WorksheetsToxic Responses to Kidney II
Total questions: 10
Worksheet time: 5mins
The target of acetaminophen-induced renal injury is
Distal tubule
Proximal tubule
Glomerulus
Loop of Henle
The following nephrotoxicants were discussed in the lecture EXCEPT?
NSAIDs
Contrasting agents
Cancer therapeutics
Drugs of abuse
The folllowing substances cause hemodynamic alteration EXCEPT:
NSAIDs
Amphotecerin B
Contrasting agemts
Lithium
The following is FALSE regarding the mechanism of drug-induced nephrotoxicity:
Altering intraglomerular hemodynamics
Increasing GFR
Tubular cell toxicity
Inflammation
Overdose of acetaminophen causes accumulation of toxic metabolite
mercapturic aicd.
glutathione.
cysteine.
N-acetyl-p-benzoquinone-imine.
Cyclosporine-induced nephrotoxicity may dsplay the following EXCEPT:
acute reversible renal dysfunction
acute vasculopathy
nephrolithiasis
chronic nephropathy with interstitial fibrosis
The followings are symptoms of acute kidney injury:
I. swelling in legs
II. fatigue
II. confusion
IV. seizures
I and II
II and III
I, II and III
All of the above
The standard battery of noninvasive tests includes:
I. measurement of urine volume
II. measurement of osmolality
III. measurement of pH
IV. measurement of urinary composition
I and III
I and IV
I, III and IV
All of the above
The followings suggest adverse reaction of drug-induced nephrotoxicity:
I. Low systolic blood pressure
II. Low urea-to-creatinine ratio
III. DecreaseI renal flow blood flow
IV. Decrease estimated glomerular filtrate rate
I and IV
I and III
II and III
None of the above
The followings are nephrotoxic::
I. fluoxetine
II. penicillin
III. ibuprofen
IV. niacin
I and II
I and III
I, II and III
All of the above
