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WorksheetsInnate Immunity
Total questions: 60
Worksheet time: 30mins
Memory B cells are a part of the body’s:
2nd line of defense
3rd line of defense
1st line of defense
All of these
The pyrogenic response is usually part of the body’s:
2nd line of defense
3rd line of defense
1st line of defense
All of these
Humoral & Cellular immunity are part of:
Adaptive immunity
Innate immunity
Both Innate & Adaptive
The 3rd line of defense
Which of the following is NOT part of adaptive immunity:
Histamine
Antibodies
T cells
All of these are part of adaptive immunity
Which of the following is FALSE about mucous membranes?
Contain glycoproteins
Secretions have neutral pH
Found in the ear, eye, genitourinary, gastrointestinal, and respiratory tract
Are found near portals of entry and exit
Which of the following are NOT physical mechanisms used by the body to remove pathogens:
Urination
Ciliary escalator
Lysozyme
Peristalsis
Lactobacillus species in the female reproductive tract release lactosporin, an inhibitor of pathogenic E. coli colonization. Lactosporin is an:
Opportunist
Bacterioicin
Antibiotic
Probiotic
Which of the following are nonnucleated cells that do not participate in immune responses, but are targets for siderophores?
Leukocytes
Platelets
Lymphocytes
Erythrocytes
Sarah’s differential count is 12,650 WBCs/mm3. The normal range is 5,000 - 10,000 WBCs/mm3. What may this number indicate:
Bacterial infections or side effects of medications
Viral infections, pneumonia, or cancers
Ben's differential count is 630 WBCs/mm3. The normal range is 5,000 - 10,000 WBCs/mm3. What may this number indicate:
Bacterial infections or side effects of medications
Viral infections, pneumonia, or cancers
All of the following are signs of inflammation, EXCEPT:
Pain
Heat
Redness
Swelling
During inflammation, phagocytes squeeze between endothelial cells of blood vessels using:
Diapedesis
Margination
Vasodilation
Prostiglandins
Which of the following bacteria is more susceptible to the membrane attack complex (MAC):
Gram negative
Gram positive
Mycolic acid
The iron-binding protein found in RBC’s that is the normal target of bacterial siderophores is:
Hemoglobin
Ferritin
Lactoferrin
Transferrin
Cells that trigger apoptosis of host cells during viral infections and cancer:
Eosinophils
Mast cells
Natural killer cells
Dendritic cells
The antimicrobial peptide released by platelets that has a broad spectrum of activity against bacteria, fungi, viruses, and eukaryotic parasites.
Dermacidin
Defensins
Transferrins
Thrombocidin
Which organ monitors blood for microbes and toxins.
Spleen
Liver
Blood
Lymph
Phagocytes are part of BOTH the innate and adaptive immune systems.
True
False
Microbial activity is most numerous in areas with low water activity (Aw).
True
False
All three complement pathways can utilize C1-C9 proteins depending on the microbe present.
True
False
All phagocytes are forms of WBC’s.
True
False
Lack of resistance to an infection is termed immunity.
True
False
Receptors on microbial cells that bind to activators on host cells are termed TLRs
True
False
The innate system is activated by protein receptors in defensive cells which release _________; immune response regulators.
histamines
kinins
kinases
cytokines
The protective protein of the epidermis that aids in waterproofing the skin, hair, and nails is termed _______.
keratin
dermis
adipose
actin
Enzyme in water-based bodily secretions that hydrolyzes bonds in peptidoglycan:
coagulase
lysozyme
hydrolase
kinase
Bone marrow is responsible for creating the formed elements of blood via the process of ________.
lymphopoiesis
anticoagulase
hematopoiesis
coagulase
During allergic or inflammatory responses, the body’s granulocytic basophils release _________.
hematoxylin
streptolysin
histamine
coagulase
Dead cells and body fluids that collect at the site of injury indicate a ________infection.
bacterial
purulent
contaminated
viral
Interferons stimulate neighboring cells to produce viral replication inhibitors termed ________.
antibacterial proteins
antiviral proteins
interferons
anticoagulants
Glycoprotein responsible for keeping membranes moist and trapping microbes:
Tears
Blood
Mucus
Lysozyme
Second line defenses include:
Microbiota
T-cells
NK cells
WBCs
Which body response leads to a rise in temperature?
Sweating
Shivering
Which of the following is true regarding immunity?
Innate immunity has memory. It becomes more effective over time.
Adaptive immunity is specific for certain types of pathogens.
Innate immunity is only found in vertebrates.
Adaptive immunity is the first to respond to an infection
Which response time is faster?
Innate
Adaptive
Immunological memory is part of:
adaptive immunity
innate immunity
Receptors on host cells that interact with and recognize microbes:
toll-like receptors
pathogen-associated molecular pattern
adhesin
cadherin
Receptors on microbial cells that interact with host cells:
toll-like receptors
pathogen-associated molecular patterns
cadherin
adhesin
Immunity that you are born with:
adaptive
innate
Immunity that you aquire throughout your lifetime:
adaptive
innate
TLRs bound to PAMPs induce the release of _____________ (chemical messengers).
histamines
kinins
cytokines
pyrogens
Normal microbiota compete with pathogens via microbial _______.
synergism
antagonism
commensalism
parasitism
Granulocyte responsible for protecting against worms:
basophils
eosinophils
neutrophils
monocytes
Granulocyte responsible for protecting against allergic responses:
basophils
eosinophils
neutrophils
monocytes
_____________ fibers trap microbes that make it into the lymph nodes.
reticular
neutrophil
basophil
T-lymphocyte
Macrophages can be fixed or wandering.
True
False
Phagocytes digest microbes within a:
lysosome
phagocyte
phagolysosome
vacuole
Biofilms can resist phagocytosis.
True
False
Scar tissue is formed via __________.
fibrosis
parenchyma
stroma
hematopoiesis
A temperature of 37 degrees is considered a fever.
True
False
Proteins responsible for the complement system are formed in the:
heart
blood
liver
spleen
All three complement pathways trigger cytolysis, opsonization, and inflammation.
True
False
The classical pathway uses which proteins:
c1, c2, c3, & c4
c2, c3, & c4
c3
c3, c5, c6, c7, c8, c9
c3 & c5
The lectin pathway uses which proteins:
c1, c2, c3, & c4
c2, c3, & c4
c3
c3, c5, c6, c7, c8, c9
c3 & c5
The alternative pathway uses which proteins:
c1, c2, c3, & c4
c2, c3, & c4
c3
c3, c5, c6, c7, c8, c9
c3 & c5
The opsonization pathway uses which proteins:
c1, c2, c3, & c4
c2, c3, & c4
c3
c3, c5, c6, c7, c8, c9
c3 & c5
The cytolysis pathway uses which proteins:
c1, c2, c3, & c4
c2, c3, & c4
c3
c3, c5, c6, c7, c8, c9
c3 & c5
The inflammation pathway uses which proteins:
c1, c2, c3, & c4
c2, c3, & c4
c3
c3, c5, c6, c7, c8, c9
c3 & c5
Chemotactic factors:
allow motility
attract phagocytes to an infection
break down therapeutic drugs
reduce fevers
____________ warn host cells of a viral infection.
Interferons
Phagocytes
Neutrophils
Eosinophils
