WorksheetsEntresto BPI Quiz
Total questions: 20
Worksheet time: 12mins
Following oral administration, sacubitril-valsartan dissociates into sacubitril which is further metabolized into (a) and valsartan?
The color of Entresto 50mg tablet:
Pale Yellow
Light Pink
Violet White
White
The color of Entresto 200mg tablet:
Pale Yellow
Light Pink
Violet White
Purple
100mg Entresto is equivalent to:
50 mg Sac and 50 mg Val
46 mg Sac and 54 mg Val
48.6 mg Sac and 51.4 mg Val
47.7 mg Sac and 52.3 mg Val
The recommended starting dose of Entresto is (a) except in certain situations.
What is the target dose of Entresto?
50 mg BID
100 mg BID
200 mg OD
200 mg BID
Treatment of Entresto can be initiated in patients with serum potassium level <5.4 mmol/l?
True
False
Treatment with Entresto can be initiated in the following except:
SBP >= 100 mmHg
Patients who stopped using ACEi for 36 hours
Patients using direct renin inhibitor
Patients with serum Potassium level of <5.4 mmol/l
What is the considered Entresto starting dose for patients with SBP >= 100 mmHg to 110 mmHg?
50 mg BID
100 mg BID
200 mg BID
100 mg OD
50 mg OD
Should Entresto be initiated on patients with SBP <100 mmHg?
Yes, but with caution.
No.
Yes, Use 50 mg OD
It depends on the situation.
What is the recommended dose for Entresto in patients with moderate renal impairment?
50 mg OD
50 mg BID
100 mg BID
100 mg OD
What is the recommended dose for Entresto in patients with moderate hepatic impairment?
No dose adjustment is required.
100 mg OD
50 mg BID
100 mg BID
Use of Entresto may be associated with decrease renal function.
True
False
Sometimes
Not really.
Angioedema has been reported in patients treated with Entresto.
No.
Yes.
Maybe.
Never.
I don't know.
Caution should be exercised when initiating Entresto to NYHA IV patients due to limited clinical experience in this population.
True.
False.
Co-administration with furosemide influenced the pharmacokinetics of Entresto.
True.
False.
Entresto can be initiated during pregnancy. True or False.
(a)
A single dose of Entresto 1200 mg and multiple doses of 900 mg were studied in healthy volunteers and were not well tolerated. True or False.
(a)
Co-administration of Entresto with metformin both reduced the Cmax and AUC of metformin.
True
False
Entresto inhibits or induces CYP450 enzymes.
True
False
