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Immune System

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Innate immunity.....

a)

is activated immediately upon infection

b)

depends on an infected animal's previous exposure to the same pathogen

c)

is based on recognition of antigens that are specific to different pathogens

d)

is found only in vertebrate animals

2.

The most inclusive set of symptoms of inflammation is ________.

a)

heat, pain, and redness

b)

pain and whitening of the surrounding tissue

c)

swelling and pain

d)

swelling, heat, redness, and pain

3.

The cells/signaling molecules involved in the initiation of the inflammatory response are ___, while cells/signaling molecules that initiate dilation of blood vessels are ___.

a)

phagocytes and lysozymes

b)

macrophages/chemokines; mast cells/histamines

c)

dendritic cells/interferons; mast cells/lysozymes

d)

mast cells/ histamines; phagocytes

4.

The results shown in the accompanying graph support the hypothesis that ________.

a)

Toll protein is necessary for protection from death by fungal infection

b)

after fungal infection, wild-type flies die more rapidly than mutants lacking the Toll protein

c)

flies lacking the Toll protein die within one day of a fungal infection

d)

Toll proteins have a delayed affect in killing flies

5.

Antigens are ____.

a)

immunoglobulins.

b)

used by the immune system to neutralize foreign objects.

c)

foreign molecules that can initiate an immune response.

d)

produced by white blood cells.

6.

The immune response that is rapid but generic is called ____.

a)

acquired

b)

adaptive

c)

individual

d)

innate

7.

Adaptive immunity is based upon ____.

a)

traits common to groups of pathogens.

b)

antigen-specific recognition.

c)

maternal provision of antibodies to offspring.

d)

plants being exposed to new pathogens.

8.

A person who took a drug that destroys the thymus would most likely ___.

a)

lack class I MHC molecules on cell surfaces

b)

be unable to genetically rearrange antigen receptors

c)

be unable to differentiate and mature T cells

d)

lack innate immunity

9.

The ability of one person to produce over a million different antibody molecules does not require over a million different genes; rather, this wide range of antibody production is due to ________.

a)

increased rate of mutation in the RNA molecules

b)

genetic DNA recombination

c)

alternative splicing of exons after transcription

d)

rearrangements of cytosolic proteins in the thymus cells

10.

The activation of helper T cells is likely ________.

a)

when an antigen is displayed by a dendritic cell

b)

when a cytotoxic T cell releases cytokines

c)

when natural killer cells come in contact with a tumor cell

d)

in the bone marrow during the self-tolerance test

11.

Arrange these components in the correct sequence of the mammalian immune system as it first responds to a pathogen.

I.    Pathogen is destroyed.

II.  Lymphocytes secrete antibodies.

III. Antigens from the pathogen bind to receptors on lymphocytes.

IV. Lymphocytes specific to antigens from the pathogen become numerous.

V.  Only memory cells remain.

a)

III → II → I → V → IV

b)

III → IV → II → I → V

c)

II → I → IV → III → V

d)

I → III → II → IV → V

12.

Which statement best describes the difference in responses of effector B cells (or plasma cells) and cytotoxic T cells?

a)

Effector B cells secrete antibodies that are specific for a certain pathogen; cytotoxic T cells kill pathogen-infected host cells.

b)

Effector B cells kill pathogens directly; cytotoxic T cells kill host cells.

c)

Effector B cells confer active immunity; cytotoxic T cells confer passive immunity.

d)

Effector B cells carry out the cell-mediated response; cytotoxic T cells carry out the humoral response.

13.

You and a friend were in line for a movie when you noticed the woman in front of you sneezing and coughing. Both of you were equally exposed to the woman's virus, but over the next few days, only your friend acquired flu-like symptoms and was ill for almost a week before recovering. Which one of the following is a logical explanation for this?

a)

Your friend had an autoimmune disorder.

b)

Your friend had allergies.

c)

Your friend had antibodies to that virus.

d)

You had an adaptive immunity to that virus.

14.

When you are injured, blood platelets release signals to activate more platelets. The new platelets then activate others. This is known as ___.

a)

a positive feedback loop

b)

a negative feedback loop

c)

an immune malfunction

d)

uncommon in animals

15.

All of the following are parts of the immune system except _____.

a)

skin

b)

bladder

c)

thymus

d)

spleen

e)

bone marrow