WorksheetsGIT Pharmacology
Total questions: 13
Worksheet time: 8mins
Regarding drugs used in the treatment of inflammatory bowel diseases:
5-amino salicylic acid of sulfasalazine undergoes complete absorption in the stomach.
Prolonged glucocorticoid therapy is given to maintain remission.
Infliximab helps to close fistulas in Crohn’s disease.
Azathioprine is a purine analogue.
Methotrexate causes mucosal ulcerations.
Omeprazole reduces gastric acidity by reversible blockade of the H+/K+-ATPase.
True
False
Calcium carbonate reduces gastric acidity by reducing the Ca++ content in parietal cells.
True
False
Ranitidine reduces only stimulated gastric acidity by inhibiting H2-receptors on parietal cells.
True
False
Misoprostol reduces gastric acidity by neutralizing gastric HCl.
True
False
Colloidal bismuth subcitrate reduces gastric acidity by coating the ulcer crater.
True
False
The antidiarrhoeal agent is CORRECTLY matched to its clinical use:
Oral rehydration salts (ORS) = Non-infective diarrhoea
Loperamide = Secretory diarrhoea
Octreotide = Traveller's diarrhoea
Carboxymethyl-cellulose = Bile acid-induced diarrhoea
Cholestyramine = Secretory diarrhoea
A 38-year-old Filipino woman presented with multiple subcutaneous nodules and headaches. She was born in San Jose, Mindoro and had been a pork and beef vendor for nine years but denied having ingested raw or inadequately cooked meat. Stool examination showed Ascaris lumbricoides and Trichuris trichiura ova.
Which antihelminthic agent is the BEST CHOICE for therapy?
Praziquantel
Niclosamide
Piperazine
Albendazole
The combination of erythromycin and lincosamide is synergistic as both antibiotics are bacteriostatic.
True
False
Cimetidine increases the plasma concentration of theophylline due to the displacement of theophylline from protein binding sites.
True
False
NSAIDs antagonize the effect of diuretics because NSAIDs reduce renal blood flow.
True
False
Sodium bicarbonate reduces noradrenaline's efficacy if they are mixed together in one syringe before administration/injection.
True
False
Phenobarbital increases the risk of bleeding by warfarin due to phenobarbital's CYP450 inhibition.
True
False
