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WorksheetsWellness and Disease Prevention Final Exam Objectives
Total questions: 86
Worksheet time: 46mins
Which of these are EPA Class A Carcinogen (causes cancer in patients)?
Smoke
Particulate Phase
Nicotine
Which of these impairs oxygen transport and utilization?
Carbon monoxide
Hydrocyanic acid, acetaldehyde, acrolein, ammonia, formaldehyde, oxides of nitrogen
Nitrosamines, Hydrazine
Which of these are carcinogens?
Carbon monoxide
Hydrocyanic acid, acetaldehyde, acrolein, ammonia, formaldehyde, oxides of nitrogen
Nitrosamines, Hydrazine
The particulate phase is mostly?
Smoke
Carcinogens
Nicotine
What does Nicotine do to metabolism?
Increase
Decrease
Has no effect
When recalling the pharmacokinetics of pharmacology of nicotine and mechanism of tobacco dependence what is the pKa of Nicotine?
8
9
7
6
5
Absorption of nicotine from the respiratory tract, buccal mucosa and skin depends on the ___ of the nicotine delivery vehicle.
pH
Surrounding tissue
Lipophilicity
Pleasure, suppressive appetite
Dopamine
Acetylcholine
Serotonin
Norepinephrine
Vasopressin
Arousal, cognitive enhancement
Dopamine
Acetylcholine
Serotonin
Norepinephrine
Vasopressin
Mood modulation, suppress appetite
Dopamine
Acetylcholine
Serotonin
Norepinephrine
Vasopressin
Memory Improvement
Dopamine
Acetylcholine
Serotonin
Norepinephrine
Vasopressin
Arousal, suppress appetite
Dopamine
Acetylcholine
Serotonin
Norepinephrine
Vasopressin
Reduce Anxiety/Tension
Dopamine
Beta-endorphin, GABA
Serotonin
Norepinephrine
Vasopressin
Select all that apply: Which of these are signs and symptoms of nicotine withdrawal?
Perspiration, hypersalivation, palpitation, pallor, tremor
Insomnia, restlessness, anxiety, fatigue
Dizziness, hearing/visual disturbances, confusion, weakness
Decreased HR
Increased appetite/weight gain
Select all that apply: Which of these are signs and symptoms of nicotine toxicity?
Perspiration, hypersalivation, palpitation, pallor, tremor
Insomnia, restlessness, anxiety, fatigue
Dizziness, hearing/visual disturbances, confusion, weakness
Decreased HR
Increased appetite/weight gain
Nausea, vomiting and diarrhea is associated with:
Nicotine Withdrawal
Nicotine Toxicity
Dysphoric or depressed mood is associated with:
Nicotine Withdrawal
Nicotine Toxicity
Sweating or increased skin temperature is associated with:
Nicotine Withdrawal
Nicotine Toxicity
Gastrointestinal disurbance is associated with:
Nicotine Withdrawal
Nicotine Toxicity
The patient currently has no intention to quit in the next 6 months.
Precontemplation
Contemplation
Preparation
Action
Maintenance
The patient is considering quitting in the next 6 months but has no definite plans.
Precontemplation
Contemplation
Preparation
Action
Maintenance
The patient is planning on quitting in the next month and has attempted to quit in the last 12 months or have made small behavioral changes.
Precontemplation
Contemplation
Preparation
Action
Maintenance
The patient has abstained from smoking for one day to 6 months.
Precontemplation
Contemplation
Preparation
Action
Maintenance
The patient has abstained from smoking for at least 6 months
Precontemplation
Contemplation
Preparation
Action
Maintenance
Which of these impairs oxygen transport and utilization?
Carbon monoxide
Hydrocyanic acid, acetaldehyde, acrolein, ammonia, formaldehyde, oxides of nitrogen
Nitrosamines, Hydrazine
What is the first step in assessing the motivational level to quit?
Precontemplation
Contemplation
Preparation
Action
Maintenance
What is the 2nd step in assessing the motivational level to quit?
Precontemplation
Contemplation
Preparation
Action
Maintenance
What is the 3rd step in assessing the motivational level to quit?
Precontemplation
Contemplation
Preparation
Action
Maintenance
What is the 4th step in assessing the motivational level to quit?
Precontemplation
Contemplation
Preparation
Action
Maintenance
What is the 5th step in assessing the motivational level to quit?
Precontemplation
Contemplation
Preparation
Action
Maintenance
True or false: One may relapse up to 11 times before staying quit
True
False
Which of the 5A's asks about the history of smoking in the family?
Ask
Advise
Assess
Assist
Arrange
Which of the 5A's talks about the health hazards of current behavior using motivational interviewing techniques?
Ask
Advise
Assess
Assist
Arrange
Which of the 5A's looks at the current commitment to consider changing unhealthy behavior?
Ask
Advise
Assess
Assist
Arrange
Which of the 5A's develops a plan to self manage, change and move toward healthy behavior?
