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Worksheets

2

Total questions: 50

Worksheet time: 2hrs 40mins

Name
Class
Date
1.

The amino and carboxyl groups of amino acids are bonded to which carbon?

a)

a. Both are bonded to the α-carbon.

b)

b. Both are bonded to the β-carbon

c)

c. The amino is bonded to the α-carbon, and the carboxyl is bonded to the β-carbon

d)

d. The amino is bonded to the β-carbon, and the carboxyl is bonded to the α-carbon

2.

Which amino acid has the three-letter symbol asn?

a)

a. aspartic acid

b)

b. asparagine

c)

c. alanine

d)

d. arginine

3.

Which is a correct pair of abbreviations for an amino acid?

a)

a. Gln / N

b)

b. Tyr / T

c)

c. Asn / N

d)

d. Phe / P

e)

e. Pro / Q

4.

Which amino acid is classified as polar?

a)

a. L

b)

b. H

c)

c. P

d)

d. I

5.

Which of the following amino acids has a side chain that can make hydrogen bonds to other molecules?

a)

a. Leu

b)

b. Ser

c)

c. Ala

d)

d. Gly

6.

Which amino acids contain sulfur?

a)

a. cysteine and lysine

b)

b. cysteine and methionine

c)

c. arginine and methionine

d)

d. cysteine and isoleucine

7.

Which of the following is not considered an uncommon amino acid?

a)

a. thyroxine

b)

b. Hydroxylysine

c)

c. Hydroxyproline

d)

d. Tryptophan

8.

which of the following pairs of bonds within a peptide back bone show free rotation around both bonds

a)

a. C=O and N-Cα

b)

b. C=O and N-C

c)

c. Cα-C and N-Cα

d)

d. N-C and Cα-C

9.

which of the following factor involve in folding of protein back bone

a)

a. Hydrophopic character of amino acids

b)

b. Free rotation around peptide bond

c)

c. Lack of rotation around peptide bond

d)

d. Hydrophilic character of amino acids

10.

Type of bonds between C terminal and N terminal

a)

a. Covalent

b)

b. disulphide bond

c)

c. peptide

d)

d. Ionic

e)

e. Both a&c

11.

Cystein is a sulfur containing amino acids and can form a ……………………

a)

a. Hydrigen bond

b)

b. N bond

c)

c. S-S bond

d)

d. K bpnd

12.

Which of the following statements is true?

a)

a. All triacylglycerols and all phosphoacylglycerols have the same fatty acids in them.

b)

b. All triacylglycerols have the same fatty acids, but the fatty acids in phosphoacylglycerols vary.

c)

c. The fatty acids in triacylglycerols vary, but all phosphoacylglycerols have the same fatty acids in them.

d)

d. The fatty acids in both triacylglycerols and in phosphoacylglycerols vary.

13.

Which of the following groups is not present in a phosphatidic acid?

a)

a. Choline

b)

b. Fatty acids

c)

c. Glycerol

d)

d. Phosphate

e)

e. All of these are components of phosphatidic acid

14.

Saponification is the hydrolysis of a(n)

a)

a. peptide bond

b)

b. ester bond

c)

c. anhydride bond

d)

d. glycosidic bond

15.

Glycolipids are characterized by containing the following non-lipid component:

a)

a. Sugars

b)

b. Glycerol

c)

c. Phosphate

d)

d. Sphingosine

e)

e. More than one of these characterize glycolipids

16.

Which of the following four fatty acids has the highest melting point?

a)

1. CH3CH2CH2CH2CH2COOH

b)

2. CH3CH2CH2CH2CH2CH2CH2CH 2CH2COOH

c)

3. CH3CH2CH2CH2CH2CH2CH2COOH

d)

4. CH3CH=CHCH2CH2COOH

17.

Fatty acids with multiple double bonds are usually conjugated.

a)

a. True

b)

b. False

18.

Which of the following four fatty acids has the lowest melting point?

a)

1. CH3CH2CH2CH2CH2COOH

b)

2. CH3CH2CH2CH2CH2CH2CH2CH 2CH2COOH

c)

3. CH3CH2CH2CH2CH2CH2CH2COOH

d)

4. CH3CH=CHCH2CH2COOH

19.

which of the following is not true for cholesterol?

a)

a. cholesterol soulble in chloroform

b)

b.it contains four fused ring system

c)

c.it founds in cell membranes of prokaryotes

d)

d. cholesterol in membranes can modify role of membrane bound proteins

20.

