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WorksheetsPharm Final Fall21
Total questions: 85
Worksheet time: 44mins
People taking antimicrobial drugs should be instructed to report any problem that could indicate adverse drug effects, lack of therapeutic response, or emergence of another infection. One such problem is:
skin rash.
headache.
constipation.
muscle soreness.
A female client calls the pediatrician’s office because her child reports a sore throat. The nurse anticipates the pediatrician will take what action?
Order an antibiotic.
Order an antitussive.
Request a list of drug allergies.
Request a throat culture.
What occurs when the normal flora is destroyed by the use of anti-infectives?
neurotoxicity
hypersensitivity
superinfection
resistance
Bacitracin (Baciguent) interferes with the cell wall synthesis of which type of bacteria?
Proteus
Streptococcal
Staphylococcal
Pseudomonas
What intervention is most important for the nurse to perform before antibiotic therapy is initiated?
increasing the client’s fluid intake
educating the client about adverse effects
administer an antidiarrheal to prevent gastrointestinal (GI) upset
obtaining a specimen for culture and sensitivity
A client has been diagnosed with an infection. The nurse can help to ensure the success of anti-infective treatment by:
confirming that the medication prescribed is the drug of choice for the specific microorganism.
teaching the client that significant adverse effects are expected, and must be endured during treatment.
administering antihistamines, as ordered, to prevent the development of adverse effects.
monitoring the client closely for signs of arrhythmias or cardiac ischemia.
Like many other classes of drugs, anti-infective drugs can have a variety of adverse effects. What is the most common, potentially serious, adverse effect of antimicrobial drugs?
Skin rash
Pain
Constipation
Toxic effects on the kidney
A client with acne has been receiving an anti-infective agent for a prolonged period. Initially, the drug was effective, but over time its effectiveness as decreased. What is the nurse’s best action?
Educate the client about the phenomenon of drug tolerance.
Refer the client to the health care provider because the client may be experiencing resistance.
Assess the client for additional signs of superinfection.
Assess the client for a new onset of drug hypersensitivity.
A client is to undergo extensive dental surgery. The dentist prescribes a course of antibiotics before beginning the procedure and continuing for 5 days after the procedure. This is an example of:
chemotherapy.
curative treatment.
prophylaxis.
synergism.
When caring for infants and the elderly who are in need of an antimicrobial agent, the nurse is aware that when compared with doses for young and middle-aged adults, these clients may require:
a higher dose.
the same dose.
the same dose but less frequent.
a lower dose.
A client is to be started on an antibiotic. Which is most important to take into consideration before beginning the antibiotic regimen?
Duration of symptoms
Culture and susceptibility
Client's hydration status
Client's age and weight
Bacitracin (Baciguent) interferes with the cell wall synthesis of which type of bacteria?
Proteus
Streptococcal
Staphylococcal
Pseudomonas
What information about antibiotic therapy should the nurse include in a client’s medication education?
Bacteria can remain in the body for 48 to 72 hours after the completion of antibiotic therapy.
Maintenance of normal bacterial flora is essential to health during the therapy.
The healthy human body hosts dozens of minor infections at any given time.
An aseptic internal environment only exists in young adults.
A nurse is caring for a client who is hospitalized for pneumonia. The nurse reviews the electronic health record and evaluates that the microbiology data does not support the use of the broad spectrum antibiotic. Which statement is the nurse’s best response to the provider about the results?
“I think you need to review the microbiology report for the client.”
“I have reviewed the client’s record and the client does not want the antibiotic.”
“The microbiology data is identifying another antibiotic appropriate for the client.”
“The charge nurse prefers that you call her about the antibiotic coverage for the client.”
A medical nurse on a night shift is reviewing a client's medication administration record for the following day. The nurse notes that a combination antimicrobial drug is prescribed. What is implied by the fact that the client has been prescribed a combination drug?
The client likely has a history of recurrent, multisystemic infections.
The client may have an infection caused by multiple microorganisms.
The client's infection likely has a fungal or protozoal etiology.
The client may be unable to tolerate treatment with a single antimicrobial.
Although the numbers and virulence of microorganisms help determine whether a person acquires an infection, another major factor is:
the number of effective drugs available for serious or antibiotic-resistant infections.
continuous antimicrobial treatment of infections.
the host's ability to defend itself against the would-be invaders.
infections that tend to recur and involve simple organisms.
