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Cell Communication

Total questions: 54

Worksheet time: 58mins

Name
Class
Date
1.

cAMP is best described as a (an)

a)

Energy carrying molecule

b)

Secondary Messenger molecule

c)

Membrane Ligand

d)

Receptor molecule

2.
A signal molecule that binds to a plasma-membrane protein is a
a)
ligand
b)
second messenger
c)
protein kinase
d)
receptor protein
3.
What is a G protein?
a)
specific type of membrane-receptor protein
b)

molecular switch on the cytoplasmic side of a membrane

c)

cytochrome complex within the plasma membrane

d)

transmembrane protein

4.
Which of the following can activate a protein by transferring a phosphate group to it?
a)
cAMP
b)
G Protein
c)
protein kinase
d)
protein phosphatase
5.
What do second messengers do?
a)
transport a signal through the lipid bilayer
b)
relay a signal from the outside to the inside of the cell
c)

relay message from the inside of the membrane throughout the cytoplasm

d)
dampen the message
6.
What is a function of the second messenger IP3?
a)
bind to and activate protein kinase A
b)
activate transcription factors
c)
convert ATP to cAMP
d)
bind to and open ligand-gated channels
7.
Which of the following is involved in many human medicines for disease?
a)
cAMP
b)
Calcium concentration
c)
G-protein pathways
d)
receptor tyrosine kinases
8.
Signal amplification is most often achieved by
a)
an enzyme cascade
b)
binding of multiple signals
c)
branching pathways
d)
action of adenylyl cyclase
9.
What does a protein kinase do?
a)

removes phosphates from proteins

b)
transfers phosphates from ATP to proteins
c)
activates an enzyme
d)

Transfer phosphates to nucleotides

10.
What does a protein phosphatase do?
a)
removes phosphates
b)
transfers phosphates from ATP to proteins
c)
activates an enzyme with a signal molecule
11.
What is a phosphorylation cascade?
a)
travelling of hormones through the air
b)
travelling of hormones through the blood
c)
the removal of a phosphate
d)
a series of molecules that get phosphorylated
12.
What determines whether a cell is a target cell for a particular signal molecule?
a)
phosphorylation cascade
b)
cAMP
c)
signal receptors
d)
phosphatase
13.
Do plant cells communicate using hormones?
a)
yes
b)
no
14.
What determines whether a signal molecule binds on the surface or enters the cell?
a)
size
b)
polarity
c)
ability to cross the membrane
d)
all of these are correct
15.
Which of the following converts cAMP to AMP?
a)
phosphodiesterase
b)
protein phosphatase
c)
GTPase
d)

ATP synthase

16.
Which of the following is a chemical message that usually travels through the bloodstream to target cells?
a)
hormone
b)
local regulator
c)
endocrine cell
d)

G-Protein

17.
A signal molecule that binds to a plasma-membrane protein is a
a)
ligand
b)
second messenger
c)
protein kinase
d)
receptor protein
18.
What is a G protein?
a)
specific type of membrane-receptor protein
b)
protein on the cytoplasmic side of a membrane
c)
membrane-bound enzyme
d)
relay protein
19.
Which of the following can activate a protein by transferring a phosphate group to it?
a)
cAMP
b)
G Protein
c)
protein kinase
d)
protein phosphatase
20.
What do second messengers do?
a)
transport a signal through the lipid bilayer
b)
relay a signal from the outside to the inside of the cell
c)
relay message from the inside of the mebrane throughout the cytoplasm
d)
dampen the message
21.
Signal amplification is most often achieved by
a)
an enzyme cascade
b)
binding of multiple signals
c)
branching pathways
d)
action of adenylyl cyclase
22.
What does a protein kinase do?
a)
removes phosphates
b)
transfers phosphates from ATP to proteins
c)
activates an enzyme
23.
What does a protein phosphatase do?
a)
removes phosphates
b)
transfers phosphates from ATP to proteins
c)
activates an enzyme with a signal molecule
24.
What is a phosphorylation cascade?
a)
travelling of hormones through the air
b)
travelling of hormones through the blood
c)
the removal of a phosphate
d)
a series of molecules that get phosphorylated
25.
What determines whether a cell is a target cell for a particular signal molecule?
a)
phosphorylation cascade
b)
cAMP
c)
signal receptors
d)
phosphatase
26.
Do plant cells communicate using hormones?
a)
yes
b)
no
27.
Which of the following converts cAMP to AMP?
a)
phosphodiesterase
b)
protein phosphatase
c)
GTPase
28.
Which of the following is a chemical message that usually travels through the bloodstream to target cells?
a)
hormone
b)
local regulator
c)
endocrine cell
29.
The 3 steps of signal transduction in order are
a)
reception, transduction, response
b)
response, transduction, reception
c)
reception, response, transduction
d)
transduction, reception, response
30.

