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WorksheetsGenetic Disease Quiz
Total questions: 36
Worksheet time: 22mins
Cystic Fibrosis
Autosomal recessive, mucus build up in the respiratory (lungs) system
Autosomal dominant, benign tumors under the skin
Females – XXX
Sex-linked, wasting away of muscles
Down Syndrome
Females – XO
Sex-linked, blood does not clot
Trisomy 21
Autosomal recessive, impairs nervous system, infants screened at birth
Hemophilia
Autosomal recessive, mucus build up in the respiratory (lungs) system
Deformed shape of red blood cells
Sex-linked, myelin stripped from neurons
Sex-linked, blood does not clot
Sickle-cell Disease
Deformed shape of red blood cells
Huntington's Disease
Autosomal dominant, benign tumors under the skin
Autosomal recessive, brain deterioration, affects Jews, death by age 5
Huntington's Disease
Trisomy 21
Sex-linked, X chromosome is nearly broken off
Males – XXY
Autosomal dominant, degeneration of the brain, onset during middle age
Fragile X Syndrome
Autosomal dominant, benign tumors under the skin
Sex-linked, X chromosome is nearly broken off
Females – XO
Autosomal recessive, brain deterioration, affects Jewish People in a large proportion, death by age 5
Autosomal recessive, brain deterioration, affects Jewish People in a large proportion, death by age 5
Phenylketonuria (PKU)
Duchenne Muscular Dystrophy
Klinefelter's Syndrome
Tay-Sachs Disease
Males – XYY
Jacobs Syndrome
Turner Syndrome
Adrenoleukodystrophy (ALD)
Tay-Sachs Disease
Neurofibromatosis
Sex-linked, wasting away of muscles
Autosomal recessive, mucus build up in the respiratory (lungs) system
Autosomal dominant, benign tumors under the skin
Autosomal dominant, degeneration of the brain, onset during middle age
Turner Syndrome
Males – XXY
Females – XO
Trisomy 21
Males – XYY
Sex-linked, wasting away of muscles
Duchenne Muscular Dystrophy
Hemophilia
Neurofibromatosis
Autosomal dominant, degeneration of the brain, onset during middle age
Klinefelter's Syndrome
emales – XO
Deformed shape of red blood cells
Males – XYY
Males – XXY
Autosomal recessive, impairs nervous system, infants screened at birth
Poly-X
Phenylketonuria (PKU)
Adrenoleukodystrophy (ALD)
Klinefelter's Syndrome
Poly-X
Sex-linked, X chromosome is nearly broken off
Males – XYY
Females – XXX
Males – XXY
Adrenoleukodystrophy (ALD)
Autosomal recessive, mucus build up in the respiratory (lungs) system
Autosomal dominant, benign tumors under the skin
Sex-linked, myelin stripped from neurons
Sex-linked, blood does not clot
Male Sex Chromosomes are (a)
Female Sex Chromosomes are (a)
How many PAIRS of chromosomes can we see on a Karyotype of a human?
18
23
36
46
What gametes can a female pass on
ONLY X
X or Y
ONLY Y
What is the natural probability of someone having a boy as a child?
25%
75%
50%
0%
In Pedigree's a circle represents a
Female
Male
Grandfather
Grandmother
How can you tell if a pedigree is autosomal dominant?
See if you can make a punett square
See if there are males only
See if there are any carriers
See if there are females only
If a trait or disease is sex linked what chromosome will it appear on?
Chromosome 21
Chromosome 18
Sex Chromosomes
Chromosome 20
What does nondisjunction mean?
When the X and Y are flipped
When chromosomes don't separate correctly in Meiosis
When cells accidentally divide
When the cell splits too many times
What sex chromosomes can a male pass on to his offspring?
ONLY X
X and Y at the same time
ONLY Y
one X OR one Y
How do mutations occur?
Our bodies either make them by mistake, or we get them from chemicals from our surroundings
If humans are bit by an animal when they are young
How many total autosomes do human have?
46
43
45
44
What does trisomy mean?
3 copies of a chromosome instead of 2
One copy of a chromosome instead of 2
Has an enlarged chromosome number 3
Has a smaller than normal chromosome number 3
What advantage does someone who has sickle cell anemia have?
No advantage
More rigid blood cells
Immunity to typhoid fever
Immune to malaria
Why would a genetic disease remain in a population if it is fatal?
It is only present in heterozygotes
It makes heterozygotes resistant to the fatal disease
It disappears but continuously but is replaced due to mutations
It occurs only in certain geographic range
How many human genetic disorders are there?
8
23
46
1000+
When does nondisjunction occur?
Mitosis
Anaphase
Meiosis
When gametes are forming
What is a Barr body?
The inactive X chromosome in Females
The inactive X chromosome in Males
The active X chromosome
Linebacker for the Minnesota Vikings
What human trait is inherited through both Codominance and Multiple Alleles?
Hair Color
Hand Size
Blood Type
Height
If two golden retrievers have 12 puppies how many are likely to be females?
8
4
7
6
This Pedigree is of a...
Gene
Autosomal Recessive Trait
Sex-Linked
Autosomal Dominant Trait
