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BLOOD BANKING

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

A cause for permanent deferral of blood donation is:

a)

diabetes

b)

residence in an endemic malaria region

c)

history of jaundice of uncertain cause

d)

history of therapeutic rabies vaccine

2.

Which one of the following constitutes permanent rejection status of a donor?

a)

A tattoo 5 months previously

b)

recent close contact with a patient with viral hepatitis

c)

2 units of blood transfused 4 months previously

d)

confirmed positive test for HBsAg 10 years previously

3.

According to AABB standards, which of the following donors may be accepted as a blood donor?

a)

traveled to an area endemic for malaria 9 months previously

b)

spontaneous abortion at 2 months of pregnancy, 3 months previously

c)

resides with a known hepatitis patient

d)

received a blood transfusion 22 weeks previously

4.

Which of the following blood components contains the most factor VIII concentration relative to volume?

a)

single-donor plasma

b)

platelets

c)

fresh whole blood

d)

cryoprecipitated AHF

5.

A blood donor has the genotype: hh, AB. What is his red blood cell phenotype?

a)

A

b)

B

c)

O

d)

AB

6.

A individual has been sensitized to the k antigen and has produced anti-k. What is her most probable Kell system genotype?

a)

KK

b)

Kk

c)

kk

d)

KoKo 

7.

Given the following typing results, what id this donor's racial ethnicity?

Le(a-b-); Fy(a-b-); Js(a+b+)

a)

African America

b)

Asian America

c)

Native America

d)

Caucasian

8.

In an emergency situation, Rh-negative red cells are transfused into an Rh-positive person of the genotype CDe/CDe. The first antibody most likely to develop is:

a)

anti-d

b)

anti-c

c)

anti-e

d)

andti-E

9.

Which of the following antigens is most likely to be involved in hemolytic disease of the newborn?

a)

Le(a)

b)

P(1)

c)

M

d)

Kell

10.

Which of the following would be the best source of Platelets for transfusion in the case of alloimmune neonatal thrombocytopenia?

a)

father

b)

Mother

c)

pooled platelet-rich plasma

d)

polycythemic donor

11.

To prevent graft-vs-host disease, RBCs prepared for infants who have received intra uterine transfusion should be:

a)

saline-washed

b)

irradiated

c)

frozen and deglycerolized

d)

group- and Rh- compatible with the mother

12.

Criteria determining Rh immune eligibility include:

a)

mother is Rh-positive

b)

infant is Rh-negative

c)

mother has not been previously immunized to the D antigen

d)

infant has a positive direct antiglobulin test

13.

The enzyme responsible for conferring H activity on the red cell membrane is alpha-:

a)

galactosyl transferase

b)

N-acetylgalactosaminyl transferase

c)

L-fucosyl transferase

d)

N-acetylglucosamynil transferase

14.

Although ABO compatibility is preferred, ABO incompatible product may be administered when transfusing:

a)

Cryoprecipitated AHF

b)

Single-donor plasma

c)

Fresh frozen plasma

d)

Granulocytes

15.

Which one of the following is an indicator of polyagglutination?

a)

RBCs typing as weak D+

b)

presence of red cell autoantibody

c)

decreased serum bilirubin

d)

agglutination with normal adult ABO compatible sera

16.

What happens to an antibody in neutralization study when a soluble antigen is added to the test

a)

Inhibition

b)

Dilution

c)

Complement fixation

d)

hemolysis

17.

Coughing, cyanosis, and difficult breathing are symptoms of which of the following transfusion reactions?

a)

febrile

b)

allergic

c)

circulatory overload

d)

hemolytic

18.

To prevent febrile transfusion reactions, which red Blood Cell product should be transfused?

a)

red blood cells, irradiated

b)

CMV-negative red blood cells

c)

red blood cells, leukocyte reduced

d)

IgA-deficient donor blood

19.

Leukocyte-poor red blood cells would most likely be indicated for patients with a history of:

a)

febrile transfusion reactions

b)

iron deficiency anemia

c)

hemophilia A

d)

von Villebrand disease

20.

A trauma patient who just received ten units of blood may develop:

a)

anemia

b)

polycythemia

c)

leukocytosis

d)

thrombocytopenia