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WorksheetsExam - 3 - Membrane and action potentials and refractory preiod
Total questions: 25
Worksheet time: 13mins
What of the following is closest to resting membrane potential?
+60 mV
-60 mV
-70 mV
-90 mV
What is the main factor for the negative resting membrane potential (-70mV)?
Potassium leak channels
Sodium leak channels
Calcium gated channels
Voltage gated potassium channels
What would the membrane potential be if the extracellular potassium levels increase to 7 mM potassium? (Note: ICF potassium is 150 mM and answer in whole numbers)
-81 mV
-70 mV
-65 mV
+ 60 mV
What membrane protein is responsible for maintaining the gradient?
K+ leak cannels
Na+ leak channels
Na+ voltage gated channels
Na+/K+ ATPase
Which membrane protein is primary responsible for the depolarization?
ligand gated Na+ channels
Na+/K+ ATPase
K+ leak channels
Voltage gated K+ channels
What membrane protein is responsible for the repolarization after depolarizing event?
K+ voltage gated channels
K+ leak channels
Na+ voltage gated channels
Chloride Channels
What number represents the resting membrane potential?
1
2
5
4
What number represents depolarization?
1
2
5
3
Which number represents the repolarization of membrane potential?
2
3
4
5
What number represents hyperpolarization?
1
3
4
5
What channel is responsible for the change at 2?
Na+ ligand gated ion channels
K+ gated ion channels
K+ leak channels
Na+ leak channels
At point 2 we would expect the M gate to be _______ and the H gate to be _____ on Sodium ligand-gated channels?
Open, closed
Closed, closed
Open, Open
Closed, open
Which number would we expect to see the H-gate to close in sodium channels?
1
2
3
5
The n-gate on potassium channels have what following characteristics?
Slow activation
quick activation
slow inactivation
quick inactivation
The m-gate and h-gate on sodium channels allow ligand gated sodium channels to have what characteristics?
Slow activation
slow deactivation
fast activation
fast deactivation
What kind of local potential is this?
excitatory
inhibitory
What kind of local potential is this?
excitatory
inhibitory
Which of the following would lead to decreased number of action potentials?
Inhibition of Na gated channels
Addition of Na channel
Increase in calcium channels
Activation of K leak channels
What refractory period happens when no stimulus regardless of strength can lead to a new action potential?
Absolute
Relative
What refractory period can lead to an action potential when applying a stronger stimulus?
absolute
relative
What is the main factor in the refractory period?
Na+ channels
Calcium channels
Potassium leak channels
Potassium voltage gated channels
What disease is associated with propagation due to decreased conduction velocity?
Multiple Sclerosis
Edema
myocardial infarction
Lambert-Eatons
What part of the nerve allows for faster propagation of the signal?
Myelin
dendrites
axons
terminal buttons
Which axon diameter leads to the fastest propagation (highest veolcity)?
large
small
diameter doesn't impact velocity
When a action potential moves down an axon it can be described as?
propagation
depolarization
reaching threshold
activation of a nerotransmitter
