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nucleic acids

Total questions: 48

Worksheet time: 37mins

Name
Class
Date
1.

A SWISS PHYSIOLOGIST -------- DISCOVERED NUCLEIC ACID IN THE YEAR 1869, WHILE STUDYING THE NUCLEI OF WHITE BLOOD CELLS

(a)  

2.

NUCLEIC ACIDS ARE FOUND THROUGHOUT A CELL

a)

TRUE

b)

FALSE

3.

A TYPE OF BIOMOLECULES THAT HAS THE PROPERTY OF REPLICATING ITSELF, THUS NATURE CHOOSE THIS MOLECULES TO SERVE AS THE REPOSITORY AND TRNSMITTER OF GENETIC INFORMATION IN EVERY CELL AND ORGANISM

a)

PROTEINS

b)

DNA

c)

LIPIDS

d)

NUCLEIC ACID

4.

----- IN AN ORGANISMS ARE EXACT REPLICAS

(a)  

5.

A MOLECULE THAT IS RESPONSIBLE FOR THE INFORMATION ON HOW TO MAKE NEW CELLS.

a)

LIPIDS

b)

DNA

c)

RNA

d)

NUCLEIC ACID

6.

WHAT ARE THE TWO TYPES OF NUCLEIC ACID

a)

RIBONUCLEIC ACID (RNA)

b)

DEOXYRIBONUCLEIC ACID (DNA)

c)

ALL OF THE ABOVE

d)

NONE OF THE ABOVE

7.

------ CAN BE FOUNF IN THE CELLS NUCLEUS

(a)  

8.

IT IS A STORAGE AND TRANSFER OF GENETIC INFORMATION AND IT PASS FROM ONE CELL TO ANOTHER DURING CELL DIVISION

a)

DEOXYRIBONUCLEIC ACID (DNA)

b)

RIBONUCLEIC ACID (rna)

c)

NUCLEIC ACID

d)

PROTEINS

9.

IT OCCURS IN ALL PARTS OF THE CELL AND ITS PRIMARY FUNCTION IS TO SYNTHESIZE THE PROTEINS

a)

RIBONUCLEIC ACID (RNA)

b)

DEOXYRIBONUCLEIC ACID (DNA)

c)

PROTEINS

d)

NUCLEIC ACID

10.

----- IS A SEGMENT OF DNA WHICH SPECIFIES THE CHAIN OF AMINO ACIDS THAT COMPRISES THE PROTEIN MOLECULE

(a)  

11.

ALL OF THE GENETIC MATERIAL (THE TOTAL DNA) CONTAINED IN THE CHROMOSOMES OF AN ORGANISM

(a)  

12.

IS TRANSCRIBED BY mRNA AND TRANSLATED BY tRNA AND rRNA INTO THOUSANDS OF DIFFERENT PROTEINS

a)

GENETIC MESSAGE

b)

GENE

c)

GENOME

d)

GENETIC

13.

is a theory stating that genetic information flows only in one direction, from DNA, to RNA, to protein, or RNA directly to protein.

(a)  

14.

NUCLEIC ACIDS IS A POLYMER IN WHICH THE REPEATING UNIT IS (a)  

15.

WHAT ARE THE 3 COMPONENTS OF A NUCLEOTIDE?

a)

-PENTOSE SUGAR

-PHOSPHATE GROUP

-HETEROCYCLIC BASE

b)

DNA

RNA

NUCLEIC ACID

c)

PROTEINS

LIPIDS

AMINO ACID

d)

PENTOSE SUGAR

CHROMOSOMES

PHOSPHATE GROUP

16.

COMPONENTS OF DNA INCLUDES THE FOLLOWING, EXCEPT;

a)

THYMINE

b)

DEOXYRIBOSE

c)

URACIL

d)

GUANINE

17.

COMPONENTS OF RNA INCLUDES THE FOLLOWING, EXCEPT;

a)

URACIL

b)

RIBOSE

c)

PHOSPHATE

d)

THYMINE

18.

formed from condensation reaction between a five-carbon monosaccharide and a purine or pyrimidine base derivative.

(a)  

19.

for pyrimidine bases – suffix (a)   is used (cytidine, thymidine, uridine)

20.

for purine bases – suffix (a)   is used (adenosine, guanosine)

21.

prefix “ (a)   ” is used to indicate deoxyribose present (e.g: deoxythymidine)

22.

A GROUP THAT IS ADDED TO A NUCLEOSIDE

(a)  

23.

