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Genetics & Genetic Engineering

Total questions: 80

Worksheet time: 1hrs 8mins

Name
Class
Date
1.
A genome is
a)
part of a chromosome
b)
a gene inserted into a chromosome of bacteria
c)
a sequence of units in a short segment of DNA
d)
the complete sequence of an organism’s DNA  
2.
Freckles (F) are dominant over nonfreckles.   What is the phenotype of individual #3
a)
Ff
b)
ff
c)
freckles 
d)
nonfreckles 
3.

Identify what type of mutation occurred:


Normal = ATA - CCC - ATC - GTC - ACT

Mutated = ATA - CCC - ACC - GTC - ACT

a)

Silent

b)

Substitution

c)

Insertion

d)

Deletion

4.

Identify what kind of mutation occurred:


AAA - TTC - CCG - GGG

AAA - TTT - CCC - GGG - G

a)

Nonsense

b)

Point Substitution

c)

Insertion

d)

Deletion

5.

A substitution mutation is what type of mutation?

a)

Point

b)

Frameshift

c)

Silent

6.

A mutation is any change in ____ to an organism.

a)

Gametic

b)

Personality

c)

DNA base sequence

d)

Cells

7.

What type of mutation occurs when a single nucleotide is substituted for another?

a)

Silent

b)

Missense

c)

Point Mutation

d)

Frameshift mutation

8.

Insertions and deletions are what type of mutation?

a)

Strong mutations

b)

Frameshift mutations

c)

Point Mutations

d)

Nonsense mutations

9.

Which answer shows a gene sequence that has undergone a substitution mutation. The normal sequence is ACTTTTGCAACTTCA

a)

ACTTTTTGCAACTTCA

b)

ACTTTGCAACTTCA

c)

ACTTTTCCAACTTCA

d)

ACTTTTGCAACTTCA

10.

Which type of mutation is normally more severe because they affect more than one codon?

a)

Point Mutations

b)

Substitution mutations

c)

mutations where A's are replaced with T's

d)

Frameshift Mutaitons

11.

What kind of mutation is shown?

a)

Point mutation

b)

deletion

c)

insertion

d)

substitution/

12.
What mutation has occurred here? 
T-G-A-C-C-A
T-G-A-G-C-A
a)
Substitution
b)
Deletion
c)
Insertion
d)
Frameshift 
13.
Normal-
AGA-TTC-ATA-GCG
Mutant-
AGA-TTC-AAT-AGC-G
a)
deletion frameshift
b)
insertion frameshift
c)
substitution
d)
nonsense
14.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

15.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

16.

The chromosomal mutation shown in the image is a

a)

deletion

b)

duplication

c)

inversion

d)

translocation

17.
Identify the mutation in the picture.
a)
Inversion
b)
Deletion
c)
Duplication
d)
Translocation
18.
Identify the mutation in the picture.
a)
Inversion
b)
Duplication
c)
Deletion
d)
Translocation
19.
What type of chromosomal mutation has occurred?
a)
substitution
b)
insertion
c)
deletion
d)
nondisjunction
20.

Duplication

a)

A

b)

B

c)

C

d)

D

e)

E

21.

Inversion

a)

A

b)

B

c)

C

d)

D

e)

E

22.

When the rough strain (R strain) was injected, did the mice live or die?

a)

Live

b)

Die

c)

Some lived and some died

d)

None of the above

23.

When the smooth strain (S strain) was injected, did the mice live or die?

a)

Live

b)

Die

c)

Some lived and some died

d)

None of the above

24.

what bacteria did Griffith use in his experiment?

a)

e. coli

b)

pneumonia

c)

cholera

d)

strep

25.

Which strain causes mice to get sick and die?

a)

R strain

b)

S strain

c)

heat killed S strain

26.

Which strain has a rough coat?

a)

R strain

b)

S strain

27.

What happened to mice when live R strain was mixed with heat killed S strain?

a)

They lived

b)

They died

c)

The mice were changed

28.

Why did mice die with R strain was mixed with heat killed S strain?

a)

the heat killed S strain took in the DNA of the R strain to become live S again

b)

the R strain took in the DNA of the heat killed S to become live S

c)

the live S strain took in the DNA of the R strain and became live R

29.

The change in the characteristics/traits of an organism resulting from the uptake of foreign DNA

a)

transconfiguration

b)

transformation

c)

transcription

d)

translation

30.

