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WorksheetsPharmaceutical Suspensions
Total questions: 10
Worksheet time: 16mins
Which of the following is not a typical requirement for lotions?
Must dry quickly
Must be fluid, not highly viscous
Must have a smooth feel to the skin
Must be sweet
Which of the following phenomena is undesirable in pharmaceutical suspension?
Slow settling of particles
Particles readily redisperse upon agitation
Particles agglomerate to dense cake
Suspension pours readily
Which of the following statements are true regarding pharmaceutical suspension for oral administration?
Suspensions for oral administration may require the addition of sweetening agents.
Suspensions for oral administration may require the addition of flavours.
The pH of the continuous phase may affect the stability of aqueous suspensions designed for oral administration.
The particle size of dispersed drug in pharmaceutical suspensions designed for oral administration must be <10 µm.
Which of the following statements are correct regarding DLVO theory?
The zeta potential acts as a repulsion barrier.
Particles residing within the primary minimum produce pharmaceutically acceptable suspensions.
Alteration of the magnitude of the secondary minimum may be performed by increasing the concentration of electrolyte.
Increasing the concentration of hydrophilic polymer in a suspension increases the stability of the suspension by increasing the magnitude of the primary maximum.
What does the symbol η represent in Stoke’s equation?
Particle diameter
Particle density
Medium density
Medium viscosity
Based on Stoke’s equation, which property of a particle in a suspension formulation could you increase to make the particles sediment at a slower rate?
Particle diameter
Gravity
Viscosity of the medium
Particle density
For a drug particle in a suspension-based dosage form, the edge of shear plane of the electrical double layer is measuring the _____________________.
Nernst potential
Zeta potential
Stern potential
Shear potential
Choose the correct statements.
Flocculation is desirable for pharmaceutical suspensions.
Deflocculation is not desirable for pharmaceutical suspensions.
Motion of dispersed particles in a suspension is induced by thermal and gravitational forces.
Viscosity of the suspension affects the settling of particles
Crystal growth of particles in a suspension is due to temperature fluctuation on storage and due to wider particle size distribution.
Flocculated suspensions exhibit the following properties
A low sedimentation volume
A high degree of flocculation
A high rate of sedimentation
Homogeneity of drug concentration per unit dose
Which of the following ingredients in a suspension could help in flocculating the dispersed particles?
Surfactant
Hydrophilic polymer
Electrolyte
Cosolvent
