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A 5 DNA and Modern Genetics

Total questions: 40

Worksheet time: 21mins

Name
Class
Date
1.

Which molecule provides the blueprint for making proteins in an organism?

a)

DNA

b)

Amino Acids

c)

Enzymes

d)

Codons

2.

If human DNA is composed of approximately 30% Thymine, how much Guanine is likely present?

a)

10%

b)

20%

c)

30%

d)

60%

3.

If a strand of DNA is comprised of 17% adenine, how much thymine will be present?

a)

17%

b)

34%

c)

42%

d)

83%

4.

If a strand of DNA is comprised of 28% thymine, how much cytosine will be present?

a)

14%

b)

22%

c)

28%

d)

36%

5.

If Cytosine and Guanine make up a total of 36% of a strand of DNA, how much Adenine will be present?

a)

18%

b)

32%

c)

36%

d)

64%

6.

The backbone of DNA is made up of

a)

deoxyribose sugar, nitrogen bases, phosphate

b)

nitrogen bases, phosphate

c)

deoxyribose sugar, phosphate

d)

deoxyribose sugar, nitrogen bases

7.

The rungs of DNA are made up of

a)

nitrogen bases, phosphate

b)

deoxyribose sugar, phosphate

c)

deoxyribose sugar, nitrogen bases

d)

nitrogen bases

8.

A nucleotide consists of

a)

bases and a phosphate

b)

base and a sugar

c)

phosphate and a sugar

d)

sugar, phosphate and a base

9.

What nitrogen bases are in DNA?

a)

adenine, thymine, guanine, cytosine

b)

adenine, uracil, guanine, cytosine

c)

adenine, thymine, uracil, cytosine

d)

adenine, thymine, guanine, uracil

10.

Which best describes the job of DNA?

a)

Provides instructions for assembling protein molecules.

b)

Provides instructions for assembling chromosomes into histones.

c)

Helps with shuffling amino acids into proteins.

d)

Helps with relocating mRNA into physical traits.

11.

For what does the information in our genes provide the instructions?

a)

assembling protein molecules

b)

assembling chromosomes into DNA

c)

rearranging RNA into proteins

d)

rearranging DNA into physical traits

12.

If a stand of DNA read 3’ -CGC|TTG|AAG|CGA-5’ what would be the code for the complementary strand?

a)

6’-GCG|AAC|TTC|GCT-1’

b)

5’-GCG|AAC|TTC|GCT-3’

c)

5’-GCG|AAA|CTT|GCG|T-3’

d)

5’-CGC|TTG|AAG|CGA-3’

13.

In the diagram below, strands I and II represent the two complementary strands of a portion of a DNA double helix. The sequence of strand I is indicated below. What is the sequence of strand II? Strand I -----------C-T-A-C----------- Strand II -----------?-?-?-?-------------

a)

AGCA

b)

CTAC

c)

TCGT

d)

GATG

14.

Within which structure of an animal cell does DNA replication take place?

a)

Vacuole

b)

Cell membrane

c)

Nucleus

d)

Ribosome

15.

Molecules involved in replication (Select all that apply).

a)

DNA

b)

mRNA

c)

tRNA

d)

rRNA

16.

What nitrogen bases are in RNA?

a)

Adenine, thymine, guanine, and cytosine

b)

Adenine, uracil, guanine, and cytosine

c)

Adenine, thymine, uracil, and cytosine

d)

Adenine, thymine, guanine, and uracil

17.

Which statement best describes RNA?

a)

RNA is usually double stranded and contains the base thymine

b)

RNA is usually single stranded and contains the base uracil

c)

RNA is longer than DNA and uses 5 bases to encode information

d)

RNA is made in the nucleus and stays there to carry out its function

18.

Which of the following is not a type of RNA?

a)

tRNA

b)

mRNA

c)

rRNA

d)

dRNA

19.

The process by which the genetic code of DNA is copied into a strand of mRNA is called

a)

Translation

b)

Transformation

c)

Transcription

d)

Replication

20.

Molecules involved in transcription (Select all that apply).

a)

DNA

b)

mRNA

c)

tRNA

d)

rRNA

21.

Transcribe the DNA strand into mRNA. Section it into codons. Translate it into amino acids. TAC GGC CGA TGC ATT.

a)

AUG CCG GCU ACG UAA → Met - Pro - Ala - Thr - STOP

b)

AAC CCG CGA AGC AAA → Iso - Pro - Arg - Ser - Lys

c)

UAC GGC GCA UGC AUU →Tyr - Gly - Ala - Cys - Iso

d)

AUC CCG CGA UGC UUU → Iso - Pro - Arg - Cys - Phe

22.

Molecules involved in translation (Select all that apply).

a)

DNA

b)

mRNA

c)

tRNA

d)

rRNA

23.

Which of the following codons signifies the end of translation?

a)

GAC

b)

GGG

c)

UGA

d)

UGC

24.

How many nucleotides are needed to code for one amino acid?

a)

1

b)

3

c)

6

d)

12

25.

If a strand of mRNA is 492 nucleotides long, how many amino acids will be in the protein it creates?

a)

164

b)

246

c)

984

d)

1,476

26.

If a protein is 386 amino acids long, how many nucleotides created it?

a)

128

b)

193

c)

772

d)

1,158

27.

DNA Polymerase reads the original strand from the _ end of the DNA molecule towards the _ end.

a)

3’ to 5’

b)

5’ to 3’

28.

During DNA replication, newly formed DNA is built starting at the _ end and moving towards the _ end.

a)

3’ to 5’

b)

5’ to 3’

29.

The lagging strand of the newly synthesized DNA goes _ the replication fork.

a)

away from

b)

towards

30.

The leading strand of the newly synthesized DNA goes _ the replication fork.

a)

away from

b)

towards

31.

separate the hydrogen bonds between nitrogen bases to unzip DNA molecule

a)

DNA helicase

b)

DNA Polymerase

c)

Okazaki

32.

read the template strand of DNA and add new nucleotides accordingly

a)

DNA helicase

b)

DNA Polymerase

c)

Okazaki

33.

Lagging DNA is built using _ fragments

a)

DNA helicase

b)

DNA Polymerase

c)

Okazaki

34.

Mutations that only affect one single nucleotide.

a)

Chromosomal Mutation

b)

Frameshift mutation

c)

Gene Mutation

d)

Point Mutation

e)

Silent Mutation

35.

A gene mutation that results in no change in the amino acid sequence.

a)

Chromosomal Mutation

b)

Frameshift mutation

c)

Gene Mutation

d)

Point Mutation

e)

Silent Mutation

36.

Mutations that affect one gene.

a)

Chromosomal Mutation

b)

Frameshift mutation

c)

Gene Mutation

d)

Point Mutation

e)

Silent Mutation

37.

Mutations that affect multiple genes.

a)

Chromosomal Mutation

b)

Frameshift mutation

c)

Gene Mutation

d)

Point Mutation

e)

Silent Mutation

38.

A gene mutation that affects multiple nucleotides.

a)

Chromosomal Mutation

b)

Frameshift mutation

c)

Gene Mutation

d)

Point Mutation

e)

Silent Mutation

39.

Select the gene mutations.

a)

Deletion - Insertion - Substitution

b)

Duplication - Inversion - Translocation

c)

Deletion - Duplication - Translocation

d)

Duplication - Inversion - Substitution

e)

Deletion - Insertion - Translocation

40.

Select the chromosomal mutations

a)

Deletion - Insertion - Substitution

b)

Duplication - Inversion - Translocation

c)

Deletion - Duplication - Translocation

d)

Duplication - Inversion - Substitution

e)

Deletion - Insertion - Translocation