Using the image what happened to the mice labeled X and Z?

a)

Both X and Z died

b)

Both X and Z lived

c)

X died and Z lived

d)

X lived and Z died

31.
Which of the following combinations of sex chromosomes represent a female?
a)
XY
b)
XXY
c)
XX
32.
Are all mutations bad?
a)
Yes
b)
No
33.
The following karyotype illustrates an example of which syndrome?
a)
Turner's Syndrome
b)
Klienfelter's Syndrome
c)
Edward's Syndrome
d)
Down Syndrome
34.
Trisomy 21 means you have what?
a)
Three copies of chromosome 21
b)
Twenty one copies of chromosome 3
c)
Three omies and 21 means
d)
Two copies of chromosome 21
35.
What type of karyotype is shown here?
a)
Male with Turner Syndrome
b)
Male with Klinefelter Syndrome
c)
Female with Down Syndrome
d)
Female with Klinefelter Syndrome
36.
What's the gender and disorder?
a)
Male - Downs Syndrome
b)
Female - Downs Syndrome
c)
Male - Turner Syndrome
d)
Female - Turner Syndrome
37.
What are chromosomes 1-22 called?
a)
Autosomes
b)
Sex Chromosomes
c)
Chromotids
d)
Xenosomes
38.
The genetic makeup of an organism or what represents the letters in a Dihybrid Cross
a)
allele
b)
genotype
c)
phenotype
d)
karyotype
39.
What describes the physical appearance of a trait?
a)
allele
b)
genotype
c)
phenotype
d)
karyotype
40.
If alleles look like Aa in a genotype it is said to be
a)
homozygous
b)
heterozygous
c)
incomplete dominant
d)
codominant 
41.
If alleles look like AA in a genotype it is said to be
a)
homozygous
b)
heterozygous
c)
incomplete dominant
d)
codominant
42.
Trait will always show up in an organism if the allele is present
a)
recessive
b)
dominant
c)
incomplete dominant
d)
codominant
43.
This all is covered up when a dominant allele is present
a)
recessive
b)
dominant
c)
incomplete dominance
d)
co-dominant
44.
If two heterozygous tall plants are crossed, and tall is dominant. What would be your expected phenotypes?
a)
100% tall
b)
75% tall, 25%short
c)
50% tall, 50%short
d)
25% tall, 75% short
45.
Unattached earlobes (E) is dominant. Attached earlobes (e) is recessive. A woman with the genotype (Ee) and a man with the genotype (ee) have a child. What is the probability that the child is heterozygous?
a)
0%
b)
25%
c)
50%
d)
75%
46.
If the allele for gray fur (G) is dominant to the allele for white fur (g) in mice, What will be the ratio if you cross a heterozygous gray mouse with a white mouse?
a)
3GG : 0Gg : 1gg
b)
2GG : 1Gg : 1gg
c)
1GG : 2Gg : 1gg
d)
0GG : 2Gg : 2gg
47.
Tomato plants usually have hairy stems. Hairless stems are present in tomato plants that are homozygous recessive for this trait. If the stem characteristics are determined by a single gene, what is the expected outcome of crossing two tomato plants that are heterozygous for hairy stems?
a)
100% hairless stems
b)
100% hairy stems
c)
50% hairy stems : 50% hairless stems
d)
75% hairy stems : 25% hairless stems
48.
What is going to be the genotype that is missing?
a)
AABb
b)
AABB
c)
AAbb
d)
aaBB
49.
If human body cells have 46 chromosomes, how many chromosomes will be in gamete cells after meiosis?
a)
92
b)
46
c)
23
d)
12
50.

The color purple (P) is dominant to the color white (p). According to the Punnett Square, what is the probability of an offspring being white?

a)

0%

b)

25%

c)

50%

d)

75%

51.

The color purple (P) is dominant to the color white (p). According to the Punnett Square, what is the ratio of phenotypes?

a)

3 Purple: 1 White

b)

2 Purple: 2 White

c)

1 Purple: 3 White

d)

4 Purple

52.

Which of the following are the genotype?

a)

Tt, Ww

b)

Red, White

c)

Red, Rr

53.

In a genotype, what does the lower case letter represent?

a)

Recessive

b)

Dominant

54.
A heterozygous yellow pea plant's genotype would be:
a)
YY
b)
yy
c)
Yy
d)
Yg
55.
If T=Tall & t=short, what is the genotypic ratio?
a)
1:3
b)
3:1
c)
1:2:1
d)
2:2
56.
The passing of traits from parent to offspring 
a)
Heredity 
b)
Genetics 
c)
Hybrid 
d)
Probability 
57.
Who was the father of genetics 
a)
Sagan 
b)
Issac Newton 
c)
Gregor Mendel 
d)
C.jenkins 
58.

