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Year 12 Biology - DNA, RNA and replication

Total questions: 40

Worksheet time: 54mins

Name
Class
Date
1.
What does DNA stand for?
a)
Deoxyribonucleic acid
b)
Denitrogenous acid
c)
Deribonucleic acid
d)
Diribonucleic acid
2.
Which of the following best describes a DNA molecule?
a)
double helix
b)
contains ribose
c)
made of amino acids
d)
contains Uracil
3.
DNA is a polymer made of:
a)
Nucleotides
b)
Ribosomes
c)
Purines
d)
Pyrimidines
4.
Why is DNA important?
a)
it is very small and very complicated
b)
it's in everything
c)
it serves as the blueprint for traits of all living things
d)
because we eat it every day for energy
5.
In a molecule of double-stranded DNA, the amount of Adenine present is always equal to the amount of
a)
cytosine
b)
guanine
c)
thymine
d)
uracil
6.
What determines the code, or information, of a DNA molecule?
a)
the shape (structure) of the nitrogen bases
b)
the order (sequence) of the nitrogen bases
c)
the color of the nitrogen bases
d)
the frequency (number) of nitrogen bases
7.
Which 2 molecules form the sides (backbone) of the DNA ladder?
a)
deoxyribose sugar and adenine
b)
deoxyribose sugar and a hydrogen bond
c)
deoxyribose sugar and the nucleus
d)
deoxyribose sugar and phosphate
8.
What will the matching sequence be on a strand that reads AAGCTAT?
a)
AACGATA
b)
TTCGTTA
c)
CCTGATA
d)
TTCGATA
9.
What are the three components of a nucleotide?
a)
sugar, hydrogen, nitrogen base
b)
sugar, oxygen, nitrogen base
c)
sugar, phosphate, nitrogen base
d)
sugar, phosphate, protein
10.
Name this structure
a)
double helix
b)
nucelotide
c)
twisted ladder
d)
hydrogen bond
11.
Which series is arranged in order from largest to smallest in size?
a)
gene, chromosome, nucleus, cell, DNA, nucleotide
b)
cell, nucleus, chromosome, DNA, gene, nucleotide
c)
nucleotide, chromosome, cell, DNA, nucleus
d)
cell, DNA, gene, nucleotide, nucleus, chromosome
12.
Which enzyme is responsible for adding nucleotides?
a)
Topoisomerase
b)
DNA Polymerase
c)
Ligase
d)
Primase
13.
Which sequence of DNA bases would pair with this partial strand
ATG TGA CAG
a)
ATG TGA CAG
b)
TAC ACT GTC
c)
GTA AGT GAC
d)
CAT TCA CTG
14.
A process in which DNA has the unique ability to make an exact copy of itself.
a)
Replication
b)
Translation
c)
Transcription
15.
Nitrogenous bases are joined by which type of bond?
a)
polar bonds
b)
ionic bonds
c)
covalent bonds
d)
hydrogen bonds
16.
In what phase of the cell cycle does DNA replication take place?
a)
G1
b)
S
c)
G2
d)
M
17.

Which enzyme is responsible for unzipping or the DNA molecule when replication begins?

a)

Helicase

b)

DNA breakase

c)

Primase

d)

DNA polymerase

18.

Which enzyme is responsible for gluing together the Okasaki fragment on the lagging strand during DNA replication?

a)

Ligase

b)

Helicase

c)

Amaylase

d)

DNA polymerase

19.

Where does the DNA molecule unzip at during DNA replication?

a)

Between the sugar and phosphate

b)

Between the sugar and nitrogen bases

c)

Between the nitrogen bases

20.
DNA replication results in two DNA molecules,
a)
each one with two original strands
b)
each one with two new strands
c)
each one with one new strand and one original strand
d)
one with two new strands and the other with two original strands
21.
order of replication
a)
3, 2, 1, 4
b)
2, 1, 4, 3
c)
2, 3, 1, 4
d)
3, 4, 1, 2
22.

Proteins are formed from the monomers called

a)

nucleotides

b)

nitrogen bases

c)

nucleic acids

d)

amino acids

23.

What sugar is in RNA?

a)

ribose

b)

deoxyribose

c)

glucose

d)

fructose

24.
In a strand of DNA, if it contains 20% of Thymine, then how much Guanine would be present?
a)
30%
b)
20%
c)
80%
d)
10%
25.
Which of the following units are repeatedly joined together to form a strand of DNA?
a)
amino acids
b)
nucleotides
c)
fatty acids
d)
polysaccharides
26.
Which of the following statements is true?
a)
DNA is single-stranded
b)
RNA is single-stranded
c)
DNA contains uracil
d)
RNA contains deoxyribose
27.
What is the difference between DNA and RNA in terms of bases?
a)
RNA contains uracil in place of thymine
b)
RNA contains uracil in place of adenine
c)
RNA contains uracil in place of guanine
d)
RNA contains uracil in place of  cytosine
28.
What did Erwin Chargaff conclude from his experiments?
a)
Nitrogen bases are held together by peptide bonds
b)
A and T, C and G always occur in equal amounts
c)
Proteins are the carriers of genetic information
d)
C and G rarely occur in eukaryotic organisms
29.

A gene is (mark all that apply)

a)

A distinct portion of the somatic cells responsible for increasing hormone concentrations during interphase

b)

A distinct sequence of nucleotides forming part of the chromosome

c)

A unit of heredity transferred from the parents to their offspring

d)

A type of protein

30.

The picture below shows the steps of DNA replication beginning with step one and ending with step three.


​Because you are reusing the old, or parent, DNA strand DNA replication is said to be

a)

Semi- Conservative

b)

Semi-discontinuous

c)

Continuous

d)

Fully-Conserveative

31.

Which is the first step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

32.

Which is the second step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

33.

Which is the third step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

34.

Which is the fourth step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

35.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

36.

Which letter in the picture below depicts the lagging strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

37.

Which letter in the picture below depicts the replication fork in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

38.

DNA replication runs from ______' to _____' and is said to be ______________________

a)

5, 3, antiparallel

b)

3, 5, antiparallel

c)

5, 3, parallel

d)

3, 5, parallel

39.

Okazaki fragments appear on which strand of DNA during DNA replication?

a)

lagging

b)

leading

40.

Enzyme that connects the DNA to the backbone (glues)

a)

Ligase

b)

Polymerase

c)

Helicase

d)

Primase