A client is febrile and is suspected of having a respiratory infection. A sputum culture has been collected and the results of sensitivity testing are expected within 48 hours. The nurse should anticipate that the client may:
need to provide a follow-up sputum culture before medications can be prescribed.
be treated with antiviral medication on a short-term basis.
receive supportive care until an antibiotic can be prescribed in 48 hours.
be immediately prescribed a broad-spectrum antibiotic.
Culture and susceptibility tests are performed prior to the prescription of antimicrobial drugs. What is the specific purpose of the culture test?
predicts the body's response to the infection
identifies the drugs that might be effective in treatment
Identifies the organism causing the infection
determines the severity of the infection
To ensure that the most appropriate drug is being used to treat a pathogen, which would need to be done first?
Evaluating the bactericidal effects
Checking client allergies
Using combination therapy
Obtaining sensitivity testing
What is a major factor that influences whether an individual will acquire an infection?
The person’s ability to defend against invading microorganisms
the number of effective drugs available to an antibiotic-resistant infections
implementation of continuous antimicrobial treatment of the infection
the infection’s tendency to recur and involve simple organisms
A client comes to the clinic reporting mouth sores that appear consistent with an oral yeast infection. The nurse should question the client about recent use of:
antivirals.
oral contraceptive agents.
antibiotics.
antiprotozoals.
The pharmacology instructor is discussing ways to decrease the incidence and severity of adverse effects among children taking anti-infective agents. What would the instructor mention is one way to do this in children?
Decrease dietary potassium.
Keep clients well hydrated.
Assess liver function weekly.
Increase sodium in diet.
A group of nursing students are learning about the factors that underlie recent increases in the incidence and prevalence of antibiotic-resistant microorganisms. What factor is known to contribute to antibiotic resistance?
Increased survival rates from acute infections
Increased population density
Use of antibiotics that are ineffective against the infectious microorganism
Overuse of antibiotics
A client is admitted to the unit. The nurse knows that the client is at high risk for infection. What factors predispose the client to infection? (Mark all that apply.)
Impaired blood supply
Suppression of immune system
Advanced age
Decreased amylase levels
Hypertension
A patient is to begin taking tobramycin (Nebcin) for a nosocomial infection. Which of the following assessments should the nurse prioritize?
The patient's blood pressure
The patient's ideal body weight
The peak and trough blood levels
Other patient medications
The nurse is caring for a 23-year-old female client who uses oral contraceptives and has been prescribed ampicillin for treatment of a respiratory infection. What information is most important for the nurse to share with this client?
Use a type of barrier birth control while you are taking this antibiotic.
Do not take your oral contraceptives while you are taking this medication.
Your menstrual cycle will have a heavier flow while on this medication.
Taking this antibiotic with your oral contraceptives will cause an increased chance of bleeding.
When administering aminoglycosides, the nurse must be aware of which of the following adverse reactions?
Liver necrosis, or hepatic failure
Ototoxicity and nephrotoxicity
Glaucoma and renal failure
Hypoglycemia and hyperglycemia
A public health nurse interacts with many members of the community who are at risk for sexually transmitted infections (STIs). The nurse should anticipate the use of tetracycline in a client who is diagnosed with what STI?
Vaginitis
Chlamydia
Human papillomavirus
Trichomoniasis
A nurse is caring for a patient who has a serious infection. The patient is being treated with combination therapy of a cefazolin and an aminoglycoside. The nurse will be sure to monitor which of the following?
Aspartate aminotransferase levels
Prothrombin time (PT) and partial thromboplastin time (PTT)
Serum BUN and creatinine levels
Serum sodium and potassium levels
What is the rationale for not administering tetracycline to children under the age of 8 years?
It will increase the risk for future infections.
It will interfere with enamel development.
It will increase the risk of heart failure.
It will not treat the infection effectively.
After teaching a group of students about aminoglycosides, the instructor determines that the teaching was successful when the group identifies which drug as the prototype for this class?
Gentamicin
Kanamycin
Tobramycin
Neomycin
The nurse is aware that sulfonamide therapy is used cautiously in older adults because of decreased function of what organ system?
Splenic
Hepatic
Renal
Pancreatic
A 7-year-old child has been taking tetracycline for a bacterial infection. The nurse will be sure to inform the parents that this drug could cause
orange-tinged urine.
staining of permanent teeth.
sleep deprivation.
deep muscle pain.
