Worksheetshistology (cell connections and cell junctions)
Total questions: 11
Worksheet time: 7mins
major families of cell adhesion molecules
selectins
cadherin superfamily
immunoglobulin superfamily
integrins
- intracellular adhesion molecule
- intercellular adhesion molecule
- vascular cell adhesion
- platelet endothelial cell adhesion
- mucosal addressin cell adhesion
integrins
immunoglobulin superfamily
selectins
cadherin superfamily
correct about selectins
form desmosomes and adherens junctions
consisting of more than 25 molecules
an epidermal growth factor-like region
bind epithelial and muscle cells to laminin in the basal lamina
correct about integrins
allow platelets to stick to exposed collagen in a damaged blood vessel
consists of more than 25 molecules
membrane-spanning region and a short cytoplasmic region
primarily link epithelial and muscle cells to their neighbours
bind muscle cells and epithelial to laminin in the basal lamina
true about this junction
provide metabolic and electrical continuity via the pores of the cells
found in the epithelial lining of digestive tract
blocking the movement of bacteria and small molecules from the lumen of the gut
located beneath the membranes of adjacent cells
allow passage of ions and small molecules
function of tight junction
allow passage of ions and small molecules
form an impermeable barrier
particularly important in cardiac muscle
secondary function of blocking the movement of bacteria and small molecules from the lumen of the gut
what is the types of adherent junctions
spot desmosome
belt desmosome
apical desmosome
bottom desmosome
hemidesmosome
which is the correct pair
tight junction- seals neighbouring cells together in an epithelial sheet to prevent leakage of molecules between them
desmosome-allows the passage of small water-soluble ions and molecules
hemidesmosome - anchors intermediate filaments in a cell to the basal lamina
gap junction - anchors intermediate filaments in a cell to the basal lamina
adherens junction - joins an actin bundle in one cell to a similar bundle in a neighboring cell
- provides both an anchor and a fluid conduit
- provides metabolic and electrical continuity via the pores between cells
hemidesmosome
tight junction
gap junctions
adherens junction
seals neighbouring cells together in a epithelial sheet to prevent leakage of molecules between them
gap junction
adherens junction
tight junction
hemidesmosome
desmosome
desmosome
seals neighbouring cells together in an epithelial sheet to prevent leakage of molecules between them
anchors intermediate filaments in a cell to the basal lamina
joins an actin bundle in one cell to a similar bundle in a neighbouring cell
joins the intermediate filaments in one cell to those in a neighbour
allow the passage of small water-soluble ions and molecules
