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PODA 3 Dr Mo Chemo Questions for Final

Total questions: 43

Worksheet time: 32mins

Name
Class
Date
1.

WOTF following conditions is the CyVaDic regimen most likely to be employed?

a)

Oat Cell Cancer

b)

Pancreatic Cancer

c)

MDS (Myelo Dysplastic Syndrome)

d)

Soft Tissue Sarcomas

e)

Polycythemia Vera

2.

WOTF will produce its anticancer effect by inhibiting the hedgehog signaling pathway?

a)

Venetoclax (Venclexta)

b)

Blinatumomab (Blincyto)

c)

Glasdegib (Daurismo)

d)

Panobinostat (Farydak)

e)

Dexrazoxane (Zinecard)

3.

WOTF will inhibit Topoisomerase I?

a)

Camptothecins

b)

Anthracyclines

c)

Leucovorin

d)

Eculizumab (Solaris)

e)

Panobinostat (Farydak)

4.

WOTF above will inhibit BCL2 Protein?

a)

Venetoclax (Venclexta)

b)

Blinatumomab (Blincyto)

c)

Glasdegib (Daurismo)

d)

Uridine triacetate (Vistogard)

5.

WOFT will inhibit Topoisomerase 2?

a)

Venetoclax

b)

Blincyto

c)

Glasdegib

d)

Anthracyclines

e)

Solaris

6.

How does Blincyto produce its anticancer effect? What is Blincyto also referred to as? SATA

a)

Bite

b)

Targets B-cells

c)

Engages T-cells

d)

Bi-specific

7.

WOTF is an adverse effect of 5-FU?

a)

Photosensitivity and photophobia

b)

Stomatitis and enteritis

c)

Angina and MI

d)

Euphoria and malaise

8.

WOTF is a pyrimidine nucleoside that is employed in the treatment of cancer?

a)

FUDR

b)

Fluorouridine

c)

5-FU

d)

5-FC

e)

5’-deoxy-5-FU

9.

The TLT for gemcitabine is?

a)

Bone Marrow Depression

b)

Hemolytic uremic syndrome

c)

Hepatotoxicity

d)

Stomatitis

10.

A patient who is on CyVaDic will be receiving WOFT?

a)

Adriamycin

b)

Oncovin

c)

Ifosfamide

d)

Cytoxan

e)

Dacarbazine

11.

What do you use CLAG-M regimen for?

a)

Methotrexate

b)

Mitoxantrone

c)

MethylCCNU

d)

Mercaptopurine

12.

Describe the metabolism of 6-mercaptopurine

4 lines
13.

Select the correctly matched drug and adverse effect

a)

Palmar-plantar erythrodysesthesia : Capecitabine

b)

Capillary leak syndrome : Gemcitabine

c)

Acute cerebellar syndrome : Mitomycin

d)

HUS (Hemolytic uremic syndrome) : 5-FU

14.

WOTF drugs will be used to reverse or prevent HUS development?

a)

Visogard

b)

Solaris

c)

Zinecard

d)

Leucovorin

e)

Farydak

15.

WOTF combo regimens are used to treat colorectal cancer?

a)

FMiS

b)

SDF

c)

FCE

d)

FMV

e)

Folfiri

16.

WOTF is combined with Dexamethasone for the treatment of multiple myeloma?

a)

Pomalidomide

b)

Carfilzomib

c)

Daratumumab

d)

Ixazomib

e)

Thalidomide

17.

Gemcitabine is least likely to produce WOTF as an adverse effect?

a)

Hyperbilirubinemia

b)

Hyperglycemia

c)

Hypermagnesemia

d)

Hypocalcemia

e)

Hypotension

18.

WOTF Combos would you use to treat ovarian cancer?

a)

CHAD

b)

CHAP

c)

ACTH

d)

CISCA

e)

CAP

19.

WOTF is used to treat non-hodgkin’s lymphoma?

a)

FAC

b)

7+3

c)

CNOP

d)

CHOP-Bleo

e)

A-SHAP

20.