A female client is diagnosed with hepatitis C as well as a urinary tract infection. The organism is sensitive to tetracycline. Why is the health care provider reluctant to order tetracycline in a client with hepatic impairment?
It slows drug elimination.
It increases drug elimination.
It causes intermittent drug elimination.
It eliminates absorption of the medication.
A 54-year-old woman with a history of osteoporosis has been prescribed ciprofloxacin for recurrent cystitis. Because of the patient's history, the nurse would be sure to discuss with the woman the use of
alcohol.
grapefruit juice.
food containing iron or calcium.
nicotine.
The nurse is preparing to administer amikacin to a client with a complicated Staphylococcus aureus infection. What assessment should the nurse prioritize?
Renal function
Gastrointestinal function
Nutritional status
Muscle strength
A patient has been prescribed a tetracycline drug for Rocky Mountain spotted fever. The patient also takes antacids. Which of the following effects is likely to occur due to an interaction between the two drugs?
Increased risk of bleeding
Increased action of neuromuscular-blocking drugs
Increased profound respiratory depression
Decreased absorption of tetracycline
After teaching a group of nursing students about the different classes of drugs, the instructor determines that the teaching was successful when the students identify drugs that slow or retard the multiplication of bacteria as which types of medication?
bacteriostatic
bactericidal
bacteriostationary
bacteriophage
The health care provider considers prescribing an oral tetracycline for a client suspected of having a urinary tract infection. What action needs to be completed before the medication can be prescribed?
The client should be assessed for penicillin allergy to rule out cross-allergenicity.
The health care provider should order culture and susceptibility studies.
The client should be warned of the risk for fever.
The client should be taught how to store the medication appropriately.
A nurse monitoring a client taking penicillin should be aware of the common GI tract adverse reactions, including which of the following? Select all that apply.
Glossitis
Stomatitis
Esophagitis
Diarrhea
Gastritis
A nurse is preparing a presentation to a local community group about biological weapons. The nurse would identify which disease as lacking an available vaccine?
Anthrax
Plague
Smallpox
Botulism
A client has received a rubella immunization. The client was unaware that she was pregnant. What risk is associated with the administration of the rubella immunization in this client?
Risk of low birth weight infant
Risk of development of the disease in the newborn
Risk of preterm labor
Risk of birth defects
A clinic nurse is administering vaccines at well-baby check-ups. The nurse knows that before administering a DTP vaccine, the nurse should check what vital sign?
Respirations
Temperature
Pulse
Blood pressure
A client develops fever and arthralgia 4 days after the administration of tetanus toxoid. What reaction to the vaccine is this?
Serum sickness
Infectious process
Anaphylaxis
Distress syndrome
A nurse should screen clients of child-bearing age for pregnancy as the administration of which vaccines is contraindicated during pregnancy? (Select all that apply.)
Influenza
Varicella
Mumps
Rubella
Measles
A client who was bitten by a pit viper is to receive antivenin. What is the nurse’s best action?
Establish IV access
Obtain a 1 mL syringe
Obtain a 3 mL syringe
Assess the client’s oral mucosa
A nurse is administering a mumps vaccine to an adolescent. Which medication should be available when administering an immunization?
Diphenhydramine
Hydroxyzine
Physostigmine
Epinephrine
The school nurse is participating in a program to immunize students against human papillomavirus (HPV). What benefit should the nurse describe to students and their families?
Reduced risk for cervical cancer
Protection against several viral sexually transmitted infections
Reduced risk for polycystic ovary syndrome
Reduced risk for pelvic inflammatory disease (PID)
The nurse is assessing a 6-month-old infant prior to scheduled immunizations. What finding would the nurse immediately recognize as a reason to reschedule administration?
low-grade fever
current history of feeding poorly
current history of loose stools
demonstrating fussiness and crying
A group of students are role-playing scenarios involving biological weapon exposure. Which medication would the students identify as using for a client with cutaneous anthrax?
Ribavirin
Ciprofloxacin
Streptomycin
Gentamicin
When providing client teaching to parents regarding measles, mumps, and rubella vaccine administration, which is most important regarding the schedule for administration?
It is administered at 12 to 15 months.
It is administered at 5 to 6 months.
It is administered at 1 to 2 months.
It is administered at 3 to 4 months.
The nurse is providing wellness information to a 50-year-old client who is employed as a paramedic. The client asks what, if any, vaccines the client should get. What is the nurse’s best response?
