WorksheetsPharm II: Part 2 Antihypertensive
Total questions: 26
Worksheet time: 17mins
The suffix for calcium-channel-blocking agents (CCB's) is:
-statin
-olol
-dipine
-ine
Angiotensin-Converting Enzyme Inhibitors (ACEI's) are now recommended for all patients with ________ heart failure...
Stage A
Stage B
Stage C
Stage D
ACEI's improve symptoms of HF within a period of __ to___ weeks.
3-4 weeks
8-10 weeks
10-12 weeks
4-12 weeks
ACEI's are now considered first-line therapy and are the cornerstone of HF therapy.
True
False
The suffix for ACEI's is:
-pril
-olol
-statin
-dipine
ACEI's are commonly used as anti-hypertensives and are well tolerated.
True
False
Examples of some ACEI's are:
captopril (Capoten)
enalapril (Vasotec)
irbesartan (Avapro)
lisinopril (Prinivil, Zestril)
ACEI's slow the progression of diabetic nephropathy (long-term kidney disease) whether hypertension is present or not.
True
False
ACEI's:
Blocks the amount of sodium and water that leave the body
Blocks the conversion of angiotensinogen to angiotensin I
Blocks the kidneys from releasing renin
Blocks ACE's from converting angiotensin I to angiotensin II
Angiotensin I causes vasoconstriction (increasing peripheral vascular resistance) and stimulates the adrenal cortex to release aldosterone, facilitating water retention.
When these events are blocked, the blood pressure is lowered.
The first statement is true and the second statement is false.
Both statements are false.
The first statement is false and the second statement is true.
Both statements are true.
The anti-hypertensive effects of ACEI's are not reduced by administration of NSAID's.
True
False
Angiotensin Receptor Blockers (ARB's) act by attaching to the angiotensin II receptor and blocking the effect of angiotensin II.
ARB's end with the suffix -artan.
Both statements are false.
The first statement is false and the second statement is true.
The first statement is true and the second statement is false.
Both statements are true.
ACEI's may be used alone or in combo with:
a β-blocker
thiazide diuretic
CCB
NSAID's
None of these
________ is the prototype ARB.
valsartan (diovan)
losartan (Cozaar)
azilsartan (Edarbi)
irbesartan (Avapro)
ARB's block the vasoconstricting action of angiotensin II and also blocks the aldosterone-secreting effects of angiotensin II.
True
False
Just like ACEI's, ARB's may cause CNS effects such as:
dizziness
fatigue
insomnia
headache
Adverse reactions of ACEI's:
hypotension
allergic reactions
dry cough
neutropenia
diabetic neuropathy
Diuretics, ACEI's, ARB's, and CCB's are The Big Four Anti-hypertensive groups.
True
False
Throwback:
(Autonomic Nervous System--> Sympathetic Nervous System & Parasympathetic Nervous System )
statement: The parasympathetic nervous system is the "fight or flight" and cholinergic receptors work for this system.
The first part of the statement is true but the second part of the statement is false.
Both parts of the statement are true.
Both parts of the statement are false.
The first part of the statement is false but the second part of the statement is true.
Direct renin inhibitors (newer type of anti-hypertensive) work by:
binding to renin, thereby reducing the levels of angiotensin I, thus angiotensin II, & ultimately aldosterone.
breaking down renin completely
acting on the kidney by inhibiting its ability to release renin
none of these
The suffix for Calcium Channel Blocking Agents is -dipine.
True
False
CCB's work by:
breaking down extra calcium that is in the blood
causing vasoconstriction
inhibiting the movement of intracellular calcium ions out of cells, including vascular smooth muscle and cardiac cells.
inhibiting the movement of extracellular calcium ions into cells, including vascular smooth muscle and cardiac cells.
Adverse reactions of CCB's:
-GI effects (nausea, vomiting, constipation)
-excessive hypotension (causing dizziness)
-bradycardia & edema
-shortness of breath (resultant of pulmonary edema)
-nasal congestion, rhinitis
True
False
Oral manifestations of CCB's (can) include:
Gingival englargement
Xerostomia
Dysgeusia
oral thrush
CCB's are one of the few anti-hypertensive groups whose effect is NOT reduced by NSAID's.
Both nausea and constipation, both side effects of CCB's, could be additive with the side effects produced by NSAID's (i.e. ibuprofen-- nausea) and the opioids (i.e. codeine-- constipation).
Both of the statements are false.
Both of the statements are true.
The first statement is false and the second statement is true.
The first statement is true and the second statement is false.
Gingival enlargement has been reported most often with:
diltiazem
verapamil
nifedipine
none of these