Squidward has light blue skin, and his genotype for this trait is Bb. Which of the following would describe Squidward?

a)

Purebred

b)

Hybrid

c)

Homozygous

d)

Sex-linked

59.
An allele whose trait only shows up when no dominant allele is present.
a)
hidden allele
b)
dominant allele
c)
recessive allele
d)
present allele
60.
An offspring will receive how many alleles from each parent to determine a specific trait?
a)
one
b)
two
c)
three
d)
five
61.
A calico cat shows both the traits for orange fur and black fur. What kind of allele expression is this?
a)
Incomplete Dominance
b)
Co dominance
c)
Independent assortment
d)
Recessive inheritance
62.
How are Incomplete Dominance and Co Dominance different than a normal Mendelian cross?
a)
There is no difference
b)
The heterozygous genotype has a unique phenotype
c)
There is no heterozygous genotype
d)
There is only one phenotype regardless of genotype.
63.
A roan cow shows co-dominance in fur color (orange and white). What is the phenotype ratio expected if a roan cow and a roan steer mate together?
a)
4: Orange and White
b)
1: Orange : 1 White
c)
2 Orange: 2 Orange and White: 0 White
d)
1: Orange: 2 Orange and White: 1 White
64.
A red flowered plant (RR) breeds with a White flowered plant (WW). The gene for petal color in these plants expresses incomplete dominance.  What percentage of the offspring will have pink (RW) flowers?
a)
0%
b)
25%
c)
50%
d)
100%
65.
This type of inheritance pattern is a MIXTURE of both traits.
a)
incomplete dominance
b)
co-dominance
c)
complete dominance
d)
recessive pattern
66.
This type of inheritance pattern shows BOTH traits in possible offspring
a)
complete dominance
b)
incomplete dominance
c)
co-dominance
d)
dominant pattern
67.

A woman with curly hair and a man with straight hair produced a child with wavy hair:

a)

Incomplete dominance

b)

Codominance

c)

Complete dominance

68.

A long-haired female rabbit and a short-haired male rabbit produced this offspring with a medium-length coat:

a)

Incomplete dominance

b)

Codominance

c)

Complete dominance

69.

If the offsprings have the blood groups O and A the genotype of parents would be

a)

IAIA and IAi

b)

IA i and ii

c)

IAIA and IAIA

d)

IA i and IBi

70.

What are the blood types of the possible children that a woman (type O) and man (type AB) can have?

a)

O and AB

b)

O and A

c)

O and B

d)

A and B

71.

There are multiple alleles for the ABO blood group. Why are only two of these alleles present in any one individual?

a)

Each parent contributes only one allele for the ABO blood group to the offspring.

b)

There are not enough nucleotides in a red blood cell to produce a third allele.

c)

Each allele in the ABO group must be dominant or recessive

d)

Blood group alleles are not segregated during meiosis.

72.

A personal with type AB blood has which genotype?

a)

type A

b)

AA

c)

IAIA

d)

IAIB

73.

A man with type O blood is accused of being the father of a type B baby. The mother is type A. Could this man be the father?

a)

Yes

b)

No

74.

If a person has type B blood, the phenotype is B. What can the genotype be?

a)

IBIB or IBi

b)

IAIA or IAi

c)

IAIB

d)

ii

75.

If a person has type A blood, the phenotype is A. What can the genotype be?

a)

IBIB or IBi

b)

IAIA or IAi

c)

IAIB

d)

ii

76.
What goes in box 1
a)
AABb
b)
AABB
c)
aabb
d)
AaBb
77.
What genotype is missing from this Punnett Square?
a)
RrYy
b)
RRYY
c)
rryy
d)
RrYY
78.
Based off this punnett square, what fraction of the offspring will have wrinkled, yellow seeds?
a)
9/16
b)
3/16
c)
1/16
d)
16/16
79.
Assume dad's gametes are on top, what is his genotype?
a)
AAPP
b)
AaPp
c)
aaPP
d)
Aapp
80.
Assume mom's gametes are on the left, what is her genotype?
a)
TTZz
b)
TtZz
c)
ttZZ
d)
TtZZ

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