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WorksheetsPharma 3 Mid
Total questions: 13
Worksheet time: 7mins
46-year-old man with uncomplicated stage one hypertension placed on lisinopril and
hydrochlorothiazide. After several weeks, the patient developed a dry cough. What is the
underlying cause of the cough?
Bradykinins will accumulate as an effect of lisinopril
Adverse effect
a patient with long-standing hypertension is taking (Aliskiren, amlodipine, and triamterene) what adverse affects my occur with this drug combination?
Hyperkalemia
Hypokalemia
The anti-anginal drug of choice to use in patient with visual plastic and join who has sinus bradycardia is...?
Amlodipine
Lisinopril
A patient with chronic exertional angina is refractory to combination therapy with a (beta
blocker, organic nitrate, and calcium channel blocker) which of the following drugs may be useful
in reducing the symptoms of angina in this patient?
PGE inhibitors
Ranolazine
Nitroglycerin
The mechanisms underlying the life-threatening interaction of organic nitrates and PDE5 inhibitor Is????
PGE inhibitors block the degradation of cyclic GMP in vascular smooth muscle
There is no life threatening interaction
This combination of antianginal drugs should be avoided to circumvent an adverse drug interaction????
Erapam and a B adrenergic receptor antagonist
Calcium channel blockers and nitrates
A patient is prescribed Fenofibrate as part of his therapy to increase his HDL-C levels
Fenofibrate most likely acts by???
Finding PPAR alpha receptors in liver and brown adipose tissue
Finding PPAR alpha receptors in kidney and brown adipose tissue
A patient is prescribed niacin to reduce his triglycerides and LDL- C levels
What are the side effects of niacin that patients commonly complain about???
Flushing and dyspepsia
Dizziness and dyspepsia
Flushing and dizziness
56 year old patient complains of chest pain following by sustained exercise. He is diagnosed
with atherosclerotic angina. He is prescribed sublingual nitroglycerin for treatment of acute chest pain.
Which of the following adverse effects is likely to be experienced by this patient???
Throbbing headache
Dizziness
fatigue
hypotension
56 year old patient complains of chest pain following any sustained exercise. He is diagnosed
with atherosclerotic angina. He is prescribed sub lingual nitroglycerin and propranolol (to prevent episodes)
The beta blocker (propranolol) has added benefit of preventing which of the following side effects of sub lingual nitroglycerin???
Reflex tachycardia
Hypotension
Bradycardia
68-year-old man has been successfully treated for exercise induced angina for several years. He recently has been complaining about being awakened at night with chest pain.
Which of the following drugs would be useful in preventing nocturnal angina???
Propranolol
Nitroglycerin sublingual
Which one of the following drugs increases de novo cholesterol synthesis by inhibiting the
enzyme three hydroxy three methyl glutaryl CoA reductase???
Fenofibrate
Niacin
Lovastatin
Which one of the following drugs bind bile acids in the intestine thus preventing their return to the liver via the enterohepatic circulation???
Niacine
Fenofibrate
Cholestyramine
IVIG