Tetanus and pertussis
Shingles
Hepatitis B once and influenza vaccine annually
Tetanus-diphtheria-pertussis; hepatitis B vaccine once; influenza vaccine annually
Which is an example of artificially acquired active immunity? (Select all that apply.)
An individual who is exposed to chickenpox for the first time and has no immunity to the disease.
Administration of the varicella vaccine to an individual who has no immunity to the disease.
An individual who is exposed to pertussis for the first time and has no immunity to the disease.
Administration of the influenza vaccine to an individual who has no immunity to the disease.
Administration of the rubella vaccine to an individual who has no immunity to the disease.
The administration of immunizations to a client is a form of what type of immunity?
Attenuated active immunity
Naturally active immunity
Artificial active immunity
A client tells the nurse that she has taken several doses of over-the-counter fluconazole to treat a "yeast infection." When assessing the client's risk for drug toxicity, what aspect of the client's health status should the nurse prioritize?
The client has decreased renal function following recent pyelonephritis
The client has type 2 diabetes and takes oral hypoglycemics
The client has lost over 30 lbs. in the past four months through diet and exercise
The client experienced a transfusion reaction to packed red blood cells several years ago
Amphotericin B is given by which route?
IV
IM
PO
SQ
Caspofungin has been prescribed for a client diagnosed with invasive aspergillosis. The nurse should teach the client to promptly report what symptom associated with an adverse reaction?
Dry mouth
Diaphoresis
Cardiac distress
Muscle pain
An adult client, recently diagnosed with a tinea infection, has begun treatment with griseofulvin. During a scheduled clinic visit, the client states to the nurse, “I'm pretty good at reading my body's signals, so I make sure to take a bit extra when I think my infection is getting worse.” This client's statement is suggestive of what nursing diagnosis?
deficient knowledge related to correct use of griseofulvin
effective therapeutic regimen management related to symptom identification
ineffective coping related to self-medication
The client is receiving ketoconazole. The nurse should be concerned about a drug–drug interaction on the basis of what other comorbidity?
Type 2 diabetes
Chronic pain
Venous ulcers
Penicillin allergy
The azole antifungals are contraindicated in clients with what condition?
Increased liver enzymes
Pancreatitis
Hypovolemia
HIV
A nurse is instructing a 19-year-old female patient on the use of fluconazole for candida vaginitis. A teaching priority will be to:
take an antiemetic or antidiarrheal for adverse GI effects.
use an alternative form of birth control, if taking an oral contraceptive.
use an aspirin for relief of minor discomforts.
take the drug with food.
A client is being treated with amphotericin B. Which statement indicates that the client has understood the client teaching?
“The medication may cause diabetes.”
“The medication will cause liver necrosis.”
“The medication may cause kidney damage.”
“The medication will cause pancreatitis.”
A nurse is caring for a client who asks why she has been prescribed posaconazole following kidney transplantation. The nurse responds that posaconazole is used as prophylaxis to prevent:
Aspergillus infection.
mucormycosis.
blastomycosis.
coccidioidomycosis.
The primary health care provider prescribes flucytosine to treat a systemic fungal infection. The nurse would administer this drug by which route?
oral
IV
IM
topical
A client is receiving amphotericin B. The nurse would assess the client closely for which adverse reaction?
renal impairment
intensive weight loss
skin discoloration
CNS disorders
The critical care nurse is administering intravenous anidulafungin to a client for the treatment of candidemia. The client’s blood urea nitrogen and creatinine levels have been rising in recent days due to adverse effects of other medications. What is the nurse’s best action?
Hold the medication pending the provider’s reassessment of the client
Confirm the drug with the provider
Administer the medication as prescribed because it is not excreted renally
Confirm the route with the provider
Which statement would be correct for a client regarding the administration of an antifungal medication?
Instruct the client to take a forgotten dose as soon as it is remembered, even if it is time for the next dose.
Advise that for persistent headache, unrelieved by acetaminophen, the client should increase the dosage of acetaminophen.
Instruct the client to complete the entire drug therapy even if a dose is missed.
Instruct the client to take frequent meals of fat and protein when GI distress occurs.
Amphotericin B is ordered for a client with thrush. How does the drug combat the infection?
It acts on the fungal cell membrane.
It increases reproduction of fungal cells.
It improves fungal protein synthesis.
