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Chapter 9 Radbio

Total questions: 59

Worksheet time: 30mins

Name
Class
Date
1.

Line 1 on the response curves represents

a)

linear non-threshold curve

b)

linear threshold curve

c)

nonlinear threshold curve

d)

sigmoid threshold curve

2.

 

Line 2 on the response curves represents;

a)

non-linear threshold curve

b)

linear threshold curve

c)

linear non- threshold curve

d)

sigmoid threshold curve

3.

 

Line 3 on the response curves represents

a)

nonlinear threshold curve

b)

linear threshold curve

c)

linear non-threshold curve

d)

sigmoid threshold curve

4.

After the Chernobyl disaster in 1986, an attempt was made to prevent thyroid cancer in Poland and some other countries, resulting from the accidental overdose of iodine-131. _______________ was administered to children as a substitute to block the gland’s uptake of iodine-131.

a)

Sodium chloride

b)

Potassium bromide

c)

Sodium bicarbonate

d)

Potassium iodide

5.

Among the atomic bomb survivors, the number of leukemia victims has _______________ since the late 1940s and early 1950s. However, the occurrence rates of other radiation-induced malignancies have continued to ___________since the late 1950s and early 1960s.

a)

slowly declined; escalate

b)

increased rapidly; decrease

c)

increased slowly; decrease

d)

rapidly declined; decrease

6.

Currently, evidence of radiation-induced hereditary effects has not been observed in persons employed in diagnostic imaging or in persons undergoing radiologic examinations. Even with this information, it is still recommended that

1. gonadal shielding be effectively used.

2. all radiation exposure be maintained as low as reasonably achievable (ALARA).

3. alternative procedures be substituted for x-ray procedures whenever diagnostic information must be obtained.

a)

1 and 3

b)

2 only

c)

1,2 and 3

d)

1 and 2

7.

During the 1950s and 1960s, the Navajo people of Arizona and New Mexico who mined uranium for fuel for nuclear weapons and power plants developed lung cancer years after their exposure. This provides an example of which of the following?

a)

Late stochastic effects

b)

Early tissue reactions

c)

Late tissue reactions

d)

Late genetic effects

8.

Genetic effects from exposure to ionizing radiation occur as a result of radiation-induced damage to the DNA molecule in which of the following?

1. Sperm of a man

2. Ova of a woman

3. Somatic cells of men and women

a)

2 and 3

b)

1 and 3

c)

1 and 2

d)

3 only

9.

In which of the following human populations is the risk for causing a radiation-induced cancer not directly measurable?

1. All patients in diagnostic radiology subjected to a radiation dose below 0.1 Sv

2. Chernobyl radiation accident victims living in contaminated villages

3. Atomic bomb survivors

a)

1 only

b)

2 only

c)

3 only

d)

1 and 2

10.

The term linear nonthreshold relationship implies that the biologic response to ionizing radiation is

a)

directly proportional to the dose all the way down to levels approaching zero.

b)

inversely proportional to the dose all the way down to levels approaching zero.

c)

directly proportional to the square of the dose all the way down to levels approaching zero.

d)

inversely proportional to the square of the dose all the way down to levels approaching zero.

11.

To assess the magnitude and severity of late effects on the exposed population from the 1986 nuclear power station accident at Chernobyl

a)

short-term follow-up studies are necessary.

b)

minimal follow-up is only necessary because the exposed population did not receive sufficient radiation exposure to cause severe late effects.

c)

follow-up is not necessary because the radiation received by the entire exposed population was fatal.

d)

long-term follow-up studies are necessary.

12.

What do agents such as specific chemicals, viruses, and ionizing radiation have in common?

a)

Nothing

b)

They can increase the frequency of mutations in only those members of the population who are already genetically impaired.

c)

They are all mutagens that may increase the frequency of mutations.

d)

They always cause spontaneous abortions during the first trimester of pregnancy.

13.

What is the mean value of the radiation doubling equivalent dose for humans, as determined from studies of the children of the atomic bomb survivors of Hiroshima and Nagasaki?

a)

5.67 Sv

b)

1.00 Sv

c)

1.56 Sv

d)

3.00 Sv

14.

When a prediction is made that the number of excess cancers rises as the natural incidence of cancer increases with advancing age in the population, the risk is considered to be

a)

relative.

b)

absolute.

c)

excess.

d)

quadratic.

15.

Which of the following are sources of low-level radiation exposure?

a)

1. X-rays and radioactive materials used for diagnostic purposes.

b)

2. Employment-related exposure in medicine and industry.

c)

3. Natural background radiation

d)

4. Proton released from coal mine

16.

Which of the following late effects caused by exposure to ionizing radiation is considered to be most important?

a)

Cancer

b)

Cataract formation

c)

Embryologic or birth defects

d)

None; all are considered to be of equal importance.

17.

Studies showed that postpartum patients treated with ionizing radiation for relief of mastitis are a group of individuals in whom the results of radiation exposure to healthy breast tissue via scattered radiation indicate that radiation

a)

cannot cause breast cancer.

b)

can cause breast cancer.

c)

can cause breast enlargement.

d)

can cause breast shrinkage.

