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Protein Synthesis and Mutations Review

Total questions: 50

Worksheet time: 1hrs 13mins

Name
Class
Date
1.

Muscle cells differ from nerve cells mainly because they

a)

express different genes.

b)

contain different genes.

c)

use different genetic codes.

d)

have unique ribosomes

2.
What mutation has occurred here? 
T-G-A-C-C-A
T-G-A-G-C-A
a)
Substitution
b)
Deletion
c)
Insertion
d)
Frameshift 
3.
What amino acid is represented by the codon UUA?
a)
Phenylalanine
b)
Tyrosine
c)
Leucine
d)
Stop codon
4.
What process is going on in this photo? 
a)
Transcription 
b)
Translation 
c)
Replication 
d)
All the above 
5.

A mutation is a _______________ in the nucleotide base sequence of a gene.

a)

wrinkle

b)

change

c)

bump

d)

tumor

6.

I carry a copy of the Genetic info from the nucleus to the ribosome. Who Am I?

a)

mRNA

b)

tRNA

c)

rRNA

d)

DNA

7.
A triplet (3 bases)  of mRNA is called a
a)
codon
b)
anticodon
c)
amino acid
d)
peptide bond
8.
What is the correct sequence?
a)
RNA --> DNA --> Protein
b)
Protein --> RNA --> DNA
c)
DNA --> RNA --> Protein
d)
DNA --> Protein --> RNA
9.
_______ is made during transcription and ________ is made during translation.
a)
mRNA / a protein
b)
a protein / mRNA
c)
Ribosome / Nucleus
d)
mRNA / tRNA
10.

True or False: All of your body cells contain the same genes.

a)

True

b)

False

11.

Which form of RNA carries amino acids from the cytoplasm to the ribosome?

(a)  

12.

Which of the following images is a DELETION?

a)
b)
c)
13.

Which of the following images is a SUBSTITUTION?

a)
b)
c)
14.

Some mutations can be to the benefit of the species.

a)

FALSE

b)

TRUE

15.
Transcription is a process that in eukaryotic cells takes place in the:
a)
Nucleus
b)
Cytoplasm
c)
Golgi Apparatus
d)
Rough E.R.
16.

A mutation is a _______________ in the nucleotide base sequence of a gene.

a)

wrinkle

b)

change

c)

bump

d)

tumor

17.

Which of the following statements best describes why a change in only one DNA nucleotide base of a gene on the DNA strand could result in an incorrect protein being produced by the gene?

a)

The change prevents mRNA from being made.

b)

The change causes cells to divide in an uneven way.

c)

The change creates an additional mRNA strand.

d)

The change alters the amino acid sequence coded for by the

gene.

18.

Messenger RNA (mRNA) does what?

a)

transfers/brings amino acids

b)

carries the genetic code that was copied from DNA

c)

Builds the Ribosome

d)

Unzip DNA

19.

What mutation to the DNA triplet bellow WILL NOT EFFECT the protein made?

3' CCA 5'

a)

CAG

b)

CCC

c)

TCA

d)

CTT

20.

Would a mutation that occurred in you skin cells be passed on to your offspring?

a)

Yes because mutations in gametes are passed on

b)

No because mutations that occur in somatic cells are not passed on

c)

Yes because mutations always will be passed on

d)

No because mutations are never passed on

21.

The regulation of gene expression within each cell type is important because it ?

a)

allows each cell to do the exact same thing

b)

mutates genes so they can perform different functions

c)

enables cells to perform their specific functions

d)

allows the cells to rest

22.

Why are insertion and deletion (frameshift) mutations so harmful?

a)

They change all of the codons from the mutation on down the strand, which changes the entire amino acid sequence

b)

They insert things that an organism doesn't need.

c)

They often delete things that organisms need.

d)

Insertion and deletions are not any more harmful than substitution mutations.

23.
A type of substitution in which no  amino acids change is called 
a)
Missense
b)
Nonsense
c)
Silent
d)
Deletion
24.
Mutations affect the ________ of a protein. Because of this the proteins ______ is affected as well. 
a)
gene, function 
b)
sequence, gene
c)
shape,function
25.

