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Immunotherapy

Total questions: 85

Worksheet time: 1hrs 25mins

Name
Class
Date
1.

Form of biotherapy that uses certain parts of the immune system to fight diseases.

(a)  

2.

      Collection of antibodies which can be isolated from donated blood provided by other individual.

(a)  

3.

Plays an important role in the first line of defense against viral infection.

(a)  

4.

   Added to many vaccines to increase immunogenicity and efficacy.

(a)  

5.

Derived from blood of animals or individuals who have been exposed to a given antigen.

(a)  

6.

An example of antisera that is derived from an animal presumably a horse which has been injected with snake venom.

(a)  

7.

Get antibodies from the spleen of the mouse and then add to the human cancerous myeloma cell.

(a)  

8.

Part mouse and part human

(a)  

9.

Fully human

(a)  

10.

10x much smaller than mabs and penetrate into tissues more easily. Much more effective and less time consuming.

(a)  

11.

Very widely used monoclonal antibody technique. Detecting the formation of an immunocomplex, the linkage of antibodies and antigens.

(a)  

12.

Used to identify parts of a cell in basic research and in diagnosing a test.

(a)  

13.

Uses laser detectors and computer technology to find the antigen associated in the cell.

(a)  

14.

Binding agent that is used to isolate specific molecules from solution.

(a)  

15.

Used to purify or to remove the antigen from the antibody.

(a)  

16.

Auto Greek word for self. Abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues.

(a)  

17.

Lupus, rheumatoid arthritis, systematic sclerosis

(a)  

18.

Multiple sclerosis and myasthenia gravis.

(a)  

19.

insulin dependent / juvenile diabetes

(a)  

20.

inflammatory bowel disease

(a)  

21.

The immune system is attacking the normal cells and destroys them.

(a)  

22.

Autoimmune diseases resulting from antibody stimulating receptors on certain cells.

(a)  

23.

An example of auto immune disease under neuromuscular. Latin and greek in origin, literally means “serious muscle weakness”.

(a)  

24.

Slow or suppress the immune system responses in an attempt to stop the inflammation involve in the autoimmune attack.

(a)  

25.

Involve in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation.

(a)  

26.

Decreases the number of circulating lymphocytes.

(a)  

27.

Used to treat certain cancer and rheumatoid arthritis.

(a)  

28.

A class of diseases in which a cell, or a group of cells display uncontrolled growth.

(a)  

29.

Vaccine mixed with strep and staph bacteria which produces Erysipelas which causes the malignant tumor to disappear.

(a)  

30.

was considered as the Father of Immunotherapy

(a)  

31.

Use to treat bladder cancer (BCG)

(a)  

32.

Interact with cells in order to regulate the body’s response and to trigger disease and infections.

(a)  

33.

Use to treat kidney cancer

(a)  

34.

Use to stimulate the body’s immune system to fight some types of cancer.

(a)  

35.

These are cytotoxic weapons that seek and kill only the cancer cells.

(a)  

36.

used against breast cancer

(a)  

37.

chronic use of drug, alcohol, or similar substances

(a)  

38.

Major obstacles in transplantation. Incompatibility with the transplanted organ. The organs are called allograft.

(a)  

39.

The production and emission of light

by a living organism.

(a)  

40.

Type of medical test that identifies

changes in genes, chromosomes, or proteins.

(a)  

41.

A method of identifying genetic material.

(a)  

42.

Any of a class of natural or synthetic substances

composed of very large molecules.

(a)  

43.

used to signify an enzyme

(a)  

44.

Proteins that help speed up

metabolism, or the chemical reactions in

our bodies.

(a)  

45.

(a)   of a DNA fragment to millions and billions copy of the genetic material.

46.

Pair of primers hybridizes with the sample DNA and defines

the region that will be amplified, resulting in millions and millions of

copies in a very short timeframe.

(a)  

47.

THE DOUBLE-STRANDED TEMPLATE DNA IS

HEATED BY 94 TO 95 DEGREE CELCIUS TO SEPARATE IT INTO TWO

SINGLE STRANDS.

(a)  

48.

THE TEMPERATURE IS LOWERED BY 50 TO 65 DEGREE

CELCIUS TO ENABLE THE DNA PRIMERS TO ATTACH TO THE

TEMPLATE DNA.

(a)  

49.

THE TEMPERATURE IS RAISED NY 72 DEGREE CELCIUS

AND THE NEW STRAND OF DNA IS MADE BY THE TAQ POLYMERASE

ENZYME.

(a)  

50.

It automates the repetitive step of

amplifying specific DNA sequences.

(a)  

51.

Application of Polymerase Chain Reaction

(a)  

52.

Used when you are investigating a gene and have no

easy way to determine if the gene is being expressed.

(a)  

53.

Types of reporter genes

(a)  

54.

Fluoresce based reporter

(a)  

55.

Enzyme based colorimetric reporter.

(a)  

56.

Bioluminescence based reporter.

(a)  

57.

Cells-comes from a Greek word

“Soma” meaning body.

(a)  

58.

cells forming the body of

organisms and are known as diploids

(a)  

59.

Biological cells that give rise to

the formation of gametes(sperm and egg

cell) and are known as haploids.

(a)  

60.

Highly specialized

cells and are fully developed.

(a)  

61.

Primitive and do

not perform high level function and they

have no specialized functions.

(a)  

62.

Undifferentiated cells that can

be specialized. They have the ability to

reproduce indefinitely.

(a)  

63.

Derived from adult tissues,

from umbilical cords and fetal tissues.

(a)  

64.

Derived from the

early stage of embryo.

(a)  

65.

Cells from which

all other cells with specialized functions are

generated.

(a)  

66.

Types of stem cells

(a)  

67.

mostly used to produce cattle

(a)  

68.

What is the first successful

cloned animal

(a)  

69.

Decreed that the creation of a human embryonic stem cell line is a felony.

(a)  

70.

Are single-celled organisms,

commonly used as host cells for making copies

of DNA in the lab because they are easy to

grow in large numbers. Their cellular

machinery naturally carries out DNA

replication and protein synthesis.

(a)  

71.

is a DNA-joining enzyme

(a)  

72.

Any whole food whose genetic

material has been altered using genetic

engineering techniques.

(a)  

73.

Joining two DNA fragments via

a ligase-catalyzed reaction.

(a)  

74.

A small circular DNA molecule

found in bacteria and some other

microscopic organisms.

(a)  

75.

The

term used to describe the combination of

two DNA strands that are constructed

artificially.

(a)  

76.

A protein produced

by bacteria that cleaves DNA at specific

sites along the molecule.

(a)  

77.

The process by which

exogenous DNA is transferred into the

host cell.

(a)  

78.

The use of high-

voltage electric shocks to introduce

DNA into cells.

(a)  

79.

The bacterial cells are incubated with

recombinant DNA on ice, followed by placing them

briefly at 42o C and then putting it back on ice.

(a)  

80.

A DNA molecule (often plasmid or virus) that is

used as a vehicle to carry a particular DNA segment into a

host cell as part of recombinant DNA technique.

(a)  

81.

Extra-chromosomal, self-replicating,

double-stranded circular DNA molecules found in

various bacteria and in some yeast.

(a)  

82.

Viruses that infect bacterial

cells by injecting their DNA into these cells.

(a)  

83.

Fusion of DNA molecules

from two distinct species.

(a)  

84.

STEPS OF GENETIC

RECOMBINATION TECHNOLOGY

(a)  

85.

IMPORTANCE OF RECOMBINANT

DNA TECHNOLOGY

(a)