18.

Some mutations in genetic material occur spontaneously, without a known cause. In humans, a hereditary disorder is present in approximately _________ of all live births in the United States.

a)

10%

b)

15%

c)

25%

d)

5%

19.

Radiation-induced cataracts in humans follow a ______ dose–response relationship.

a)

nonthreshold, nonlinear

b)

nonthreshold, linear

c)

threshold, linear

d)

threshold, nonlinear

20.

Mutations in genes and DNA that occur at random as natural phenomena are called

a)

spontaneous mutations.

b)

carcinogenic mutations.

c)

sporadic mutations.

d)

stochastic mutations.

21.

Radium decays with a half-life of

a)

8 days.

b)

50 years.

c)

1500 years.

d)

1622 years.

22.

Which of the following measures the effectiveness of ionizing radiation in causing mutations?

a)

Doubling dose

b)

Dose–response curve

c)

RBE

d)

LD 50/30

23.

The linear dose–response model is used to establish radiation protection standards because it accurately reflects the effects of:

a)

 Both high-LET and low-LET types of radiation at lower doses

b)

 Low-LET radiation at lower doses

c)

 High-LET radiation at higher doses

d)

Both high-LET and low-LET types of radiation at higher doses

24.

Radiation can induce genetic damage by which of the following means

a)

Interacting with somatic cells of only one parent

b)

Interacting with somatic cells of both parents

c)

Altering the essential base coding sequence of DNA

d)

Interacting with somatic cells of both parents

25.

During the preimplantation stage of development, the fertilized ovum divides and forms undifferentiated cells. If this structure is irradiated with a dose in the range of 0.05 to 0.15 Gyt which of the following will result?

a)

Delayed bone growth

b)

Congenital abnormalities

c)

Embryonic death 

d)

Microcephaly

26.

If a person receives radiation exposure sufficient to cause the gastrointestinal syndrome, fatality occurs primarily because of

a)

catastrophic damage to the epithelial cells that line the gastrointestinal track, resulting in the death of the exposed person within 3 to 5 days from a combination of infection, fluid loss, and electrolytic imbalance.

b)

convulsive seizures.

c)

edema in the cranial vault.

d)

meningitis.

27.

For persons with hematopoietic syndrome, survival time shortens as the radiation dose

a)

decreases.

b)

increases.

28.

Which of the following is not a form of acute radiation syndrome?

a)

Cerebrovascular syndrome

b)

Gastrointestinal syndrome

c)

Carcinogenic syndrome

d)

Hematopoietic syndrome

29.

The term LD 50/30 signifies the whole-body dose of radiation that can be lethal to

a)

30% of the exposed population in 30 days.

b)

50% of the exposed population in 50 days.

c)

50% of the exposed population in 30 days.

d)

30% of the exposed population in 50 days.

30.

Atrophy refers to

a)

aging of the skin from radiation exposure.

b)

shrinkage of organs and tissues after a high radiation dose is received.

c)

necrosis of the hypodermis from radiation exposure.

d)

wrinkling of the skin from radiation exposure.

31.

The correct order of development for the female germ cell from the stem cell phase to the mature cell is

a)

primordial follicle, ovum, corpus luteum, mature follicle.

b)

primordial follicle, mature follicle, corpus luteum, ovum.

c)

ovum, mature follicle, corpus luteum, primordial follicle.

d)

corpus luteum, primordial follicle, mature follicle, ovum.

32.

The prodromal stage of acute radiation syndrome is actually the

a)

recovery period.

b)

manifest illness period.

c)

initial stage.

d)

latent period.

33.

A single absorbed dose of 2 Gyt can cause a radiation-induced skin erythema within

a)

24 to 48 hours after irradiation.

b)

12 hours after irradiation.

c)

1 hour after irradiation.

d)

6 hours after irradiation.

34.

Grenz rays were once used to treat and successfully cure

a)

skin diseases such as ringworm.

b)

lupus disease.

c)

acute radiation syndrome.

d)

cancer.

35.

During cardiovascular or other therapeutic interventional procedures that use high-level fluoroscopy for extended periods, the effects of ionizing radiation on the skin are

a)

significant.

b)

moderate.

c)

nonexistent.

d)

minimal.

36.

After the reception of a high radiation dose, significant cell death usually results, leading to the shrinkage of organs and tissues. This process is referred to as:

a)

 Atrophy

b)

Desquamation

c)

Erythema

d)

Radiodermatitis

37.

Approximately what percentage of the human body’s surface skin cells is replaced daily by stem cells from an underlying basal layer?

a)

2%

b)

12%

c)

35%

d)

 50%

38.

How many mature ova are produced, matured, and made available for fertilization during a woman’s reproductive life cycle?

a)

50 to 100

b)

 100 to 200

c)

 300 to 400

d)

400 to 500

39.

Many early radiologists and dentists developed a significant reddening of the skin caused by exposure to ionizing radiation. This condition is called:

a)

Dermabrerration

b)

 Desquamation

c)

Epidermatitis

d)

Radiodermatitis

40.

