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WorksheetsBrivace (Brivaracetam)
Total questions: 30
Worksheet time: 15mins
Brivaracetam belongs to which class of anti-epileptics
1st generation
2nd generation
3rd generation
4th generation
Brivaracetam binds to which of the following receptor
AMPA
SV2A
Na+ channels
Ca++ channels
Brivaracetam differs from 2nd generation anti-epileptic in its
Non-selectivity
Selectivity
Bioavailability
None of the option
Brivaracetam is __________ times more potent than 2nd generation anti-epileptic
10-15 times
15-20 times
15-30 times
20-30 times
Which of the following is the first selective SV2A modulator
Sodium valproate
Eslicarbamezapine
Levetiracetam
Brivaracetam
Which of the following is not a feature of Brivaracetam?
Non-selectivity
Better tolerability
Higher potency
Higher lipophilicity
Higher lipophilicity relates to ____________
Faster brain penetration & slow onset of action
Slow brain penetration & slow onset of action
Faster brain penetration & faster onset of action
Slow brain penetration & faster onset of action
Percentage of Drug available in blood to perform action is called?
Absorption
Diffusion
Metabolism
Bioavailability
Bioavailability of Brivaracetam is
Near to 50%
Near to 70%
Near to 90%
Near to 100%
Which of the following is not a characteristic of Brivaracetam?
Minimal psychiatric adverse effects
No weight gain
High drug-drug interaction
Pregnancy category C
Major side effect of sodium valproate is:
depression
hepato-toxic
anxiety
kidney stones
Major side effect of carbamezapinei is
osteoporosis
kidney stones
baldness
swelling
Brivaracetam is better than Levetiracetam because:
Has less binding affinity at SV2A
Has less tolerability
Has higher potency
Has slow onset of action
Brivaracetam is indicated in patients of age:
1 year & above
1 month & above
1 week & above
1 day & above
Recommended dose of patients aged 16 & above is:
20mg BD
30mg BD
40mg BD
50mg BD
Dose of Brivaracetam for a patient aged 3 years & weight 20kg:
10mg morning & 10mg evening
20mg morning & 20mg evening
30mg morning & 30mg evening
40mg morning & 40mg evening
Price of Brivace 25mg is:
34 Rs. Per tab
36 Rs. Per tab
38 Rs. Per tab
40 Rs. Per Tab
Brivace (Brivaracetam) is indicated for the management of:
Epilepsy
Generalized epilepsy
Partial Epilepsy
Status Epilepticus
Which of the following is not a potential prescriber of Brivace (Brivaracetam)?
Neurophysician
Neurosurgeon
Pediatrician
Pulmonologist
Per Tab price for 50mg Brevera is:
69 Rs. Per Tab
79 Rs. Per Tab
89 Rs. Per Tab
99 Rs. per Tab
Per Tab Price for 25mg Brivatam is:
40 Rs. Per Tab
50 Rs. Per Tab
60 Rs. Per Tab
70 Rs. per Tab
Which of the following is not a side effect of Brivaracetam?
Dizziness
Somnolence
Irritability
Weight gain
Half-life of Brivaracetam is:
6 hours
7 hours
8 hours
9 hours
During depolarization process:
3 Na+ moves inside & 2K+ moves outside
2 Na+ moves inside & 3K+ moves outside
3 Na+ moves outside & 2K+ moves inside
2 Na+ moves outside & 3K+ moves inside
Which of the following is an excitatory neurotransmitter?
Glutamate
GABA
Serotonin
Dopamine
Which of the following is an inhibitory neurotransmitter?
Glutamate
GABA
Serotonin
Dopamine
Site where a Drug or neurotransmitter binds on a cell is called?
Receptor
Synapse
Dendrite
Nucleus
Cognitive impairment Is associated with
Sodium valproate
Carbamazepine
Brivaracetam
Levetiracetam
Which of the following is better suited for school going epileptic patients?
Sodium valproate
Brivaracetam
Carbamazepine
Phenytoin
Which of the following is better suited for epileptic patients with psychiatric symptoms?
Levetiracetam
Gabapentin
Brivaracetam
Carbamazepine
