WorksheetsTopic 4: Proteins and Enzymes
Total questions: 16
Worksheet time: 3mins
Amino acids can be classified based on what properties?
if they are non-polar, aliphatic
Aromatic
Essential or non-essential
All of the above
Essential amino acids are........
Amino acids that an organism is not able to synthesise
Amino acids that an organism can synthesise
Amino acids produced from other amino acids
Amino acids have a carboxyl and amino group, the amino has a basic pKa,
TRUE
FALSE
Peptides are.....
Small chains of amino acids
Larger than 10kDa
non essential and serve no biological purpose
The functional structure of a protein is called what?
Edman shape
Beta sheet
native fold
MALDI
Which kind of helix is the alpha-helix?
Left handed
Right handed
Beta sheet like arrangements are held together by which bond between backbone amides?
Van der Waals
Ionic
Hydrogen
Metallic
Proteins can be denatured by which of the following?
pH
heat or cold
Organic solvents
All of the above
Hsp70 and Hsp90 are examples of what?
Prions
Aggregates
Protein chaperones
Fibrous proteins
Concerning Protein turnover and proteostasis, the half life of a protein depends on which factor?
3D structure
C-term composition
N-term composition
When a protein is ubiquitinated it is.......
Sent to the lysosomes
Sent to the proteosomes
Sent to the plasma membrane for export
Degraded by mitochondrial enzymes
Collagen fibrils are assembled by crosslinking of triple helices
TRUE
FALSE
Co-opoertativity observed when O2 binds hemoglobin can be described as.......
Binding of first O2 decreases affinity at remaining sites
Two hemoglobin proteins cooperate to bind O2
Binding of first O2 increases the affinity at remaining sites
Alterations in the alpha helix to bind O2
Enzymes _______ the activation free energy.
Increase
Lower
Do not change
Competitive inhibitors do not bind the active site.
TRUE
FALSE
What kind of enzyme catalyses the following reaction A + H2O = B + C
Transferase
Ligase
Oxidoreductase
Hydrolase