Lipase catalyzed hydrolysis of 4 molecules of triacylglycerols would

produce:

a)

a. 12 glycerols & 4 RCOO-

b)

b. 4 Glycerols & 3 RCOO

c)

C. 1 glycerols & 3 RCOO-

d)

d. 4 Glycerols & 12 RCOO-

21.

which of the following characteristics, fatty acids have?

a)

a. A hydrophilic molecule with cis double bond and unbranched hydrocarbon chain

b)

b. an amphipathic molecule with cis double bond and branched hydrocarbon chain

c)

c. an amphipathic molecule with conjugated double bond

d)

d. an amphipathic molecule which is monoprotic

22.

Mcdonald burger contains 2g fat ,complete oxidation of this produce ……….energy

a)

a. 18 Kcal

b)

b. 4 Kcal

c)

c. 8 Kcal

d)

d. 9 Kcal

23.

18:2 for a fatty acid means:

a)

a. saturated with 16- carbon atom.

b)

b. saturated with 18- carbon atom.

c)

c. unsaturated with two double bonds.

d)

d. unsaturated with one double bonds.

24.

Cephalin contains

a)

a. 1 glycerols, 3 fatty acid, phosphate group and ethanolamine

b)

b. 1 glycerols, 3 fatty acid, phosphate group and serine

c)

c. 1 glycerols, 1 fatty acid, 2 phosphate group and serine

d)

d. 1 glycerols, 2 fatty acid, phosphate group and ethanolamine

25.

which of the following is not product of saponification:

a)

a.potassium salt of fatty acids

b)

b. sodium salt of fatty acids

c)

c. precipitate of fatty acids with magnesium

d)

d. glycerol

26.

The nucleotide sequence of DNA is which level of structure?

a)

a. primary

b)

b. secondary

c)

c. tertiary

d)

d. quaternary

27.

What distinguishes nucleotides from nucleosides?

a)

a. Nucleosides lack the phosphate group.

b)

b. Nucleosides lack the sugar group.

c)

c. Nucleosides lack a nitrogenous base.

d)

d. The two words are synonymous

28.

Which of the following is the most common modification of nucleic acid bases?

a)

a. addition of a methyl group

b)

b. addition of a carboxylic acid

c)

c. addition of a fluorine

d)

d. reduction of a carbonyl to an alcohol

29.

Deoxythymidylate (dT) is a:

a)

a. purine base

b)

b. pyrimidine base

c)

c. pyrimidine based nucleotide

d)

d. purine based nucleotide

e)

e. nucleoside

30.

The backbone of nucleic acids consists of

a)

a. a phosphodiester bond between the 2' and 5' hydroxyl groups of neighboring sugars

b)

b. a phosphodiester bond between the 3' and 5' hydroxyl groups of neighboring sugars

c)

c. a glycosidic bond between a pyrimidine and a sugar

d)

d. a glycosidic bond between a purine and a sugar

31.

The oligonucleotide AGGUCCAUUGAAp, is best described as

a)

a. an RNA oligonucleotide with a 3'phosphate

b)

b. an RNA oligonucleotide with a 5'phosphate

c)

c. a DNA oligonucleotide with a 3'phosphate

d)

d. a DNA oligonucleotide with a 5'phosphate

32.

Where can drugs or polypeptides bind to DNA?

a)

a. The minor groove only.

b)

b. The major groove only.

c)

c. Either the minor or major groove.

d)

d. Neither the minor or major groove.

33.