A client has been prescribed sulconazole for the treatment of tinea pedis. When nursing diagnosis should the nurse identify when planning this client's care?
Risk for injury related to central nervous system depression
Impaired urinary elimination related to nephrotoxicity
Risk for impaired skin integrity related to local irritation
Imbalanced nutrition: Less than body requirements related to liver damage
The nurse is educating an 82-year-old client regarding amphotericin B (Fungizone). The nurse knows the client understand when the client states that he could develop which adverse effect?
Diabetes
Liver necrosis
Damage to his kidneys
Pancreatitis
An older adult resident of a long-term care facility has been diagnosed with a fungal infection and has been prescribed fluconazole. What change in the client’s laboratory values may necessitate a change in medication therapy?
decreased hematocrit and hemoglobin
increased white blood cells
decreased creatinine clearance
decreased erythrocyte sedimentation rate (ESR)
The nurse at a long-term care facility is admitting a new resident who is an older adult. The resident's current medication regimen includes nystatin 1,000,000 units PO t.i.d. The nurse should recognize the need to prioritize what aspect of this resident's care?
Mouth care
Encouraging fluid intake
Protective isolation
Daily use of an antibacterial shampoo
An older adult client has been diagnosed with candidiasis and prescribed fluconazole. What aspect of the client's health status should warrant close monitoring by the nurse?
The client has atrial fibrillation and takes warfarin daily
The client adheres strictly to a vegetarian diet
The client has hypothyroidism and takes levothyroxine daily
The client has a low body mass index
An adult client is brought to the emergency department after deliberately overdosing on acetaminophen. The care team should prioritize interventions based on the client’s risk for which adverse reaction?
seizures
liver failure
acute GI bleed
gastric perforation
A client with acute joint inflammation tells the nurse , “I’ve been taking acetaminophen as it’s ordered on the bottle, but my swelling and inflammation doesn’t seem to be getting better.” What should the nurse teach the client?
"Acetaminophen has no effect on inflammation.”
"It takes some people a few weeks to feel a difference.”
“Acetaminophen’s only clinical use is for pain treatment.”
“Keep taking it as ordered, and watch for any signs of bleeding.”
A client is receiving auranofin as treatment for rheumatoid arthritis. The nurse should expect this drug to be given by which route?
Oral
Subcutaneous
IM
IV
A nurse is caring for a client who has just been diagnosed with rheumatoid arthritis. What first-line treatment should the nurse anticipate?
auranofin
balsalazide
ibuprofen
The client has been prescribed one aspirin a day. The nurse understands that is prescribed for which of the following?
To treat osteoarthritis
To inhibit platelet aggregation
To decrease pain
To decrease temperature
A salicylate is contraindicated in clients who have had surgery within the past week for which reason?
Increased risk for allergic reaction
Increased risk for bleeding
Increased risk for fluid imbalance
Increased risk for toxicity
A group of nursing students are reviewing the pain-relieving action of NSAIDs. The students demonstrate understanding of the information when they identify which actions as being blocked to achieve pain relief?
cyclooxygenase-2
cyclooxygenase-1
cyclooxygenase-3
cyclooxygenase-4
The client has been prescribed the nonsteroidal anti-inflammatory drug (NSAID) naproxen/esomeprazole. The nurse teaches the client the potential adverse reactions include heartburn, nausea and what other reaction?
Diarrhea
Vomiting
Dizziness
Rash
An 11-year-old client is having a cavity filled in the left mandibular first molar. The health care provider has prescribed aspirin for pain relief after the procedure. The nurse discovers upon assessment that the child is suffering from a flulike illness. The nurse contacts the health care provider about the prescribed medication for pain. What is the risk if aspirin is administered to this client?
Reye syndrome
Excess antiplatelet action
Asthma
Salicylate poisoning
A woman who is in the second trimester of her first pregnancy has been experiencing frequent headaches and has sought advice from her nurse practitioner about safe treatment options. What analgesic can the nurse most safely recommend?
Aspirin
Diflunisal (Dolobid)
Acetaminophen
Ibuprofen
A child has symptoms of influenza, including a fever. Which medication should not be administered to the child because of the risk of Reye's syndrome?
Acetaminophen
Acetylsalicylic acid
Ibuprofen
Ascorbic acid
A nurse is aware that a client prescribed meloxicam is most likely being treated for what health problem?
fever
arthritis
migraine
a chronic wound
