Which of the following drug can result in teratogenic effect shown in the diagram if given during pregnancy?

Despite their short half-lives (2 hrs), proton pump inhibitors (PPIs) cause a prolonged suppression of acid secretion (up to 48 h) because:

Methysergide which was once used as a drug of choice for prophylaxis of migraine is not used nowadays because of risk of

Which of the following diuretics cause hypercalcemia and can be used in recurrent renal calcium stones?

For which of the following type of patients, the device shown in image should be used for delivering the drug?

A patient diagnosed as having ventilator associated pueumonia,is on treatment with ceftriaxone and amikacin. Culture and sensitivity turned out to be positive for ESBL producing klebsiella infection. The most appropriate next action should be:

A bank employee,felt depressed with no interest in activities,came to AIIMS OPD. He was started on escitalopram. Which of these adverse effects cannot be explained with escitalopram ?

A 30 year old female was treated with an antihypertensive drug and presented with the following features. The likely drug was:

A patient with cancer developed extreme degree of radiation toxicity. Further history revealed that the dose adjustment of a particular drug was missed during the course of radiotherapy. Which of the following drugs required a dose adjustment during radiotherapy in order to prevent radiation toxicity?

A drug have half life of 12 hours is administered orally twice a day. A graph is plotted between plasma drug concentration and time which is shown in the graph. How much time will be taken for the plasma concentration to reach at point A

A 70-kg young athlete was planned for surgery. During anaesthesia, vecuronium was not available, so repeated doses of succinylcholine was given intermittently up to 640 mg. During recovery, patient was not able to spontaneously respire and move limbs. What is the cause?

An 18 month old child with ambiguous genitalia presented to the hospital, his BP is 118/78 mm Hg, serum K is 6mEq/L, serum sodium is 120 mEq/L. Patient was started on intravenous fluids. What additional specific therapy will you add?

A 50-year-old male, suffering from renal failure,underwent kidney transplant. He was prescribed a nucleotide derivative of therapeutic importance in this organ transplant is:

A patient presented to emergency with overdose of some drug. There was increased bronchial secretions. On examination, blood pressure was 88/60 mm Hg. RBC esterase level is 50. What should be the treatment of this person?

A bacterium was isolated from the central nervous system of a newborn that died of meningitis. The vagina of the mother was colonized with the same isolate as determined by the capsular antigen. The microbe grew well on standard blood and MacConkey agar at ambient atmospheric conditions. What is the most likely etiologic agent?

During a medical camp, an infant with failure to thrive is evaluated. The mother indicates that the child has a poor appetite and is resistant to breast feeding. A white pseudomembranous coating seen in the child’s mouth is shown in the photograph. A scraping of the material, observed under the microscope, is also shown. Which antimicrobial is the most appropriate treatment for this condition?

A 2-month-old infant presents with severe pyoderma over much of her body. Her history is signifi cant for other infections including pneumonia and for bruising very easily. Both parents are healthy with no signifi cant medical history. Physical exam reveals an ill infant with large areas of hypopigmentation of the skin, silvery hair, and very pale eyes. Gingival inflammation and bleeding of the gums and generalized lymphadenopathy are noted. A white blood cell count reveals moderate leukopenia and thrombocytopenia. Defi nitive diagnosis is made by examination of a peripheral blood smear which showed unusually large granules within neutrophils and eosinophils. What is the most likely diagnosis?

A Peace Corps agricultural advisor, who is stationed on an island in the eastern Indian Ocean, becomes ill with headache, fever, and respiratory symptoms. At the local clinic, a prominent eschar on the abdomen just below the beltline is detected. Local physicians easily make a clinical diagnosis of an illness carried by rodents and transmitted by mites. Doxycycline therapy is empirically administered and the patient makes an uneventful recovery. What is the name of the illness and the etiologic agent?

Following an initial expansion of B cells in response to microbial peptides, a memory pool of B cells is generated and maintained in the individual in many cases throughout life. Recently, it was discovered that two memory cell types were generated in response to microbial challenge. Upon rechallenge with the microbe, the patient is protected from infection. Which one of the following explanations accounts for this observation?

