Font size
WorksheetsUnit Dosage Forms- Tablets
Total questions: 10
Worksheet time: 10mins
Tablets are unit dosage forms containing multiple doses of one or more API(s) prepared by compression or moulding.
This statement is accurate
Tablets are designed for single dosing
Tablets can be halved to give multiple doses
Tablets are not unit dosage forms
Buccal tablets dissolves in the mouth; API from sublingual tablets is absorbed from under the tongue; Dispirin and Zantac Effervescent dissolve in water which the patient can drink and vaginal and rectal tablets may be considered based on need.
What are the different types of unit dosage forms?
What are some routes of administration?
What are the different types of tablets?
What are route specific unit dosage forms?
In addition to the API(s), any of the following may be added to a tablet formulation. (Do not pluralize words, use British English).
(a)
The API and excipient mixture is converted into granules that flow well into dies, these are rendered compressible into mechanically strong and acceptable tablets.
What is granulation?
What is wet granulation?
what is dry granulation?
What is compression granulation?
Compression is the overarching manufacturing method used in the wet granulation, direct compression and film compression method of tablet manufacturing.
True
False
This process is not suitable for compounds and excipients that are sensitive to moisture or heat and the dissolution rate of tablets produced by this method may decrease with aging
dry/dry granulation
die filling granulation
direct compression
wet granulation
The following are forms of defect related to inert ingredients binding, cracking, picking, and sticking
True
False
Hardness variation is caused by unequal distribution of granule size, flow, drying method.
what is excipient related defect?
What is manufacturing related defect?
What is instrumentation related defect?
The tablet should maintain physical chemical and microbial stability throughout its shelf life
This is quality assurance standard
This is required for patient marketing
This is a requirement for testing
This is a quality attribute
What is the relationship between bioavailability and dissolution/disintegration?
increase disintegration increase surface area and bioavailability
increase dissolution increase motility and increase bioavailability
decrease dissolution increase surface area and increase bioavailability
increase disintegration reduce bioavailability