Ask
Advise
Assess
Assist
Arrange
Which of the 5A's follows up to support success and refers to local and national resources?
Ask
Advise
Assess
Assist
Arrange
How often should you ask about tobacco use?
Every visit
3 months
6 months
Every year
Which of the 5A's talks about tobacco use for every patient?
Ask
Advise
Assess
Assist
Arrange
Which of the 5A's talks to patients about quitting. Individually tailoring messages to patients to explain the benefits of discontinuing smoking?
Ask
Advise
Assess
Assist
Arrange
Which of the 5A's talks to patients about willingness to quit smoking at this point in time?
Ask
Advise
Assess
Assist
Arrange
Which of the 5A's sets up a follow up on a date to increase the likelihood of success?
Ask
Advise
Assess
Assist
Arrange
Which of the 5 R's to motivate smokers to quit smoking does this apply to: encourage self reflection to establish discrepancy
Relevance
Risks
Rewards
Roadblocks
Repetition
Which of the 5 R's to motivate smokers to quit smoking does this apply to: Encourage the person to reflect on negative consequences of tobacco use
Relevance
Risks
Rewards
Roadblocks
Repetition
Which of the 5 R's to motivate smokers to quit smoking does this apply to: identify benefits of stopping smoking
Relevance
Risks
Rewards
Roadblocks
Repetition
Which of the 5 R's to motivate smokers to quit smoking does this apply to: encourage patient to think about and discuss barriers to quitting
Relevance
Risks
Rewards
Roadblocks
Repetition
Which of the 5 R's to motivate smokers to quit smoking does this apply to: repeat personalized motivational interview at each encounter
Relevance
Risks
Rewards
Roadblocks
Repetition
What is the rationale for nicotine replacement therapy (NRT)?
Relieve or prevent nicotine withdrawal symptoms in order to allow the patient more time to focus/modify their smoking behavior and psychological aspects
NRT does not expose the patient to the carcinogens and other toxic components of cigarette smoke
NRT provides lower, slower and less variable plasma nicotine concentration
Nicotinic acetylcholine receptor agonist or replacement
Which are some precautions that are associated with NRTs?
Serious arrythmias
Angina pectoris
Unstable angina
COPD
SOB
What are some contraindications of NRT?
Continued use of tobacco or other nicotine containing products
Active temporomandibular joint disease
Cancer
Diabetic
CKD
Nicotine Polacrilex gum (Nicorette, Generic) comes in which doses?
2mg
4mg
10mg
20mg
If a pt smokes <25 cigs/day or Fagerstrom <7 or 1st cig >30 mins after waking which dose should they be on?
2mg
4mg
7mg
5mg
10mg
If a pt smoke >25 day OR Fagerstrom >7 OR 1st cig <30 min after waking
2mg
4mg
7mg
5mg
10mg
When using Nicotine Polacrilix Gum (Nicorette, Generic) furing the weeks 1-6 how often should patient chew one piece of gum?
1-2 hours
2-4 hours
4-8 hours
When using Nicotine Polacrilix Gum (Nicorette, Generic) during the weeks 7-9 how often should patient chew one piece of gum?
1-2 hours
2-4 hours
4-8 hours
When using Nicotine Polacrilix Gum (Nicorette, Generic) during the weeks 10-12 how often should patient chew one piece of gum?
1-2 hours
2-4 hours
4-8 hours
True or false: Pts should avoid eating/drinking acidic beverages after using chewing gum by 15 minutes
True
False
What doses does Nicotine Polacrilix Patch (Nicoderm CQ, Generic) come in?
7mg
14mg
21mg
2mg
4mg
What doses does Nicotine Polacrilix Patch (Nicoderm CQ, Generic) NOT come in?
7mg
14mg
21mg
2mg
4mg
If a patient wants to be on the patch and smokes <10 cig/day which step program should they be on?
2 steps → 14mg/24hr patch for 6 weeks (GEN and CQ), then 7mg patch for 2 weeks
3 steps → 21mg/24 hr patch for 4 (GEN)-6 (CQ) weeks, then 14mg/24hr for 2 wk, then 7mg for 2 weeks
4 Step program --> 21mg/24 hours patch for 6 weeks
If a patient wants to be on the patch and smokes >10 cig/day which step program should they be on?
2 steps → 14mg/24hr patch for 6 weeks (GEN and CQ), then 7mg patch for 2 weeks
3 steps → 21mg/24 hr patch for 4 (GEN)-6 (CQ) weeks, then 14mg/24hr for 2 wk, then 7mg for 2 weeks
4 Step program --> 21mg/24 hours patch for 6 weeks
What is the recommended initial dosing of Nicotine Patch Therapy for those that smoke <10 cigarettes per day?
7mg-14mg/day
14mg-22mg/day
22-44mg/day
44mg/day
What is the recommended initial dosing of Nicotine Patch Therapy for those that smoke 10-20 cigarettes per day?