What are the three types of gene mutation?

a)

Insertion, Deletion, Subsitution

b)

Aberration, Deletion, Substitution

c)

Inversion, Duplication, Insertion

d)

Insertion, Duplication, Substitution

26.
Choose the nucleotide sequence of the RNA strand that would be complementary to the following strand: 
GTAGTCA
a)
UATUAGA
b)
ACGACTG
c)
CAUCAGU
d)
CATCAGT
27.

DNA makes RNARNA makes proteins

Proteins make life.

a)

Homeostasis

b)

Mendelian Genetics

c)

Central Dogma

d)

Myocardial Infarction

28.
What is the correct amino acid sequence for the mRNA code AUGCCAGUAUGA
a)
Met-Pro-Ala-Val
b)
Met-Pro-Val
c)
Tyr-Gly-His
d)
Tyr-Gly-Arg-His
29.
Which process is happening in this picture?
a)
Transcription
b)
Translation
c)
Replication
30.
DNA has a _____________ structure. 
a)
double helix
b)
single strand
c)
ring 
d)
chain
31.

What is the role of mRNA in protein synthesis?

a)

it makes the bases that makes up DNA

b)

it copies a section of DNA and uses the information to create the appropriate protein

c)

it helps DNA perform replication

d)

it makes the amino acids used in protein synthesis

32.

In order for protein synthesis to occur, mRNA must leave the nucleus and travel to

a)

a ribosome in the cytoplasm

b)

a mitochondria in the cytoplasm

c)

a vacuole in the cytoplasm

d)

a chloroplast in the cytoplasm

33.

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC GTA CTT GAA T

What type of mutation has occurred?

a)

Chromosomal mutation

b)

Point mutation

c)

Frameshift mutation due to adding extra base

d)

Frameshift mutation due to deletion of base

34.

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC GAC TTG AAT

What type of mutation has occurred?

a)

Chromosomal mutation

b)

Point mutation

c)

Frameshift mutation

d)

No mutation occurred

35.

Original DNA = TAC GAC TTG AAT

Mutated DNA = TAC ACT TGA AT

What type of mutation has occurred?

a)

Chromosomal mutation

b)

Point mutation

c)

Frameshift mutation due to addition of base

d)

Frameshift mutation due to deletion of base

36.
DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.
a)
Substitution
b)
Deletion
c)
Insertion
d)
Inversion
37.
Are all mutations bad?
a)
Yes
b)
No
38.

Which type of mutation is MOST LIKELY to cause the greatest disruption?

a)

Frameshift

b)

Silent

c)

Point

39.
Which of the following does not cause mutations?
a)
X-rays
b)
Chemicals we smoke or eat
c)
Drinking water
d)
Tanning
40.
What is a Gene?
a)
A segment of RNA that encodes for a protein
b)
A chromosome
c)
A segment of DNA that encodes for a protein
d)
Your genome
41.

What is the order for Protein Synthesis?

a)

Transcription -> Translation -> Protein

b)

Translation - > Transcription -> Protein

c)

Protein -> Transcription -> Translation

d)

Translation -> Protein -> Transcription

42.
What amino acid is represented by the codon UUA?
a)
Phenylalanine
b)
Tyrosine
c)
Leucine
d)
Stop codon
43.

What is the correct amino acid sequence for the mRNA code AUG-CCA-GUA-UGA

a)

Met-Pro-Ala-Val

b)

Met-Pro-Val

c)

Tyr-Gly-His

d)

Tyr-Gly-Arg-His

44.

What codon is represented by the STOP amino acid?

a)

AUG

b)

UAA

c)

CUC

d)

GUA

45.
The codon CCU codes for what amino acid?
a)
Isoleucine
b)
Stop
c)
Methionine
d)
Proline
46.
Which amino acid pairs with the codon AGA
a)
Thr
b)
Arg
c)
Ala
d)
Glu
47.

How many codons code for phenylalanine?

a)

2

b)

3

c)

4

d)

1

48.

The following codon is translated into which amino acid?


AGG

a)

Methionine

b)

Isoleucine

c)

Histidine

d)

Arginine

49.

The following codon is translated into which amino acid?


UAA

a)

STOP

b)

Phenylalanine

c)

Valine

d)

Aspartic acid

50.

AAA-TTT is the DNA TRIPLET


WHAT AMINO ACIDS ARE MADE

a)

SERINE-LEUCINE

b)

LEUCINE-PHENYLALANINE

c)

PHENYLALANINE-LYSINE

d)

TYROSINE-LYSINE