Histones are proteins that

a)

a. are frequently associated with eukaryotic DNA

b)

b. are frequently associated with prokaryotic DNA

c)

c. are never found in association with DNA

d)

d. contain a high percentage of residues with carboxylic acid side chains

e)

e. None of these

34.

one strand of DNA is 5’ CTG GTA CTG AGC 3’ its complementary strand would be ………………….

a)

a. 3’ GAC CAT GAC TCG 5’

b)

b. 5’ GAC CAU GAC UCG 3’

c)

c. 3’ GAC CAU GAC UCG 5’

d)

d. 5’ GAC CAT GAC TCG 3’

35.

dpG signifies which of following information

a)

a. its 5’ nucleotide having ribose sugar and guanine nitrogenous base

b)

b. its nucleoside having deoxy ribose sugar and guanine nitrogenous base

c)

c. its 5’ nucleotide having deoxy ribose sugar and guanine nitrogenous base

d)

d. its 3’ nucleotide having deoxy ribose sugar and guanine nitrogenous base

36.

Purines bases form a glycosidic linkage with the sugar at:

a)

a. N-1 nitrogen

b)

b. N-2 nitrogen

c)

c. N-9 nitrogen

d)

d. None of these

37.

which of the following scientists have contributions towards finding the structure of DNA ?

a)

a. James Watson and Francis Crick

b)

b. Rosalind Franklin and Maurice Wilkins

c)

c. Erwin chargaff

d)

d. All of them

38.

Epimers are

a)

a. stereoisomers that differ from each other in their configuration at two or more carbon atoms.

b)

b. stereoisomers that differ from each other in their configuration at a single carbon atom.

c)

c. the α and β forms of cyclic sugars.

d)

d. two related compounds, pyran and furan.

39.

For the α anomer of a D-sugar, the anomeric hydroxyl in a Haworth projection

a)

a. has an upward projection (on the same side as the terminal CH2OH group).

b)

b. has a downward projection (on the opposite side from the terminal CH2OH group)

c)

c. may be either up or down, it depends on the individual sugar.

d)

d. is non-existent; anomers are a consideration only in Fischer projections.

40.

In a Fischer projection, which chiral carbon determines whether the sugar is the D- or the L-isomer?

a)

a. highest numbered carbon atom

b)

b. lowest numbered asymmetric carbon atom

c)

c. lowest numbered carbon atom

d)

d. highest numbered asymmetric carbon atom

41.

Mirror image stereoisomers are called

a)

a. anomers.

b)

b. diastereoisomers.

c)

c. enantiomers.

d)

d. epimers.

42.

Diastereomers are

a)

a. mirror-image, nonsuperimposable stereoisomers.

b)

b. non-mirror-image, nonsuperimposable stereoisomers.

c)

c. stereoisomers with one or more double bonds.

d)

d. none of the above

43.

How many enantiomeric pairs are possible for a aldohexose?

a)

a. 2

b)

b. 4

c)

c. 8

d)

d. 16

44.

The cyclic form of sugars

a)

a. has one more chiral center (the anomeric carbon) than the open-chain form.

b)

b. loses a chiral center compared to the open-chain form.

c)

c. is not usually found in nature.

d)

d. has one more carbon atom than the open-chain form.

e)

e. has one less carbon atom than the open-chain form.

45.

Which carbon of the open-chain form of a sugar becomes the anomeric carbon in the cyclic form?

a)

a. the carbonyl carbon

b)

b. the highest numbered chiral center

c)

c. the highest numbered carbon

d)

d. It depends on the individual sugar.

46.

A pyranose is a sugar that

a)

a. contains a five-membered ring as part of its cyclic structure.

b)

b. contains a six-membered ring as part of its cyclic structure.

c)

c. is a five-carbon open-chain sugar.

d)

d. is a six-carbon open-chain sugar.

47.

For a D-sugar, any group that is written to the right of the carbon in a Fischer projection

a)

a. has an upward projection in a Haworth projection.

b)

b. has a downward projection in a Haworth projection.

c)

c. may be either up or down in a Haworth projection, it depends on the individual sugar.

d)

d. is missing from a Haworth projection.

48.

Which of the following groups is produced when an aldehyde is oxidized?

a)

a. ketone

b)

b. carboxyl

c)

c. alcohol

d)

d. ether

49.

A lactone is a cyclic

a)

a. ether.

b)

b. ester.

c)

c. ketone.

d)

d. alcohol

50.

The conversion of a sugar's carbonyl to an alcohol is

a)

a. a reduction reaction.

b)

b. an oxidation reaction.

c)

c. a glycosidic reaction.

d)

d. impossible