7mg-14mg/day
14mg-22mg/day
22-44mg/day
44mg/day
What is the recommended initial dosing of Nicotine Patch Therapy for those that smoke 21-40 cigarettes per day?
7mg-14mg/day
14mg-22mg/day
22-44mg/day
44mg/day
What is the recommended initial dosing of Nicotine Patch Therapy for those that smoke >40 cigarettes per day?
7mg-14mg/day
14mg-22mg/day
22-44mg/day
44mg/day
What is the dosing for Nicotine Polacrilix Lozenge (Nicorette Mini and Standard)?
2mg
4mg
7mg
21mg
14mg
What is the dosing for Nicotine Polacrilix Lozenge (Nicorette Mini and Standard) if a patient smokes 1st cig >30mins after waking?
2mg
4mg
7mg
21mg
14mg
What is the dosing for Nicotine Polacrilix Lozenge (Nicorette Mini and Standard) if a patient smokes 1st cig <30mins after waking?
2mg
4mg
7mg
21mg
14mg
True or false: It takes 10 minutes for lozenge to completely dissolve.
False
True
True or false: It takes 20-40 minutes for lozenge to completely dissolve.
False
True
What is the dosing for Nicotine Polacrilix Lozenge (Nicorette Mini and Standard) in the weeks 1-6 one lozenge ever ___ hours?
1-2 hours
2-4 hours
4-8 hours
10-12 hours
Every 24 hours
What is the dosing for Nicotine Polacrilix Lozenge (Nicorette Mini and Standard) in the weeks 7-9 one lozenge ever ___ hours?
1-2 hours
2-4 hours
4-8 hours
10-12 hours
Every 24 hours
What is the dosing for Nicotine Polacrilix Lozenge (Nicorette Mini and Standard) in the weeks 10-12 one lozenge ever ___ hours?
1-2 hours
2-4 hours
4-8 hours
10-12 hours
Every 24 hours
In which of these situations are lozenges being used INCORRECTLY?
>5 lozenges in 6 hours
>20 lozenges/day
>12 weeks of therapy
11 weeks of therapy
True or false: Doubling up on lozenges can increase efficacy.
False
True
What dose does Bupropion (Zyban) come in?
150mg
2mg
4mg
10mg
What is the max dose of Bupropion?
150mg
10mg
300mg
4mg
What dose does Chantix (Varenicline) come in?
150mg
2mg
1mg
4mg
0.5mg
When using titrations for patient on Chantix (Varenicline) what is the schedule for those on Day 1-3?
0.5mg PO daily
0.5mg BID
1mg BID
When using titrations for patient on Chantix (Varenicline) what is the schedule for those on Day 4-7?
0.5mg PO daily
0.5mg BID
1mg BID
When using titrations for patient on Chantix (Varenicline) what is the schedule for those on Day 8-12?
0.5mg PO daily
0.5mg BID
1mg BID
When should you refer patient to MD before recommending OTC NRT to patients?
Under 18 y/o
CV disease
HTN isn't controlled
On depression or asthma medication
Pregnant / breastfeeding
When should you refer patient to MD before recommending OTC NRT to patients?
Have active peptic ulcers
Hyperthyroidism
Hormone secreting tumors
Numerous attempts of failed attempts using monotherapy
Pregnant / breastfeeding
JA, a 22-year-old college student, has been encouraged by her family pharmacist to stop smoking. She tells her family pharmacist that she wants to quit, but she does not want to gain weight right now or to sacrifice her grades as a result of an inability to concentrate during the day. According to the 5 A’s strategy and the Transtheoretical model of change, what is the next step JA’s family pharmacist should take?
JA is in the precontemplation stage. Her family pharmacist should reassess her willingness to quit at the next visit.
JA is in the contemplation stage. Her family pharmacist should reassess her willingness to quit at the next visit.
JA is in the preparation stage. Her family pharmacist should reassess her willingness to quit at the next visit.
JA is in the preparation stage. Her family pharmacist should offer her counseling and/or pharmacologic therapy for smoking cessation.
Because of the risk of nicotine toxicity, smokers who desire to quit smoking should be strongly advised to stop smoking when nicotine-replacement therapy is used. Patients who still smoke with the use of nicotine-replacement therapy may develop signs of nicotine toxicity. These signs include:
1) Insomnia, palpitation, and vivid dreams.
2) Hypersalivation, nausea, vomiting, and diarrhea.
3) Anger, anxiety, frustration, difficulty concentrating, and restlessness.
1
3
1,2
2,3
1,2,3
How to differentiate from insomnia of nicotine withdrawal?
Increase awakening at night means you need to increase dose
Decrease awakening at night means you need to increase dose
What component in cigarettes cause drug interactions, CYP450, 1A2 inducers?
Polycyclic aromatic hydrocarbon
Epoxide
OH group
Sulfur group
