WorksheetsPMOC311 Antibiotic Agents
Total questions: 10
Worksheet time: 4mins
Statement 1: Position 1 in the structure of Penicillin contains Nitrogen that has no contribution to its antibacterial activity.
Statement 2: In order to alter the spectrum of activity of Penicillin, you can change the R group.
Both statements are INCORRECT.
Statement 1 is INCORRECT, but Statement 2 is CORRECT.
Both statements are CORRECT.
Statement 1 is CORRECT, but Statement 2 is INCORRECT.
Hydrophobic molecules can transverse the outer membrane through pores formed by proteins called porins.
TRUE
FALSE
Penicillin V is more acid-resistant than Penicillin G since it contains electronegative oxygen in the sidechain.
TRUE
FALSE
___________ steric hindrance alpha-carbon of the acyl group, ___________ resistance to B-lactamase
Increased, Increased
Decreased, Decreased
Increased, Decreased
Decreased, Increased
Which of the following is NOT included in the class of Aminopenicillin?
Ampicillin
Carbenicillin
Becampicillin
Hetacillin
Statement 1: Class I Beta Lactamase Inhibitors possess potent antibacterial activity in addition to its ability to cause transient inhibition of some beta lactamases.
Statement 2: Class II Beta Lactamase Inhibitors has weak antibacterial activity.
Both statements are CORRECT.
Statement 1 is CORRECT, but Statement 2 is INCORRECT.
Both statements are INCORRECT.
Statement 1 is INCORRECT, but Statement 2 is CORRECT.
Which of the following are CORRECTLY paired?
I. Ticarcillin + Clavulanic acid
II. Ampicillin + Sulbactam
III. Imipenem + Cilastatin
IV. Doxycycline + Gentamicin
II, III, and IV
I and II
I, II, III, and IV
I, II, and III
Statement 1: Neomycin is the most nephrotoxic, Streptomycin the least nephrotoxic.
Statement 2: Amikacin, Kanamycin and Neomycin may cause mainly vestibular damage.
Both statements are INCORRECT.
Statement 1 is INCORRECT, but Statement 2 is CORRECT.
Statement 1 is CORRECT, but Statement 2 is INCORRECT.
Both statements are CORRECT.
In Tetracyclines, the addition of amide at Carbon 2 reduces or abolishes its activity.
TRUE
FALSE
Which class does the given structure belongs?
Aminoglycosides
Macrolides
Lincomycins
Polypeptides
