This condition wherein the red cell is stained with various shades of blue with tinges of pink

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Percentage of RBCs that are polychromatophilic:

1%

Grading: (a)  

Percentage of RBCs that are polychromatophilic:

3%

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Percentage of RBCs that are polychromatophilic:

5%

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Percentage of RBCs that are polychromatophilic:

10%

Grading: (a)  

Percentage of RBCs that are polychromatophilic:

>11%

Grading: (a)  

This is due to combination of the affinity of hemoglobin to acid stain and the affinity of RNA to the basic dye

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Condition where in the red cells appears pale

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What are the 2 possible causes of hypochromasia

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area of central pallor is 1/2 of the cell diameter

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area of central pallor is 2/3 of the cell diameter

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area of central pallor is 3/4 of the cell diameter

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Thin rim of hemoglobin

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A condition wherein the re cell is deeply abnormal thickness of cells

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Abnormal nuclear maturation but normal cytoplasmic maturation

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Abnormal cytoplasmic maturation but normal nuclear maturation

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abnormal nuclear maturation but normal cytoplasmic maturation. Large oval shaped red cell which is 9-12 um

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red cells exhibit variation in shape

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normal cell with a biconcave shape in increase surface volume

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Acanthocytes is also known as?

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CD - small dense RBC with few irregularly spaced projections of varying length

Defect - abnormal membrane defet caused by an increase sphingomyelin and decrease in cholesterol and phospholipids

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CD - cell with irregularly spaced blunt processes, resembles crenated RBC

defect - abnormal lipid content of the membrane, caused by cell membrane deficiency

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Defect - G6PD resulting to accumulation of heinz bodies

CD - cell with eccentric vacuoles due to the plucked out heinz bodies

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Defect - ATP deficiency due to prolonged storage of anticoagulated blood.

pathologically - due to abnormal lipid content of the membrane

it has 0-30 scalloped; short projections

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cell swith central area of hemoglobin surrounded by colorless area and peripheral ring

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deficiency in cholesterol, phospholipid in the membrane and deficiency in LCAT

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Pear shaped / racket shape

Defect - abrnoaml maturation squeezing and fragmentation during splenic passage

CD - cells appear iin the shape of tearrop or pear with a single short or long protrusion

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It is caused by trauma

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Defect - abnormal membrane due to defective spectrin, deficiency in band protein 4.1

CD - oval or elliptical

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CD - small round dense cell whcih lacks the central pallor area usually mirocytic, and sphere shaped

DEFECT - spectrin deficiency & defective interaction of spectrin with other skeletal proteins

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crescent shaped cell due to abnormal aggregation of HbS which gives a tendency for the cell to assume a sickle shape

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Holly leaf appearance

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Defect - call fragmentation due to trauma caused by physical and mechanical agents

CD - irregularly, contracted cell; framented cell

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Characterized by an elongated or slit like area of central pallor

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Caused by osmotic changes due to cation imbalance

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SS - dark blue granules and filaments in cytoplasm

WS - bluish tinge throughout cytoplasm

COI - RNA

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SS - dark blue purple, fine or coarse punctate granules distributed throughout cytoplasm

WS - same with SS

COI - precipitated RNA

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SS - dark blue purple dense, round granule; usually one per cell; occasionally multiple

WS - same with SS

COI - DNA (nuclear fragment)

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SS - round, dark, blue purple granules attached to inner RBC membrane

WS - not visible

COI - dentured hemoglobin

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Irregular shape; product of denaturation; has somethin to do with hexose monophosphate shunt

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What is the difference between howell jolly bodies and heinz bodies?

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Dark staining iron granules that must be confirmed by iron stain by perl's prussian blue

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SS - rings or figures of eight

WS - blue rings or figure of eight

COI - remnant of mitotic spindle

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SS - fie, evely dispered, dark blue granules; imparts "golf ball" appearance to RBCs

WS - not visible

COI - precipitate of beta globin chins of hemoglobin

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