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2EMT - Lipid Metabolism

Total questions: 20

Worksheet time: 11mins

Name
Class
Date
1.

Identify this molecule

a)

Glycerol

b)

Glycerol 1-phosphate

c)

Fatty acid

d)

acetoacetateglycglglycerol

2.

Identify this molecule

a)

Glycerol

b)

Glycerol 1-phosphate

c)

Fatty acid

d)

acetoacetateglycglglycerol

3.

Identify this molecule

a)

Glycerol

b)

Glycerol 1-phosphate

c)

Fatty acid

d)

acetoacetateglycglglycerol

4.

A health disorder that builds up certain amount of fatty acids in spleen and liver.

a)

Gaucher disease

b)

Tay-Sachs disease

c)

hyperlipidemia

d)

hypercholesterolemia

5.

A rare genetic disorder that is caused by the absence of an enzyme breaking down fatty acids.

a)

Gaucher disease

b)

Tay-Sachs disease

c)

hyperlipidemia

d)

hypercholesterolemia

6.

A health condition with high level of lipids in the blood.

a)

Gaucher disease

b)

Tay-Sachs disease

c)

hyperlipidemia

d)

Zellweger Syndrome

7.

A disease caused by defects in the 13 genes, and is one of four related diseases known as peroxisome biogenesis disorders.

a)

Gaucher disease

b)

Tay-Sachs disease

c)

hyperlipidemia

d)

Zellweger Syndrome

8.

A rare inherited condition caused by fatty acid enzyme malfunction.

a)

Gaucher disease

b)

Tay-Sachs disease

c)

Fatty Acid Oxidation Disorder

d)

Zellweger Syndrome

9.

In beta oxidation of FA, supply the enzyme that catalyzed the reaction: Fatty acyl-CoA -> Trans-delta2-Enoyl-CoA

a)

Acyl-CoA dehydrogenase

b)

Enoyl-CoA hydratase

c)

hydroxyacyl-CoA dehydrogenase

d)

Thiolase

10.

In beta oxidation of FA, supply the enzyme that catalyzed the reaction: Trans-delta2-Enoyl-CoA -> L-beta-hydroxyacyl-CoA

a)

Acyl-CoA dehydrogenase

b)

Enoyl-CoA hydratase

c)

hydroxyacyl-CoA dehydrogenase

d)

Thiolase

11.

In beta oxidation of FA, supply the enzyme that catalyzed the reaction: L-beta-hydroxyacyl-CoA -> beta-ketoacyl-CoA

a)

Acyl-CoA dehydrogenase

b)

Enoyl-CoA hydratase

c)

hydroxyacyl-CoA dehydrogenase

d)

Thiolase

12.

In beta oxidation of FA, supply the enzyme that catalyzed the reaction: beta-ketoacyl-CoA -> Fatty acyl-CoA

a)

Acyl-CoA dehydrogenase

b)

Enoyl-CoA hydratase

c)

hydroxyacyl-CoA dehydrogenase

d)

Thiolase

13.

In beta oxidation of FA, What is the type of reaction involved in Step 1?

a)

Oxidation

b)

Hydration

c)

Cleavage

d)

Isomerization

14.

In beta oxidation of FA, What is the type of reaction involved in Step 2?

a)

Oxidation

b)

Hydration

c)

Cleavage

d)

Isomerization

15.

In beta oxidation of FA, What is the type of reaction involved in Step 3?

a)

Oxidation

b)

Hydration

c)

Cleavage

d)

Isomerization

16.

In beta oxidation of FA, What is the type of reaction involved in Step 4?

a)

Oxidation

b)

Hydration

c)

Cleavage

d)

Isomerization

17.

In beta oxidation of FA, the extra step involved in unsaturated FA is isomerization of cis double bond to trans double bond.

a)

False

b)

True

18.

Short chain FA, are carried directly into the mitochondrial matrix while Long chain FA needs a carrier to be transported into the matrix.

a)

False

b)

True

19.

Synthesis starts with reaction of three molecules of acetyl CoA to form the six carbon compound HMG-CoA.

a)

False

b)

True

20.

2 molecules of ATP are lost in activation of saturated FA, stearic acid before beta oxidation.

a)

False

b)

True