Two weeks after visiting a construction site in Ohio that was a former poultry farm, a 56-year-old Florida man with chronic myelogenous leukemia presents with fever of 39 °C and difficulty breathing. The illness began with flu like symptoms and progressed to nonproductive cough and dyspnea. A chest radiograph reveals diffuse pulmonary infiltrates and mediastinal lymphadenopathy. Results of a needle biopsy of lung tissue stained with methamine silver are shown in the accompanying photograph. What is the etiology of this man’s disease?

During a medical mission to tropical Latin America, a woman presents with a chronic infection of her foot as seen in the accompanying photograph. Secretions from the lesions, upon Gram staining, clearly reveal the presence of fi lamentous Gram-positive cells.Which bacterial species is descriptive of the offending agent?

During the summer in western Massachusetts, a teenager complains of aching muscles and joints and mild fever. He notices a rash on the side of his upper leg (shown in the photograph), which prompts his mother to take him to the clinic. What is the most likely etiology and route of transmission?

A 23-year-old woman comes to the hospital due to fever, chills, dyspnea, and cough for the past several days. She also has sharp right-sided chest pain exacerbated by breathing. Her temperature is 39 C (102 F), blood pressure is 115/70 mm Hg, and pulse is 108 min. On examination, the patient has several needle track marks on both arms. There is a 3/6 holosystolic murmur heard best at the lower sternal border that increases on inspiration. Chest imaging reveals scattered bilateral peripheral lung opacities. HIV testing is negative.Which of the following could be the causative agent?

You are a microbiologist working in a lab and observe the following on a blood agar plate . Which of the following will not be an etiologic agent?

You are an intern Posted in the post natal ward of hospital. You recieved a HIV positive patient on PND-1. Which of the following tests would you use to detect HIV in the baby?

In which of the following situations will you use sanitizer?

1) After examining the patient.

2) Before examining the patient.

3) After touching the patient's surroundings.

4) Hands are visibly soiled.

A 55 yr old man comes with a complaint of fever and increasing fatigue for the past one week. On examination he is febrile, hypotensive and tachycardic. The findings in peripheral blood smear on microscopic examination is shown below. Which of the following can be the Causative agent?

A 24 yr old male patient came with complaints of diarrhea, vomiting and abdominal pain for past one week. The stool microscopy revealed the following. What is the appropriate treatment for this condition?

Which of the following is not used to detect Covid 19 infection ?

A 25 years old female has abdominal pain, fatigue, weight loss, diarrhea. From stool examination diagnosis of hookworm infestation was made. If we do CBC what parameters can be seen?

A 55 year old female patient having large adenexal mass with raised inhibin level. Histopathology shows cord and sheets of tumor cell, often showing nuclear groove as shown in the Image, based on above clinical features identify the type of tumor

Deepak 51-yrs-old presents with rapidly progressive dementia and dies. At autopsy, marked spongiform degeneration of the brain is found. Which of the following is the basic cause of this disorder?

The swelling of size 1.5cm is seen over chest of 20 year old, soft to firm reddish swelling progressing in size. Histopathological examination showed the following. What could be your possible diagnosis

A surgeon suspecting testicular carcinoma in a patient asks the intern to send the sample for histopathology, what is the fluid in which the intern should send the sample to the pathologist?

A 25 years old female came to OPD 1year after postpartum. She was treated for iron deficiency anemia while pregnancy. Now she is pale and her HB was 5% and reticulocyte count was 9%. Her corrected retic count is?

A 56 years old chronic smoker, mass in bronchus resected. What is the possible marker to confirm diagnosis?

A patient with diffuse enlargement of thyroid gland showed the following histopathological picture. Which of the following statements is false about the condition?

Patient with severe bleeding comes to emergency dept. As per your demand you get 4 platelet and 2 PRC units from blood bank. What should be the next step

A male patient with history of bleeding was investigated and was found to have increased APTT but normal PT. His maternal uncle had a similar presentation. The next step of investigation should be

A 11 years old boy has elevated prothrombin and activated partial prothrombin time. What is the most likely defect?

Pedigree analysis- analyze the following Pedigree and give the mode of inheritance

Dystrophic calcification is/are found in?

A 21-year-old boy, who is known case of asthma, presents to your office with wheezing and rhinitis. Laboratory results show peripheral eosinophilia and antibodies against neutrophil myeloperoxidase. What is the most likely diagnosis?

A resected specimen of the kidney is shown in the image below. What is your diagnosis?