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Reproductive Medicine Quiz HTA Conference Day1

Total questions: 12

Worksheet time: 11mins

Name
Class
Date
1.

A 34 year old, woman attends the infertility clinic with her husband. She has been trying to conceive for the last 2 years. Her periods were normal until 2 years ago which is why she was started on combined oral contraceptive pills. She has stopped them for 6 months now. Her body mass index is 35, general and pelvic examinations are normal. What investigation should be requested next?

a)

Blood test to measure luteinizing hormone, follicle stimulating hormone, sex hormone binding globulin, testosterone, prolactin and thyroid function

b)

Hysterosalpingogram

c)

Pelvic ultrasound

d)

17 hydroxyprogesterone

e)

Semen analysis

2.

A 31 year old, woman and her partner are attending the infertility clinic because she has been trying to conceive for the last 2 years despite regular unprotected sexual intercourse. She had a normal vaginal delivery 10 years ago with the same partner. The woman has no past medical history and is not taking any medications. Her BMI is 23 and her periods are regular. The results of blood test, ultrasound and hysterosalpingography, and Semen analysis are normal. What management would you advise?

a)

Clomiphene citrate for 12 months

b)

Clomiphene citrate for 6 months

c)

Can continue unprotected intercourse for 12 months

d)

Intrauterine fertilization

e)

IVF

3.

Which of the following statements are correct?

a)

FSH is normal or mildly elevated in premature ovarian insufficiency.

b)

FSH is markedly elevated in early ovarian ageing.

c)

Individuals with early ovarian ageing are usually asymptomatic.

d)

Individuals with premature ovarian insufficiency do not need oestrogen replacement.

4.

Measures to predict ovarian response to gonadotrophin stimulation in IVF are all except?

a)

Antral follicle count less than 4.

b)

Antral follicle count more than 16.

c)

Anti-Mullerian hormone.

d)

FSH level.

e)

Ovarian volume.

5.

Which ONE of the following clinical scenarios is considered diagnostic of polycystic ovarian syndrome?

a)

Infrequent periods, elevated testosterone.

b)

Infrequent periods, infertility, low day 21 serum progesterone.

c)

Infrequent periods, impaired glucose tolerance, obesity.

d)

Polycystic ovaries, obesity, low day 21 serum progesterone.

e)

Polycystic ovaries, elevated LH:FSH ratio, obesity.

6.

Who first coined the term Onco-fertility back in 2006?

a)

Andreson

b)

Teresa K. Woodruff

c)

Jose V Medrano

d)

Letouneau

7.

Which class of chemotherapy agents is best known for their gonadal toxicity and associated infertility/sterility?

a)

Alkylating agents.

b)

Methotrexate.

c)

Bleomycin.

d)

Actinomycin.

8.

A 32 year old, female treated at age 15 for Hodgkin lymphoma with chemotherapy without radiation, arrives at your clinic and wants to discuss a fertility workup. She has attempted pregnancy for 9 months without success. Who would you ideally refer her to?

a)

Haematologist.

b)

Reproductive Medicine Specialist.

c)

Oncologist.

d)

Psychiatrist.

9.

What percentage of infertility cases are caused by male infertility?

a)

20%

b)

40%

c)

50%

d)

60%

10.

What percentage of all men are affected by male infertility?

a)

5%

b)

7%

c)

13%

d)

15%

11.

What is the cause of 50% of male infertility?

a)

Cystic Fibrosis.

b)

Abnormal karyotyping.

c)

Smoking.

d)

Unexplained.

12.

The following modifiable risk factors are linked to male infertility EXCEPT?

a)

Obesity.

b)

Low-fat diary product diet.

c)

Cigarette smoking.

d)

Stress.