Pediatric meningitis by:

Pediatric skin infections by:

Pediatric Bacterial rhinosinusitis and Otitis Media by:

Adults SS in ♀ sexually active and ♂ with benign prostatic hyperplasia cause:

Adults SS cause pneumonia in:

Adults, Diverticulosis ➡ Peritoneum ➡ Peritonitis ➡ Intra-abdominal abscess ➡ Bloodstream by

Special concerns by:

• ↑ susceptibility

• ↓ physiologic tolerance to infection

• ↑ likelihood underlying diseases

• Survival impact (adverse)

• ↑ atypical presentations• Hypothermia • Nonspecific presentations

Most common cause of UTIs and Prostatis in adults:

Most common cause of pneumonia in chronic alcoholics:

Gram - that Infects burn wounds and cause pneumonia in patients with cystic fibrosis. Also has the highest mortality rate in sepsis.

Most common cause of anaerobic sepsis in peritonitis.

Gram + the most common cause of pneumonia and meningitis in adults.

↑ pneumonia cases / intravascular devices caused by:

Petechiae / purpura is caused by:

Generalized erythroderma is caused by:

Ecthyma gangrenosum caused by:

Acute renal failure, DIC and ARDS are complications of:

CNS dysfunction, Liver failure, Acute renal failure, DIC and ARDS are complications of:

Intestinal bleeding and Heart failure are complications of:

2 or more of the signs and symptoms:

At least 2 symptoms of SIRS + documented site of infection (labs isolation of microorganism) + Hypoperfusion + Hypotension

Sepsis with organ dysfunction + Hypoperfusion (lactic acidosis, oliguria, altered mental status) + Hypotension MAP <70 mmHg + IV fluids ⬆ BP

Sepsis induced Hypotension despite IV fluids + Hypoperfusion (lactic acidosis, oliguria, altered mental status)

Altered organ functions. Cannot be normalized.

Pneumonia by: S. pneumoniae, H. influenzae, Legionella, Chlamydia pneumoniae

Peritonitis: E. coli and bacteriodes fragilis

Skin and soft tissue infections by S. aereus and aerobic gram -

UTI by: Aerobic gram - bacilli and Enterococcus sp

Extracellular bacterias and fungi is mediated by:

Intracellular pathogens are mediated by:

Extracellular parasites are mediated by:

Clear pathogens during host defense rxns and in inducing tissue inflammation in autoimmune diseases.

LPS, TSS toxin and SpeA cause:

fever and endothelial cell damage occurs in:

Ceftriaxone, Cefepime and Gentamicin in:

Cefepime, Imipenem-cilastatin and Aminoglycosides in:

Imipenem-cilastatin and Aminoglycosides in:

Vancomycin and Imipenem-cilastatin or Piperacillin-tazobatactam in:

Vancomycin and cefepime in:

UTI infections:

Vancomycin + Ceftriaxone + Meropenem