Worksheets2009PHM QuizIZZ 3
Total questions: 27
Worksheet time: 9mins
Which of the following is NOT a feature of cardiovascular risk charts?
age
Aboriginal and Torres Strait Islander populations
diabetes
blood glucose
Which of the following means tissue death?
thrombosis
embolus
endothelialisation
infarction
Angiotensin II is a hormone that can cause
vasoconstriction
diuresis
vasodilation
angina
The receptors on smooth muscle cells in blood vessels that are involved in vasoconstriction are
α1
β1
α2
β2
Which of the following is NOT a plasminogen activator drug?
reteplase
delteplase
alteplase
tenecteplase
The drug prazosin helps to reduce
vessel peripheral resistance
heart rate
α1 receptor antagonism
angina attacks
Which of the following is NOT an ACE inhibitor?
daptopril
ramipril
enalapril
perindopril
ACE is an enzyme that is also known to degrade
angiotensin II
angiotensin I
the angiotensin receptor AT1
bradykinin
The "sartan" drugs such as candesartan
bind to the AT2 receptor in smooth muscle cells
are highly selective for blocking the AT1 receptor
convert angiotensin II to angiotensin I
cause vasoconstriction and increased aldosterone release
Drugs that cross the blood brain barrier and activate α2 receptors include
clonidine synthase
diltiazem
methyldopa
eplerenone
Which of the following are synthesised by aldosterone binding as an agonist to the mineralocorticoid receptor?
ENaC channels
K+ channels
Na+/K+/ATPase antiporters
Na+/K+/2Cl- symporters
Na+/Cl- symporters
HARD! Name 4 drugs in order of dihydropyridine, non-dihydropyridine, dihydro, then non-dihydro
amlodipine, diltiazem, nifedipine, verapamil
nifedipine, verapamil, diltiazem, amlodipine
amlodipine, verapamil, diltiazem, nifedipine
diltiazem, amlodipine, verapamil, nifedipine
An arterial vasodilator that would be used in heart failure would be
isosorbide mononitrate
ivabradine
isosorbide dinitrate
hydralazine
Which drug lowers plasma triglyceride levels by increasing expression of lipoprotein lipase?
Atorvastatin
Niacin
Fenofibrate
Ezetemibe
Which of the following binds directly to a single site of thrombin?
bivalirudin
dabigatran
fondaparinux
Factor VII
The levels of which of the following is decreased following warfarin treatment?
VKOR enzyme
INR
oxidised Vitamin K
activated Vitamin K
Which of the following reverses the action of heparin?
phytomenadione
protamine sulfate
fresh frozen plasma
prothrombin concentrate
Neprilysin degrades vasoactive peptides that dilate blood vessels. What drug can be used to inhibit it?
sacubritil
sotolol
candesartan
valsartan
bradykinin
For the drug combination "ARNi", which drug must be stopped 36 hours before starting this medication?
ACE inhibitor
A sartan drug
A β-blocker
All antibiotics
Ferrous sulphate
Are you ready for a DOUBLE POINTS round?
Yes
No
Maybe
I'm a bit scared now
Select any of the following β-blocker drugs that can be used in heart failure:
bisoprolol
nebivolol
carvedilol
metoprolol
propranolol
Which class of drugs does empagliflozin belong to?
SGLT2 inhibitors
ACE inhibitors
Diuretics
Aldosterone antagonists
Calcium channel blockers
Aldosterone, and aldosterone antagonist drugs, fight for binding of which receptor?
Mineralocorticoid
Glucocorticoid
Angiotensin-converting enzyme
β1
α2
On cardiac smooth muscle cells, which exchanger becomes MORE active as a result of digoxin treatment?
Ca2+/Na+
Ca2+/K+
Na+/K+/ATPase
ENaC
Na+/K+/2Cl-
Which of the following drug combinations are used for vasodilation in heart failure treatment?
Ivabradine-ACEi
isosorbide mononitrate-ivabradine
isosorbide dinitrate-hydralazine
isosorbide dinitrate-ivabradine
ivabradine-hydralazine
Are you ready for the final, TRIPLE POINTS, question?
Yes
No
Maybe
Now I'm REALLY scared :)
Select ANY of the following that apply to the use of ivabradine in heart failure treatment:
Patient must be in sinus rhythm
Patient has HR >70bpm while on a β-blocker
It reduces HF hospitalisations
It reduces cardiovascular deaths
It blocks glucose reabsorption in the kidneys
