WorksheetsAre you a neuronerd?
Total questions: 41
Worksheet time: 21mins
Which of the following is the most common intraaxial, supratentorial tumor in adults?
Oligodendroglioma
Meningioma
Pinealoma
Glioblastoma
Which of the following biomarkers is associated with good prognosis and better therapeutic response in patients with glioblastoma?
MGMT hyper-methylation
IDH-1 and -2 phosphorylation
HDMI methylation
MGMT hypomethylation
Select an histological feature of the most common extra axial intracranial tumor
Which bacterial pathogen is the common in adolescents and young adults?
N. meningitidis
S. Pneumoniae
L. Monocytogenes
Enterovirus
Which type of cell is located between neurons and capillaries to control what enters the cells from the blood?
Astrocytes
Oligodendrocytes
Schwann cells
Satellite cells
Which two types of cells produce myelin coverings around the nerves?
Microglia and astrocytes
Schwann cells and satellite cells
Schwann cells and oligodendrocytes
Oligodendrocytes and astrocytes
This glial cell is responsible for creating the myelin for the Central Nervous System.
Neuron
Schwann cell
Oligodendrocyte
Microglia
Which neuron structure is indicated by #1 ?
Dendrite
Axon
Axon terminal
Myelin sheath
Which neuron structure is indicated by #7 ?
Dendrite
Nodes of Ranvier
Axon terminal
Myelin sheath
Sensory areas are associated with touch and temperature awareness
Frontal lobe
Temporal lobe
Parietal lobe
Occipital lobe
Association areas have been linked to emotions and interpreting speech
Frontal lobe
Temporal lobe
Parietal lobe
Occipital lobe
A 72-year-old man presents to his primary care provider for evaluation of his advanced dementia. Testing has revealed significant cell loss in his hippocampal formation. The hippocampal formation is part of which lobe?
Temporal
Occipital
Parietal
Frontal
An elderly patient presents to his audiologist for a hearing evaluation. In explaining the anatomy of the auditory system, the audiologist explains that the primary auditory cortex (Heschl’s gyrus) receives input from which
gyrus/structure?
Angular gyrus
Medial geniculate nucleus
Pulvinar
Primary auditory cortex
Patients with the severe form of this type of aphasia do not respond appropriately to questions and follow virtually no commands.
Broca
Transcortical
Wernicke
Global
From the following options, choose the one structure that does not embryologically come from the telencephalon
Subcortical white matter
Midbrain tectum
Cerebral hemispheres
Basal ganglia
What is your diagnosis?
Pilocytic astrocytoma
Ependymoma
Oligodendroglioma
Glioblastoma
What acronym can help you identify a stroke?
SLOW
FAST
STROKE
SLEEP
Which of these are risk factors for stroke?
High blood pressure
Age > 55 years
Low cholesterol
Family history of stroke
All of the above
During your discharge teaching to a patient with multiple sclerosis, you educate the patient on how to avoid increasing symptoms and relapses. You tell the patient to avoid: (select all that apply)
Cold temperatures
Infection
Overexertion
Salt
Stress
Which of the following assessment findings should the healthcare provider expect to identify as an early clinical characteristic of MS?
Muscle atrophy
Dementia
Vision loss
Clonus
What is the most common type of MS?
Secondary progressive MS
Relapsing remitting MS
Primary progressive MS
Benign
Which of the following is the most helpful study in the clinical investigation of MS?
MRI
Radiography
Visual evoked potentials
Lumbar puncture
Criteria used in the diagnosis of MS
Jones
Duke
McDonald
Select the TRUE statements about the pathophysiology of multiple sclerosis
Plaques of demyelination, disseminated in time and space, interfere with neuronal transmission
The dendrites on the neuron are overstimulated leading to the destruction of the axon.
The dopaminergic neurons in the part of the brain called substantia nigra have started to die.
You’re developing a plan of care for a patient with multiple sclerosis who presents with Uhthoff’s Sign. What interventions will you include in the patient’s plan of care?