WOTF regimens are used for the treatment of ALL (Acute lymphocytic leukemia)?

a)

DVP

b)

M&M

c)

MIE

d)

Hyper CVAD A

e)

Hyper CVAD B

21.

WOTF statements about MTX (methotrexate) true?

a)

It is metabolized to 7-hydroxymethotrexate in the liver

b)

It is metabolized to mtx-polyglutamate in the liver

c)

It has a triphasic half life

d)

Food decreases its GI absorption

e)

It is administered orally and IV only

22.

What is the PPB of methotrexate?

a)

50%

b)

60%

c)

<50%

d)

>60%

23.

WOTF statements about the MOA of Malarone (Atovaquone + Proguanil) is true? It works by inhibiting:

a)

Thymidylate synthase

b)

Folic acid synthase

c)

Dihydrofolate reductase

d)

HMG co a reductase

e)

HMG Co-A Lyase

24.

Hyper CVAD B regimen consists of

a)

Vincristine

b)

Cyclophosphamide

c)

Adriamycin

d)

Dexamethasone

e)

Ara-A

25.

Hyper CVAD A regimen consists of

a)

Cyclophosphamide

b)

Vincristine

c)

Adriamycin

d)

Dexamethasone

e)

Ara-C

26.

MIE regimen consists of

a)

6-Mercaptopurine

b)

Methotrexate

c)

Mitoxantrone

d)

Ifosfamide

e)

Etoposide

27.

The M&M regimen consists of

a)

6-Mercaptopurine

b)

Methotrexate

c)

Mitoxantrone

d)

Mitomycin

28.

DVP regimen consists of

a)

Daunorubicin

b)

Vincristine

c)

Prednisone

d)

Dexamethasone

e)

Platinol

29.

A-SHAP regimen consists of

a)

Adriamycin

b)

Methylprednisolone

c)

Cytarabine

d)

Platinol

e)

Ara-C

30.

CHOP-Bleo regimen consists of

a)

Cyclophosphamide

b)

Adriamycin

c)

Oncovin

d)

Prednisone

e)

Bleomycin

31.

CNOP regimen consists of

a)

Cyclophosphamide

b)

Nitoxantron

c)

Oncovin

d)

Prednisone

e)

Cytarabine

32.

7+3 regimen for Acute Myelogenous Leukemia consists of

a)

Daunorubicin

b)

Ara-A

c)

Ara-C

d)

Doxorubicin

33.

FAC (For Breast Cancer) Regimen consists of

a)

5-Fluorouracil

b)

Adriamycin

c)

Doxorubicin

d)

Cyclophosphamide

e)

Ara-A

34.

CAP regimen consists of

a)

Cyclophosphamide

b)

Adriamycin

c)

Platinol

d)

Prednisone

e)

Ara-C

35.

CISCA Regimen consists of

a)

Cisplatin

b)

Cyclophosphamide

c)

Adriamycin

d)

Cytarabine

36.

ACTH regimen consists of

a)

Adriamycin

b)

Cyclophosphamide

c)

Taxol

d)

Herceptin

e)

Trastuzumab

37.

CHAP regimen consists of

a)

Cyclophosphamide

b)

Hexamethylmelamine

c)

Adriamycin

d)

Platinol

e)

Herceptin

38.

The CHAD and CHAP Regimens both consist of Cyclophosphamide + HMM (hexamethylmelamine) + adriamycin + platinol

a)

True

b)

False

39.

Folfiri regimen consists of

a)

Leucovorin

b)

5-fluorouracil

c)

Irinotecan

d)

Ixazomib

40.

FMV regimen consists of

a)

5-FU

b)

MethylCCNU

c)

Vincristine

d)

Cimustin

41.

FCE regimen consists of

a)

5-Fluorouracil

b)

Cisplatin

c)

Etoposide

d)

Cytoxan

42.

SDF regimen consists of

a)

Streptozotocin

b)

Doxorubicin

c)

5-Fluorouracil

d)

Dexamethasone

43.

FMiS regimen consists of

a)

5-Fluorouracil

b)

Mitomycin

c)

Streptozotocin

d)

Ara-C

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