Which of the following is a characteristic of complement?

Complement is essential for our body’s response to infection, by being heavily involved in:

Which complement component is found in both the classical and alternative pathways?

Which of the following can activate the alternative complement pathway?

Which of the following is the correct order of activation of complement in the lectin activation pathway?

The lectin pathway is initiated by the presence of which of the following?

The recognition unit in the classical complement pathway consists of:

Which of the following immunoglobulins is able to activate complement?

Which of the following functions by inserting itself into target membranes and forming channels or holes in the membranes?

The C5 convertase of the alternative pathway of complement activation is: 

C5b6789 functions in:

Which of the following acts as an opsonin?

Which complement protein is the key intermediate in all complement pathways?

Which of the following complement components has chemotactic activity?

The alternative and classical pathway C3 convertases are destabilized as a means of downregulating complement function. One molecule that performs this function is:

Formation of the membrane attack complex (C5b–C9) is stopped by which factor?

Which factor must be associated with factor H to inactivate complement components?

Lack of the complement components C5 through C9 may result in which condition?

Dense deposits of C3 breakdown products can accumulate in the kidneys because of:

Lack of the complement inhibitor C11NH results in which disease?

Kidney glomeruli can become obstructed with immune complexes as a result of:

Which of the following complement therapeutics targets the classical pathway?

Antibodies targeting C1s as therapy for cold agglutinin autoimmune hemolytic anemia would cause which of the following?

What reagent is present in a CH50 assay and absent in an AH50 assay?

A decreased CH50 and a decreased AH50 would indicate a low amount of which of the following complement components?

Select the test that could be used to determine whether a patient has a specific deficiency in C3.

A patient has an abnormal alternative pathway activation pattern. Which of the following complement proteins should be assessed to further investigate the problem?

A normal CH50 and low AH50 may indicate which of the following?

Patients undergoing treatment with complement therapeutics for hereditary angioedema (HAE) would expect to have which of the following laboratory values?

Therapeutics targeting the alternative pathway typically cause: