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Pathology Introduction I

Total questions: 15

Worksheet time: 13mins

Name
Class
Date
1.

General pathology is concerned with the reactions of organs and the organ system level to abnormal stimuli and to inherited defects.

a)

True

b)

False

2.

Who is the father of modern pathology?

a)

Rudolf Virchow

b)

Louis Pasteur

c)

Hippocrates

d)

Robert Koch

e)

Antonie van Leeuwenhoek

3.

A disability is any impairment of the body or mind that...

a)

a person can sense.

b)

must be supported by objective data.

c)

limits a person's ability to engage in certain tasks or actions.

d)

all of these are correct

4.

What is the meaning of the term cellular pathology?

a)

Diseases only occur in the cellular level.

b)

Virtually all forms of disease start with molecular or structural alterations in cells.

c)

The cell is essentially the source of most illnesses.

d)

None of these.

5.

Which of the following refers to the statement of what the expected outcome of a condition is likely to be?

a)

Pathogenesis

b)

Etiology

c)

Clinical manifestation

d)

Prognosis

6.

A person's mood, emotions, and personality are all aspects of his social well-being that has to be nurtured to maintain a healthy constitution.

a)

True

b)

False

7.

Encoded in a person’s DNA sequences will be his susceptibility to certain diseases, hence changes in any of the 3.2 billion DNA base pairs in the human genome can alter the function of the cells and the person’s likelihood to develop a particular illness.

a)

True

b)

False

8.

Absolute insulin deficiency occurs with autoimmune destruction of insulin secreting β-cells and other congenital conditions such as genetic defects in the formation or function of the endocrine pancreas.

This statement refers to which of the 4 cores of pathology?

a)

Etiology

b)

Pathogenesis

c)

Morphologic Changes

d)

Functional Changes

e)

Clinical Manifestation

9.

Patients with diabetes mellitus often experience polyuria, increased thirst, dehydration, electrolyte disturbances, weight loss, and metabolic decompensation.

This statement refers to which of the 4 cores of pathology?

a)

Etiology

b)

Pathogenesis

c)

Morphologic Changes

d)

Functional Changes

e)

Clinical Manifestation

10.

Chronic obesity leads to increased insulin resistance due to raised levels of free fatty acids (FFAs) from uncontrolled lipolysis. This can contribute to the onset of symptomatic diabetes.

This statement refers to which of the 4 cores of pathology?

a)

Etiology

b)

Pathogenesis

c)

Morphologic Changes

d)

Functional Changes

e)

Clinical Manifestation

11.

At the onset of overt hyperglycemia, a mixture of pseudoatrophic islets with cells producing glycogen, somatostatin and pancreatic poly-peptide, normal

islets, and islets containing both beta-cells and infiltrating

lymphocytes and monocytes may be seen.

This statement refers to which of the 4 cores of pathology?

a)

Etiology

b)

Pathogenesis

c)

Morphologic Changes

d)

Functional Changes

e)

Clinical Manifestation

12.

Type 1 diabetes mellitus is associated with selective destruction of insulin producing pancreatic β-cells. Once more than 90% of the β-cells are destroyed, overt hyperglycemia start to manifest.

This statement refers to which of the 4 cores of pathology?

a)

Etiology

b)

Pathogenesis

c)

Morphologic Changes

d)

Functional Changes

e)

Clinical Manifestation

13.

Nutrient composition has also been found to be a risk factor for developing type 2 DM, where increased fat and decreased carbohydrate consumption have contributed to hyperinsulinemia of obesity.

This statement refers to which of the 4 cores of pathology?

a)

Etiology

b)

Pathogenesis

c)

Morphologic Changes

d)

Functional Changes

e)

Clinical Manifestation

14.

In type 2 DM, the number and volume of beta cells are usually decreased to half the normal, and the alpha cell mass is increased. The islets exhibit hyalinization and amyloid deposition, containing islet amyloid polypeptide.

This statement refers to which of the 4 cores of pathology?

a)

Etiology

b)

Pathogenesis

c)

Morphologic Changes

d)

Functional Changes

e)

Clinical Manifestation

15.

Initially, the glucagon secreting cells within the pancreatic islets remain relatively preserved, resulting in excessive secretion of glucagon relative to insulin after protein meals.

This statement refers to which of the 4 cores of pathology?

a)

Etiology

b)

Pathogenesis

c)

Morphologic Changes

d)

Functional Changes

e)

Clinical Manifestation