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WorksheetsYear 1 Case 8 revision
Total questions: 14
Worksheet time: 9mins
Which layers undergoes the terminal differentiation process of keratinisation?
A
B
C
D
E
Which layers is only present in the sole of palms and feet's?
A
B
C
D
E
Which of the following best characterizes sebaceous glands?
Its duct drains onto the skin surface
It releases its contents via holocrine secretion
It primarily secretes protein-riched sebum
Its secretory units are supplied by adrenergic stimulation
It is located typically in the reticular dermis
A 17-year-old sixth-form student has several open and closed comedones mostly across his cheeks and chin. He also complains of painful papules on his back. Which of the following is the most appropriate treatment to commence?
Topical benzoyl peroxide with oral erythromycin
Topical benzoyl peroxide with clindamycin
Topical azelaic acid with oral doxycycline
Topical benzoyl peroxide only
Topical adapalene with benzoyl peroxide with oral doxycycline
Which of the following is bacteriostatic?
Peptidoglycan synthesis inhibition
Peptidoglycan cross-linking inhibition
Bacterial DNA damage
Cell-membrane pore formation
Protein synthesis inhibition
A 25 yo woman complains of dysuria and and urgency. Her urine is particularly foul-smelling. UTI is suspected and 3-day course of antibiotics which is known to inhibit dihydrofolate reductase is prescribed. Which type of antibiotic is being described?
Rifampicin
Trimethoprim
Clarithromycin
Amoxicillin
Doxycycline
A 46-year-old male was diagnosed with Mycoplasma pneumonia . He was started on first-line antibiotic therapy. Despite the use of antibiotic medication for 5 days, his fever and cough did not subside. Which of the following is a plausible means by which the patient failed to improve with treatment?
Alteration of the pentapeptide side chain of N-acetylmuramic acid
Increased efflux of the bacteria by plasmid-encoded transport pumps
Mutation of the gene for DNA gyrase
Production of an enzyme that cleaves β- lactam structures
Methylation of the 23S ribosomal RNA
Which of the following correctly described the pathophysiology of sepsis?
Pro-inflammatory cytokines accelerates apoptosis
Increase vascular tone leads to decrease capillary pressure
Vasoconstriction causes capillary leakage
Release of reactive oxygen species damages endothelium leading to decrease permeability
Release of nitric oxide causes vasodilation and leads to hypotension
41-year-old women had a surgery 2 days ago. Her respiratory rate has risen from 12/min to 26/min in the last 24 hours and her heart rate has risen from 62/min to 98/min in the same time period. Her urine output is reduced. She is apyrexial. The nurse has started her on oxygen and is setting up a fluid bolus. An arterial blood gas shows:
What is the next most appropriate step?
Blood culture
Broad spectrum oral antibiotics
CRP
CPAP mask
WBC count and differentials
Which of the following condition is most commonly caused by staphylococcus aureus?
Meningitis
Otitis media
Pharyngitis
Scaled skin syndrome
Sinusitis
Which of the following condition is most commonly caused by streptococcus pyogenes?
Meningitis
Pneumonia
Rheumatic fever/ strep throat/ pharyngitis
Sepsis
Sinusitis
What are the similarities in pathogenicity factors between Staphylococcus Aureus and Streptococcus Pneumoniae?
Fibronectin binding protein
Autolysins
Capsule
Protein A
Streptokinases
Select the statement that correctly describes sweat production.
Sweat is released in response to parasympathetic efferents releasing acetylcholine onto M3 receptors
In the secretory component of sweat production, the sweat secreted is hypotonic to plasma
In the absorptive component of sweat production, Na+ and Cl- are secreted via ENaC and CFTR channels to concentrate the sweat
Sweat has a cooling effect because the lowest energy water molecules evaporate first
Sweat forms part of insensible fluid loss
Select the antibiotic which exerts its action by inhibiting DNA gyrase
Cephalosporins
Fusidic acid
Erythromycin
Trimethoprim
Metronidazole