IN NUCLEOTIDE NOMENCLATURE IT IS adenylic acid or adenosine monophosphate (AMP)

a)

ADENOSINE

b)

GUANOSINE

c)

CYTIDINE

d)

URIDINE

24.

IN NUCLEOTIDE NOMENCLATURE IT IS cytidylic acid or cytidine monophosphate (CMP)

a)

CYTIDINE

b)

URIDINE

c)

DEOXYTHYMIDINE

d)

ADENOSINE

25.

are referred to as nucleic acid backbone ; found in all nucleic acids

(a)  

26.

Sugars are NOT different in DNA and RNA

a)

FALSE

b)

TRUE

27.

is a polynucleotide in which each of the monomers contains ribose , a phosphate group, and one of the heterocyclic bases adenine, cytosine, guanine , or uracil

(a)  

28.

is a nucleotide polymer in which each of the monomers contains deoxyribose, a phosphate group, and one of the heterocyclic bases adenine, cytosine , guanine, or thymine .

(a)  

29.

a high mol.wt., double -stranded polynucleotide that occurs almost exclusively in the nucleus of the cell • primary function is storage and transfer of genetic information which is used (indirectly) to control many functions of a living cell

(a)  

30.

the structure of the four bases permit hydrogen bonding between specific base pairs: Adenine always pairs with Thymine and Guanine with Cytosine

a)

TRUE

b)

FALSE

31.

the proof of this base -pairing came when Watson and Crick proved by x -ray diffraction that the DNA structure was a double helix whose chains were ____________ AND _________

(a)  

32.

means that A binds to T and C to G between the chains -the sequence of bases on one strand automatically determines the sequence of bases on the other strand

a)

COMPLEMENTARY

b)

ANTIPARALLEL

c)

PARALLEL

d)

COMPLEMENT

33.

means that each end of the helix contains the 5’ end of one strand and the 3’ end of the other, so that the chains travel in opposite directions -only when the 2 strands are antiparallel can the base pairs form the H -bonds that hold them together

a)

COMPLEMENTARY

b)

ANTIPARALLEL

c)

COMPLEMENT

d)

PARALLEL

34.

Predict the sequence of bases in the DNA strand complementary to the single DNA strand shown below:

5’ A–A–T–G–C–A–G–C–T 3’

(a)  

35.

The loss of helical structure due to disruption of H –bonds is called (a)   or melting , where the double strands separate into single strands.

36.

extend into the center at right angles to the acids of the helix as if they are the steps of the spiral staircase

(a)  

37.

the coding sequences; interrupted by noncoding sequences

a)

EXONS

b)

INTRONS

c)

PALINDROME

d)

CRUCIFORM

38.

the noncoding sequences; from 10 to 10,000 bases long

a)

EXONS

b)

INTRONS

c)

PALINDROME

d)

CRUCIFORM

39.

a DNA sequence that contains the same information whether it is read forward or backward; e . g . “MADAM, I’M ADAM”

a)

INTRONS

b)

EXON

c)

CRUCIFORM

d)

PALINDROME

40.

as their name implies, are crosslike structures • when a DNA sequence contains a palindrome

a)

INTRONS

b)

CRUCIFORM

c)

PALINDROME

d)

EXONS

41.

Process by which DNA molecules produce exact duplicates of themselves

(a)  

42.

First step is the separation of the strands – accomplished by (a)   , which breaks the H -bonds between base pairs

43.

positive supercoiling results when H -bonds are broken, this is relieved by

(a)  

44.

when supercoiling is relieved, (a)   binds to the separated strands to keep them apart

45.

catalyzes synthesis of a 10 -12 base piece of RNA to “prime” the DNA replication

(a)  

46.

“reads” the parental strand or template, catalyzing the polymerization of a complementary daughter strand; the enzyme checks the correct base pairing and catalyzes the formation of phosphodiester linkages

(a)  

47.

the 3’ strand is called the ________ because it is replicated in a continuous process in the direction of the unwinding;

a)

LEADING STRAND

b)

LAGGING STRAND

c)

FAST STRAND

d)

SLOW STRAND

48.

the 5’ strand is the ________, it is replicated in a discontinuous mechanism and grows in segments (Okazaki fragments) in the opposite direction; the segments are later connected by DNA ligase

a)

LAGGING STRAND

b)

LEADING STRAND

c)

SLOW STRAND

d)

FAST STRAND