In humans with the gastrointestinal form of ARS, the part of the body most severely affected is the:

a)

Brain

b)

Heart

c)

Large intestine

d)

Small intestine

41.

The use of high-dose-rate fluoroscopy for extended periods can result in:

a)

A significant reduction in radiation-induced skin injuries for patients

b)

Minimal total-body radiation exposure for patients

c)

Radiation-induced skin injuries for patients

d)

The need for all patients to have periodic blood counts to monitor radiation dose received

42.

The term LD 50/30 signifies the whole-body dose of radiation that can be lethal to

a)

30% of the exposed population in 50 days.

b)

50% of the exposed population in 30 days.

c)

50% of the exposed population in 50 days.

d)

30% of the exposed population in 30 days.

43.

The correct order of development for the female germ cell from the stem cell phase to the mature cell is

a)

ovum, mature follicle, corpus luteum, primordial follicle.

b)

corpus luteum, primordial follicle, mature follicle, ovum.

c)

primordial follicle, ovum, corpus luteum, mature follicle.

d)

primordial follicle, mature follicle, corpus luteum, ovum.

44.

Research has shown that repeated radiation injuries have a

a)

sigmoidal effect.

b)

quadratic effect.

c)

cumulative effect.

d)

threshold effect.

45.

A single absorbed dose of 2 Gyt can cause a radiation-induced skin erythema within

a)

12-18 hours after irradiation.

b)

1 hour after irradiation.

c)

6 hours after irradiation.

d)

24-48 hours after irradiation.

46.

If a person receives radiation exposure sufficient to cause the gastrointestinal syndrome, fatality occurs primarily as a result of

a)

catastrophic damage to the epithelial cells that line the gastrointestinal track.

b)

convulsive seizures.

c)

edema in the cranial vault.

d)

meningitis.

47.

Some local tissues suffer immediate consequences from high radiation doses. Examples of such tissues include

a)

bone marrow.

b)

male and female reproductive organs.

c)

skin.

48.

What determines the rate of production of chromosome aberrations

a)

The total radiation dose given to a somatic cell

b)

The total radiation given to a genetic cell

c)

The period of time in which radiation dose was delivered

d)

The total radiation set to be delivered

49.

In female oogonia, the ovarian stem cells

a)

multiply to millions of cells only during fetal development

b)

divide and reduce in number only during fetal development.

c)

are not present during fetal life.

d)

are present only in very small numbers during fetal life.

50.

Which of the following are classified as early tissue reactions of ionizing radiation?

a)

Nausea, epilation, and intestinal disorders

b)

Erythema, cataract formation, and cancer

c)

Male and female sterility, embryologic defects, and cancer

d)

Blood disorders, fever, and genetic effects

51.

The hematopoietic form of acute radiation syndrome is also called the

a)

bone marrow syndrome.

b)

Auger syndrome.

c)

cerebrovascular syndrome.

d)

cytogenetic syndrome.

52.

Organ and tissue response to radiation exposure depends on factors such as

a)

radiosensitivity

b)

reproductive characteristics

c)

growth rate.

d)

time recieved

53.

A term that is synonymous with loss of hair is

a)

desquamation.

b)

atrophy.

c)

epilation.

d)

radiodermatitis.

54.

The correct order of development of the male

a)

spermatogonia, spermatocyte, spermatid, sperm.

b)

spermatocyte, spermatogonia, spermatid, sperm.

c)

spermatid, spermatogonia, spermatocyte, sperm.

d)

sperm, spermatid, spermatogonia, spermatocyte.

55.

Chromosomal damage can be caused by

a)

high radiation doses only.

b)

low radiation doses only.

c)

both low and high radiation doses.

d)

none of the options.

56.

Moist and dry desquamation can be caused by

a)

high radiation doses.

b)

low radiation doses.

c)

radiation doses received during routine diagnostic imaging procedures.

d)

radiation dose received during annual testing of diagnostic imaging equipment.

57.

Early tissue reactions are

a)

not common in diagnostic imaging.

b)

common in diagnostic imaging.

c)

a result of irradiation of acellular tissue.

d)

a result of Grenz rays in a diagnostic x-ray beam.

58.

QuestionData from epidemiologic studies of human populations exposed to doses of ionizing radiation sufficient to cause acute radiation syndrome have been obtained from

a)

atomic bomb survivors of Hiroshima and Nagasaki.

b)

Marshall Islanders who were inadvertently subjected to high levels of fallout during an atomic bomb test in 1954.

c)

nuclear radiation accident victims, such as those injured in the 1986 Chernobyl disaster.

d)

patients who have undergone radiation therapy.

59.

During the major response stages of acute radiation syndrome after the prodromal stage and a period of false calm that may last for several days, the stage when symptoms that affect the hematopoietic, gastrointestinal, and cerebrovascular systems occurs, this stage is called

a)

the latent period.

b)

manifest illness.

c)

the cytogenic syndrome.

d)

recovery.