The patient, a 6-year-old male, presents with a history of gradually worsening fatigue, pallor, and petechiae over the past month. His parents also report that he has experienced recurrent nosebleeds and easy bruising during this time. There is no history of fever, weight loss, or significant infections. Physical examination reveals pallor, petechiae over the extremities, and mild hepatosplenomegaly. Bone marrow biopsy reveals blast cells (Lymphoblasts). What is your diagnosis?

The patient, a 15-year-old female with Down syndrome, presents with a three-week history of persistent fever, fatigue, and easy bruising. She has also experienced intermittent bone pain. There is no history of significant infections, weight loss, or night sweats. Physical examination reveals pallor, petechiae, and mild hepatosplenomegaly. Smear shows leukocytosis with a predominance of myeloblasts with the presence of Auer Rods. What is your diagnosis?

What type of infectious agents are seen in cases of splenic damage?

BCR-ABL1 gene mutation is seen in what type of leukemia?

BCR-ABL1 gene mutation involves ___ and is referred to as the ___

The patient, a 63-year-old male, presents with a six-month history of progressively worsening bone pain, primarily affecting the lower back and ribs. He reports increasing fatigue and a history of recurrent respiratory and urinary tract infections during this period. There is no history of unintentional weight loss, night sweats, or recent travel. Physical examination reveals tenderness over the spine, and there is no palpable lymphadenopathy or organomegaly. Serum Protein Electrophoresis reveals presence of a monoclonal spike (M-spike) in the gamma globulin region.

• Serum protein electrophoresis reveals a prominent peak in the gamma globulin region and Bence Jones Proteins. X-ray reveal 'punched out lesions.' What is your diagnosis?

Which lymphoma carries a worse prognosis?

Burkitt Lymphoma involves translocation of the ___ gene and a latent infection of ___?

The patient, an 8-year-old African American male, was brought to the pediatric clinic with a one-month history of progressive swelling on the right side of his jaw. His parents also reported intermittent abdominal pain and increased fatigue over the same period. The patient had no recent history of infections, fever, or significant weight loss. Physical examination revealed a palpable right mandibular mass and mild hepatosplenomegaly. This patient's diagnosis is ___ and ___ would be seen on a lymph node biopsy:

The patient, a 28-year-old female, presented to our clinic with a chief complaint of a painless swelling in her neck, which she first noticed two months ago. The swelling progressively increased in size and was associated with intermittent night sweats and unintentional weight loss of 10 pounds over the past two months. She denied fever, fatigue, pruritus, or any other significant symptoms. Reed-Sternberg cells are seen on lymph node biopsy. What is your diagnosis?