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WorksheetsMHC molecules
Total questions: 21
Worksheet time: 14mins
The antigens which are found on the membranes of almost all the cells of human body (and vertebrates) are known as
Major Histocompatibility Antigen
Major Histocompatibility Complex
Exogenous antigens (those taken up by endocytosis) are processed in the (a) and presented on the membrane with class II MHC molecules
Endogenous antigens (those generated within the cell) are processed in the (a) and presented on the membrane with class I MHC molecules;
recognize only protein antigens in the form of peptides
T cells
B cells
recognize variety of antigens (protein, polysaccharides, nucleic acids and lipids)
B-cells
T cells
The conversion of an antigen into a form in which it can be recognized by lymphocytes
Antigen processing
Antigen Presentation
The process by which certain cells in the body (antigen-presenting cells) express antigen on their cell surface in a form recognizable by lymphocytes
Antigen presentation
Antigen processing
constitutively express class II MHC molecules but must be activated before they express the co-stimulatory B7 molecule
Macrophages
B cells
Dendritic cells
must be activated by phagocytosis of particulate antigens before they express class II MHC molecules or the costimulatory B7 membrane molecule.
Dendritic cells
Macrophages
B cells
are the most effective of the antigen presenting cells. Because these cells constitutively express a high level of class II MHC molecules and co-stimulatory activity, they can activate naive TH cells
macrophages
dendritic cells
B cells
Cells that display peptides associated with class II MHC molecules to CD4+ TH cells are called
antibody
antigen-presenting cells
t cell
b cell
Cells that display peptides associated with class I MHC molecules to CD8+ TC cells are referred to as target cells
mhc
target cells
T cell receptors
b lymphocytes
Class II MHC molecules bind peptides derived from (a) that are internalized by phagocytosis or endocytosis and processed within the endocytic pathway
Class I MHC molecules bind peptides derived from (a) that have been processed within the cytoplasm of the cell
genes encode, in addition to other products, various secreted proteins that have immune functions, including components of the complement system and molecules involved in inflammation
CLASS I MHC
CLASS II MHC
CLASS III MHC
genes encode glycoproteins expressed primarily on antigen-presenting cells (macrophages, dendritic cells, and B cells), where they present processed antigenic peptides to TH cells.
CLASS I MHC
CLASS II MHC
CLASS III MHC
genes encode glycoproteins expressed on the surface of nearly all nucleated cells; the major function of the class I gene products is presentation of peptide antigens to TC cells.
Class II MHC
Class I MHC
Class III MHC
these genes are localized to a large genetic region containing multiple loci
complex
antigen
antibody
the cluster of gene was named as the _______
Major histocompatibility Complex
Major histocompatibility Antigen
A group of closely related genes was the cause of (a)
MHA are (a) in chemical nature