In cell signaling, how is the flow of specific ions

regulated?

a)

Opening and closing of ligand-gated channels

b)

Transduction

c)

Cytoskeleton rearrangement

d)

Endocytosis

31.

Many signal transduction pathways use second messengers to:

a)

transport a signal through the lipid bilayer portion of the plasma membrane.

b)

relay a signal from the outside to the inside of the cell.

c)

relay the message from the inside of the membrane throughout the cytoplasm.

d)

amplify the message by phosphorylating proteins.

32.

In cell signaling, how is the flow of specific ions

regulated?

a)

Opening and closing of ligand-gated channels

b)

Transduction

c)

Cytoskeleton rearrangement

d)

Endocytosis

33.

Which of the following can activate a protein by transferring a phosphate group to it?

a)

cAMP

b)

G proteins

c)

phosphodiesterase

d)

protein kinase

34.

What could happen to the target cells in an animal that lack receptors for local regulators?

a)

They could compensate by receiving nutrients via an α factor.

b)

They could develop normally in response to neurotransmitters instead.

c)

They could divide but never reach full size.

d)

They would not be able to multiply in response to growth factors from nearby cells.

35.
Which of the following would be an example of paracrine signaling in animals?
a)
neurotransmitter acetylcholine
b)
hormone epinephrine
c)
neurotransmitter norepinephrine
d)
growth factor
36.
A signal molecule that binds to a plasma-membrane protein is a
a)
ligand
b)
second messenger
c)
protein kinase
d)
receptor protein
37.
What is a G protein?
a)
specific type of membrane-receptor protein
b)
protein on the cytoplasmic side of a membrane
c)
membrane-bound enzyme
d)
relay protein
38.
Which of the following can activate a protein by transferring a phosphate group to it?
a)
cAMP
b)
G Protein
c)
protein kinase
d)
protein phosphatase
39.
What do second messengers do?
a)
transport a signal through the lipid bilayer
b)
relay a signal from the outside to the inside of the cell
c)
relay message from the inside of the mebrane throughout the cytoplasm
d)
dampen the message
40.
Signal amplification is most often achieved by
a)
an enzyme cascade
b)
binding of multiple signals
c)
branching pathways
d)
action of adenylyl cyclase
41.
What does a protein phosphatase do?
a)
removes phosphates
b)
transfers phosphates from ATP to proteins
c)
activates an enzyme with a signal molecule
42.
What is a phosphorylation cascade?
a)
travelling of hormones through the air
b)
travelling of hormones through the blood
c)
the removal of a phosphate
d)
a series of molecules that get phosphorylated
43.
What determines whether a signal molecule binds on the surface or enters the cell?
a)
size
b)
polarity
c)
ability to cross the membrane
d)
all of these are correct
44.
Which of the following is a chemical message that usually travels through the bloodstream to target cells?
a)
hormone
b)
local regulator
c)
endocrine cell
45.
Which of the following shows the correct sequence of the cell cycle?
a)
Mitosis-> G1->S->G2->cytokinesis
b)
S->G1-> G2-> mitosis-> cytokinesis
c)
cytokinesis->mitosis->G1->S->G2
d)
 G1->S->G2->mitosis->cytokinesis
46.
As you get dehydrated, your blood becomes thicker and harder to pump. Your kidneys will respond by stopping urine production, sending the water from urine into your bloodstream to thin your blood back to normal level.
a)
Positive Feedback Response
b)
Negative Feedback Loop 
47.
When you get cut, your skin cells release hormones that signal platelets to come and stop the bleeding. Platelets then release more hormones that signal even more platelets to help stop bleeding. The hormone signals continue until the cut is closed.
a)
Positive Feedback Response
b)
Negative Feedback Loop 
48.
Structure (b) is a ____.
a)
chromosome
b)
chromatid
c)
centromere
49.

A feedback loop best fits which characteristic of life?

a)

Cells

b)

Organization

c)

Homeostasis

d)

Adaptation

50.

According to the feedback loop, what does high blood sugar promote?

a)

Insulin Release

b)

Glucagon Release

c)

Insulin Uptake

d)

Glycogen Uptake

51.

Cyclins are small proteins that bind to and activate CDK enzymes during the process of:

a)

endocytosis

b)

cell respiration

c)

osmosis

d)

mitosis

52.

Cells can communicate with one another via:

a)

chemical messengers

b)

hormones

c)

gap junctions

d)

all of these

53.

When does DNA replication occur?

a)

before M Phase

b)

During M Phase

c)

Directly following telophase

d)

During G0

54.

G1 is associated with what event?

a)

doubling of cell content

b)

DNA replication

c)

The beginning of mitosis

d)

breakdown of the nuclear membrane