Avoid movements of the head and neck downward
Keep room temperature cool
Encourage patient to use warm packs and heating pads for symptoms
Presence of lesions in different regions of the CNS in a patient with MS.
Dissemination in time (DIT)
Dissemination in space (DIS)
Which lobe of the human brain would be involved in vision?
Occipital
Lumbar
Parietal
Frontal
With a lesion in this cortical area (Brodmann’s), patient understands spoken word but cannot form fluent sentences.
22
44
17
3
The acute local blood flow for gray matter is:
750 ml/100g/min
75-90 ml/100 g/min
25-30 ml/100g/min
120 ml/100g/min
You are on your first clinical rotation and the attending of the neurology ward, asks you to perform a lumbar puncture (LP) on a patient who probably has an inflammatory process of meninges. You get an opening pressure of 180 cm H20, which is an abnormal result. What is the normal opening pressure when your perform an LP?
12 cm H20
6-25 cm H20
170 cm H20
30 cm H20
If a patient gets damage to this cortical area, the result will be contralateral failure of tactile recognition of objects
Parietal
Temporal
Occipital
Frontal
After the occurrence of an action potential, there is a repolarization of the membrane. The principal explanation for this event is that...
The membrane becomes impermeable to all ions
Sodium Channels have been opened
Potassium channels have been opened
Potassium channels have been inactivated
The trigger zone that integrates incoming signals from other cells and initiates the signal that the neuron sends to another neuron or muscle cell is the
Axon terminal
Dendritic trunk
Cell body
Axon hillock
This pathway of the spinal cord, conveys discriminatory touch (two-point touch), vibration, proprioception and stereognosis.
Lateral hor
Ventral horn
Posterior column
Lateral column
A 37-year-old man comes into your office with the complaint that he cannot smell. He states that several months ago he was involved in a bar fight in which his nose and several other facial bones were fractured. Ever since he was discharged from the hospital at that time, he has not been able to smell. The injury to one of the following structures is the reason for this patient clinical picture.
Inferior orbital fissure
Foramen magnum
Cribriform plate
Internal nasal valve
Sugammadex is a drug that reverses the action of rocuronium and certain other skeletal muscle-relaxing agents (steroidal neuromuscular blocking agents). It appears to interact directly with the rocuronium molecule and not at all with the rocuronium receptor. Which of the following terms best describes sugammadex?
Chemical antagonist
Noncompetitive antagonist
Partial agonist
Pharmacologic antagonist
Ampicillin is eliminated by first-order kinetics. Which of the following statements best describes the process by which the plasma concentration of this drug declines?
There is only 1 metabolic path for drug elimination
The half-life is the same regardless of the plasma concentration
The drug is largely metabolized in the liver after oral administration and has low bioavailability
The rate of elimination is always proportional to the rate of administration
The drug is distributed to only 1 compartment outside the vascular system
A 55-year-old man is seen in the clinic with hypertension of 150/95 mm Hg (millimeters of mercury). His personal medical history and physical examination are otherwise unremarkable, but his family history is positive for early deaths due to cardiovascular disease. A decision is made to treat his hypertension, starting with a calcium channel blocker. Blocker A in a dose of 5 mg produces the same decrease in blood pressure as 500 mg of blocker B. Which of the following predictions is most accurate?
Blocker A will be more efficacious than blocker B
Blocker A will be about 100 times more potent than blocker B
Toxicity of blocker A will be less than that of blocker B
Blocker A will have a wider therapeutic window than blocker B
Blocker A will have a longer half-life than blocker B
You are planning to treat chronic major depression in a 35-year-old patient with recurrent suicidal thoughts. She has several comorbid conditions that require drug therapy, including rifampin for tuberculosis and amiodarone for arrhythmia. You are concerned about drug interactions caused by changes in drug metabolism in this patient. Drug metabolism in humans usually results in a product that is:
Less lipid soluble than the original drug
More likely to distribute intracellularly
More likely to be reabsorbed by kidney tubules
More lipid soluble than the original drug
Less water soluble than the original drug
