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Schizophrenia

Total questions: 20

Worksheet time: 15mins

Name
Class
Date
1.

Which of the following is considered a poor prognostic factor in Schizophrenia?

a)

Late onset

b)

No precipitating factors

c)

Positive symptoms

d)

Depressive symptoms

2.

Which of the following is true regarding the modern fertility rate of people with Schizophrenia?

a)

The fertility rate is much lower than the general population

b)

The fertility rate is much higher than the general population

c)

The fertility rate is never affected by the illness

d)

The fertility rate is close to the general population

3.

A patient with a chronic mental illness on long-term treatment presents to the clinic with repetitive and persistent perioral movement and tongue protrusion, which of these medications is the likely cause?

a)

Clozapine

b)

Perphenazine

c)

Phenobarbital

d)

Diazepam

4.

The lifetime risk of suicide in schizophrenia is approximately:

a)

20-30%

b)

1%

c)

5-10%

d)

50-60%

5.

Which of the following has been found in neuroimaging studies of patients with schizophrenia?

a)

Decreased size of lateral and third ventricles

b)

Increased neocortical volume

c)

Decreased basal ganglia volume

d)

Decrease volume in the hippocampus

6.

Which of the following psychosocial interventions has been shown to reduce relapse rates in patients with schizophrenia?

a)

Social skills training

b)

Family psychoeducation

c)

Supported employment

d)

Personal therapy

7.

A 19-year-old patient begins treatment following his first episode of psychosis. His parents ask about their son’s long-term prognosis. Which of the following statements would be most accurate?

a)

Most patients achieve sustained recovery

b)

Two-thirds of patients have good outcome and only mild symptoms

c)

One in five patients achieve sustained recovery

d)

Half of patients achieve sustained recovery

8.

Which of the following pharmacological strategies increases the likelihood of sustained recovery in schizophrenia?

a)

Give medication only during periods of symptoms exacerbation

b)

Give medication as close to the onset of psychosis as possible

c)

Give two or more medications at the same time

d)

Give benzodiazepines with approved drugs for schizophrenia

9.

Which of the following symptoms is associated with worse prognosis in schizophrenia?

a)

Hallucinations

b)

Disorganization

c)

Bizarre delusions

d)

Mood lability

10.

Which of the following clinical features would be helpful in identifying co-morbid depression in a patient with prominent negative symptoms?

a)

Anhedonia

b)

Social withdrawal

c)

Affecting blunting

d)

Guilty feelings

11.

Which of the following represents the current order of stages of illness in schizophrenia?  

a)

Premorbid, prodromal, progressive, and chronic-residual

b)

Prodromal,  chronic-residual, and progressive

c)

Premorbid, prodromal, involutional, and senile

d)

Progressive, prodromal, and resistant

12.

The use of dopamine antagonists is most likely to improve which of the following symptoms of schizophrenia?

a)

Social withdrawal

b)

Stereotypes thinking

c)

Muscular rigidity

d)

Disorganization

13.

Which of the following risk factors would increase the likelihood of drug-induced hyperprolactinemia?

a)

Low potency D2 antagonism

b)

Male sex

c)

Increased age

d)

Use of aripiprazole

14.

What is the proposed mechanism for the parkinsonian side effects seen with medications used for schizophrenia?

a)

Muscurinic cholinergic receptor blockade

b)

Nigrostriatal dopamine receptor blockade

c)

Alpha1 receptor antagonism

d)

Hypothalamic histaminergic H1 receptor blockade

15.

Cognitive symptoms in schizophrenia account for much of the disability associated with the illness. Which of the following comprises two of the cognitive faculties impaired in schizophrenia?

a)

Attention, working memory

b)

Long-term memory, visuospatial construction

c)

Color perception, sensory integration

d)

Motor coordination, pain sensation

16.

Following the administration of a medication to treat agitation, a patient develops rigidity, confusion, and autonomic instability.

Which of the following agents is most likely to have caused these symptoms?    

a)

Diphenhydramine

b)

Clozapine

c)

Haloperidol

d)

Valproate

17.

A patient with schizophrenia reports that he can hear his own thoughts spoken out loud, what is the name of this psychopathology?

a)

Passivity of thought

b)

1st person auditory hallucination

c)

Thought echo

d)

Thought broadcast

18.

Which of the following medications is less likely to prolong the QTc interval?  

a)

Haloperidol

b)

Ziprasidone

c)

Droperidol

d)

Aripiprazole

19.

Which of the following is a true statement about the eye movement dysfunction in schizophrenia?  

a)

Abnormal eye movements occur more often in patients with schizophrenia than in normal controls

b)

Eye movement dysfunction is independent of drug treatment

c)

Eye movement dysfunction is seen in first degree probands

d)

All of the above

20.

Which of the following is NOT typically associated with catatonia?

a)

Mannerisms

b)

Mutism

c)

Stereotypies

d)

Verbigeration