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Lecture 4 - Cholinergic Drugs

Total questions: 15

Worksheet time: 4hrs 31mins

Name
Class
Date
1.

Which one of the following drugs are used to help smokers to stop cigarettes

a)

Cevimeline

b)

Bethanechol

c)

Varenicline

d)

Neostigmine

2.

Acetylcholine is an accessible drug that is present in several dosage forms (oral, injection or patches) in the pharmacy

a)

Yes

b)

No

3.

If an ophthalmologist wants to treat glaucoma, shall he use

a)

Cholinergic agonists

b)

Cholinergic antagonists

c)

Mydriatic drops

d)

Sympathomimetic drug

4.

If a patient suffering from post-operative urine retention asks your advise about his prescription, you approved the choice of his physician as he prescribed to him

a)

Malathion

b)

Bethanechol

c)

Pralidoxime

d)

Acetylcholine

5.

Among the synthesis of acetylcholine, it can act on a cholinergic presynaptic receptor that can regulate its release by negative feedback mechanism

a)

M2

b)

Nm

c)

M1

d)

Nn

6.

The acronym SLUD represents the adverse effects of cholinomimetic drugs means

a)

Sedation, low blood pressure, urination, delirium

b)

Sleepiness, lacrimation, uterine contractions, defecation

c)

Salivation, lacrimation, urination, diarrhea

d)

Salivation, lacrimation, urination, dehydration

7.

The vasodialatory effect of Ach is due to

a)

Alfa-1 agonist effect

b)

M1 agonist effect

c)

Parasympathetic nerve supplying blood vessels

d)

Extrajunctional M3 activation

8.

Cholinergic drugs cause a change in the heart rate represented by

a)

Positive inotropic

b)

Positive chronotropic

c)

Negative chronotropic

d)

Negative dromotropic

9.

The following drug can improve asthma symptoms

a)

Bethanechol

b)

Pyridostigmine

c)

Atropine

d)

Pilocarpine

10.

Quaternary cholinergic drugs don't have an effect on

a)

Eye

b)

Stomach

c)

Urinary bladder

d)

CNS

11.

Pilocarpine is used in cancer patient after radiation sessions

a)

To protect against xerostomia

b)

As it decreases sweating

c)

Due to its sialagogue effect

d)

As it increases the body temperature

12.

It is the main cause of death following poisoning with organophosphorus compounds

a)

General weakness

b)

Severe diarrhea

c)

respiratory failure

d)

Intestinal cholic

13.

To treat glaucoma, you can use

a)

Muscarinic antagonist

b)

Drug that can induce ciliary muscle stimulation

c)

Drug that can induce miosis

d)

Drug that can cause mydriasis

14.

A drug of choice in treatment of Myasthenia gravis

a)

Acetylcholine

b)

Sildenafil

c)

Neostigmine

d)

Pyridostigmine

15.

Malathion is toxic because

a)

It is a competitive antagonist to cholinesterase enzyme

b)

It antagonizes cholinesterase enzyme irreversibly

c)

It is cholinesterase activator

d)

It is cholinergic drug