WorksheetsQ2 Exam 1 Practice
Total questions: 20
Worksheet time: 10mins
Type I diabetes can result in ketoacidosis. All of the following can be an explanation for a high level of ketone bodies EXCEPT:
high levels of free fatty acids in blood
over production of HMG-CoA
carnitine deficiency
too much acetyl-CoA produced by liver
Which of the following pancreatic enzymes cleaves a peptide after serine?
carboxypeptidase A
trypsin
elastase
chymotrypsin
What is the preferred substrate for hormone-sensitive lipase?
glycerol-3-phosphate
triacylglycerol
acetyl-CoA
diacylglycerol
What are the primary products of the action of pancreatic lipase on phosphatidylcholine?
glycerol and 3 fatty acids
2-monoacyl glcycerol and 2 fatty acids
glycerylphosphoryl-choline
and 2 fatty acids
glycerylphosphoryl-choline
and 1 fatty acid
The term ketogenic amino acids implies:
will not be converted either to fatty acids or ketone bodies
can yield acetoacetate or acetyl-CoA after degradation
can yield pyruvate, alpha-ketoglutarate, and oxaloacetate
are precursors for the synthesis of glucose
N-acetylglutamate (NAG) serves what function in the urea cycle?
it is a coenzyme for glutamate dehydrogenase
it degrades into acetyl-CoA and glutamate
it is an allosteric activator of carbamoyl phosphate synthetase I (CPS I)
it is an allosteric activator of glutamine synthetase
What are the steps in beta oxidation?
oxidation hydration oxidation transferase
oxidation dehydration reduction transferase
reduction hydration reduction
lyase
oxidation
lyase
oxidation
ligase
Progesterone is synthesized from:
cholesterylesters
cortisol
pregnenolone
testosterone
In the following reaction, which component is the reducing agent?
Oxaloacetate + NADH --> Malate + NAD+
oxaloacetate
NADH
NAD+
malate
Pyruvate can be formed by the removal of an amino group from which of the following amino acids?
alanine
glycine
aspartate
glutamate
Lipoprotein with the highest level of triacylglycerol:
VLDL
HDL
LDL
chylomicrons
Which of the following is NOT a common transamination pair?
aspartate/oxaloacetate
alanine/pyruvate
tyrosine/fumarate
glutamate/alpha-ketoglutarate
Which of the following is NOT used in beta oxidation?
NADPH
FAD
H2O
NAD+
Synthesis of heme begins with:
poryphobilinogen
glycine and succinyl-CoA
histidine and acetyl-CoA
histidine and succinyl-CoA
An essential amino acid:
valine
proline
glutamate
glutamine
Process by which an amine is removed as free ammonia while producing an alpha-keto acid:
peptidase cleavage
transamination
reductive amination
oxidative deamination
This is NOT a ketone body produced from beta oxidation of fatty acids:
acetone
acetoacetate
beta-hydroxybutyrate
acetate
Enzyme that cleaves before arginine:
trypsin
carboxypeptidase
B
chymotrypsin
pepsin
Deficiency of tyrosine hydroxylase could result in _____ deficiency:
serotonin
tyrosine
dopamine
fumarate
Why is lactic acidosis expected in individuals with dihydrolipoyl dehydrogenase (E3)-deficient maple syrup urine disease?
BCAAs are catabolized primarily by peripheral tissues where lactate increases
BCKD causes an accumulation of ketogenic BCAAs
oxidative decarboxylation of leucine leads to alpha-ketoisocaproic acid
lactate increases because of reduced activity of PDH complex
