
Which of the following is used for diagnosing drug resistant tuberculosis-
Sputum smear microscopy
Liquid culture
Chest X-ray
Interferon gamma release assay
The cardinal symptoms of tuberculosis are all of the follwing except-
Blood in sputum
Shortness of breath
Cough with expectoration
Weight gain
The average time of exposure to someone with active TB until acquisition of infection is about-
2 hours
2 days
2 weeks
2 months
The usual cause for secondary or reactivation TB is a breakdown of the patients-
Immune system
Digestive system
Circulatory system
Integumentary system
Groups that are considered high risk for contracting TB who should be screened include HIV infected persons, injecting drugs, and
All hospital workers
Close contacts with Tb positive patients
Persons with healthy immune system
Residents in area with severe air pollution
2 first line ATT drugs used in the treatment of drug susceptible TB-
Rifabutin and streptomycin
Rifabutin and capreomycin
Ethambutol and levofloxacin
Isoniazid and rifampin
The scientist who discovered MTB-
Louis Pasteur
Robert Koch
Jean Antoine Villemin
Calmette and Guerin
Which of the following diagnostic tests is intended for latent tuberculosis infection-
Sputum smear microscopy
Polymerase chain reaction
Interferon gamma release assay
ELISA for TB antibodies
IGRA and Mantoux skin test cannot distinguish between latent infection and active disease. True or false
True
False
LPA detects-
Rifampicin resistance
Rifampicin and INH
Second line of drugs
All of the above
Who discovered PCR-
Kary B Mullis
Barbara Mc Clintock
Ernst Ruska
None of the above
Who discovered Acid fast staining-
Paul Ehrlich
Ziehl Neelson
Robert Koch
None of the above
India is committed to eliminate tuberculosis from the year-
2025
2030
2035
2045
What is the percentage of risk for people with TB infection and diabetes over a lifetime-
10 percent
25 percent
30 percent
40 percent
In accordance with the NTEP (National Tuberculosis Elimination Programme) 2020 guidelines, the newborn whose mother has active tuberculosis and is on ATT, should be ruled out for active TB. Then the neonate should be managed with prophylactic isoniazid (INH) for 6 months, BCG vaccination at birth, with the continuation of breastfeeding.
True
False
What is polydrug resistance-
Resistant to more than one 1st line anti-TB drug, other than Rifampicin.
Resistant to a fluoroquinolone (ofloxacin, levofloxacin, or moxifloxacin) and a second-line injectable anti TB drug (kanamycin, amikacin, or capreomycin)
Resistant to both isoniazid and rifampicin
None of the above
