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WorksheetsIQ 2 Hassan
Total questions: 24
Worksheet time: 9mins
Which of these is least likely to predispose one to skin cancer?
HIV
Aging
UV-B
Silica exposure
What is the most common skin cancer?
Basal Cell Carcinoma
Squamous Cell Carcinoma
Transitional Cell Carcinoma
Melanoma
Which of the following cancer(s) rarely metastasize?
Squamous Cell Carcinoma
Basal Cell Carcinoma
Superficial Spreading Melanoma
Merkel Cell Carcinoma
Characterize the lesion
Basal cell carcinoma
Marjolin ulcer
Squamous cell carcinoma
Dysplastic Nevi
If you are at risk for skin cancer, you should
Use lotion (SPF>=30)
Stay away from the sun
Visit your doctor frequently
What is the pathophysiology behind Xeroderma Pigmentosum?
Autoimmune reaction of IgG antibodies against host keratinocyte basement membrane
Type 4 hypersensitivity reaction against 1,3 calciferol
Defective nucleotide excision repair
Impaired lysosomal function
What is a sentinel lymph node?
The lymph node most distal to the primary tumor on the first branch
The lymph node most distal to the primary tumor on the second branch
The lymph node contralateral to the primary tumor
The lymph node most proximal to the primary tumor
Which of the following is the second leading cause of skin cancer deaths?
Merkel Cell Carcinoma
Squamous Cell Carcinoma
Melanoma
Basal Cell Carcinoma
The purpose of Mohs surgery is to
Assess lymph node involvement
Utilize minimally invasive surgery to prevent disfiguring scars
Minimize remission through additional debridement
Cost-effectively biopsy the primary tumor
What is/are the function(s) of a Merkel Cell?
Mechanoreception
Proprioception
Nociception
Thermoception
Risk of Merkel Cell Carcinoma Increases with
Having an XY genotype
Being over the age of 50
Hypopigmentation
previous history of skin cancer
P53 induces apoptosis by which of the following mechanisms?
Stabilizing BCl-2
Leaking Cytochome C
Upregulating BAX
None of these answers
Which of the following tumor markers is specific for Merkel Cell Carcinoma?
Cytokeratin-7
Cytokeratin-20
Chromogranin-A
CDK-21
Rb-1 exerts its effect by
De-phosphorylating Protein Kinase A
inhibiting E2F
Stabilizing BCl-2
Binding to the FC portion of IgM
T1N1M1 is:
Stage 1 Cancer
Stage 2 Cancer
Stage 3 Cancer
Stage 4 Cancer
T2N1M0 is
Stage 1 cancer
Stage 2 cancer
Stage 3 cancer
Stage 4 cancer
Which of the following drugs binds PD-1 receptor to prevent it from binding PD-L1?
Evolocumab
Pembrolizumab
Arifozumab
Infliximab
Merkel Cell Carcinoma is most responsive to
Radiation Therapy
Chemotherapy
Which of the following neuroendocrine markers is NOT found in Merkel cell carcinoma?
CD56: NCAM
Chromogranin-A
Synaptophysin
Cytokeratin 7
What is a key feature of this slide?
S-100 stain
Keratin Pearls
Palisading Nuclei
Chromogranin-A
What is this?
Basal cell Carcinoma
Actinic Keratosis
Keratoacanthoma
Dysplastic Nevus
MCPy
Melanoma-like Cellular Polyomavirus
Merkel Cell Polyomavirus
Magnesium-Chelating Polyomavirus
Mechanoreceptor Cytoplasmic Polyomavirus
In which layer of the skin are Merkel cells found?
Stratum Spinosum
Stratum Granulosum
Stratum Lucidum
Stratum Basalis
About what percentage of people who had skin cancer will be diagnose with a second one within 10 years?
3%
20%
35%
60%
