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WorksheetsDiuretics and Nitric Oxide
Total questions: 10
Worksheet time: 8mins
Identify the drugs acting at this site
Carbonic anhydrase Inhibitors
Loop diuretics
Thiazide diuretics
Potassium sparing diuretics
4 mechanisms of Sodium transport in Proximal tubule
Direct entry Of Na along a favorable electrochemical gradient
Transport of Na and K coupled to active reabsorption of glucose, amino acids, other organic anions and PO4 through specific symporters
Na-H antiporter moves H from tubular fluid to inside the cell
Other anion reabsorption takes Na and water along to maintain electrical neutrality and isotonicity
Na-H antiporter moves Na from tubular fluid to inside the cell
Mannitol is a (a) diuretic
Uses of these diuretics
Edema
Hypotension
Diabetes insipidus
Hyperuricemia
Hypercalciuria
Drug interactions
Decreases Plasma digoxin concentration
Hypokalemia can occur along with ACE inhibitors
can produce dangerous hyperkalemia when given along with potassium supplements
Aspirin attenuates action of spirinolactone
Uses
Bedwetting in children
Hemophilia
Diabetes Insipidus
Renal concentration test
Constrictor of visceral and vascular smooth muscles
Prevents platelet aggregation
Neurotransmitter in brain and periphery
No role in inflammatory diseases and septic shock
Dilates arterioles and veins by
Release of NO
Guanylyl cyclase activation
All of the above
None of the above
Example of Dual Endothelin Receptor Antagonists
(a)
Icatibant is a
(a)
