Worksheetspatho B finals
Total questions: 46
Worksheet time: 26mins
Components of the blood vessel EXCEPT?
endothelial cells
mesothelial cells
smooth muscle cells
Affected during the aging process of arteries making them less compliant?
laminin
elastin
collagen
principal points of physiologic resistance to blood flow?
venules
arterioles
ideally suited for the exchange of diffusible substances between blood and tissues?
venules
arterioles
capillaries
Involved in the release of anticoagulant, antithrombotic, and fibrinolytic regulators in endothelial cells?
prostacycline
Von Willebrand factor
characterized by calcificantions of the medial walls of muscular arteries, typically starting along the internal eslastic membrane and are usually not clinically significant?
hyaline arteriosclerosis
atherosclerosis
Monckeberg medial sclerosis
Atherosclerosis can induced the formation of aneurysm through pressure or ischemic atrophy of what particular layer of the blood vessel wall??
intima
media
adventitia
What is the major structural component of the fibrous cap of atherosclerotic plaque which accounts for its mechanical strength and stability?
endothelial cells
esterified LDL
collagen
This pertains to ruptured wall of blood vessels with extravasation of blood into its surrounding extravascular connective tissue giving it a bulging hematoma on one side.
saccular aneurysm
false aneurysm
This form of vasculitis primarily affects older individuals and can involve the aorta and other large sized arteries causing intimal thickening with medial granulomatous inflammation, lymphocytic infiltrates, giant cell formation, with a negative serum ANCA
Churg-Strauss syndrome
giant cell arteritis
takayasu arteritis
A 22 year-old, male, heavy smoker came in due to severe lower extremity pain at the distribution of the tibial artery with claudication and ulcer formation. Blood vessel show a lumen occluded by a thrombus containing microabscesses and the vessel wall is infiltrated with leukocytes.
thromboangiitis obliterans
Behcet syndrome
This form of vasculitis presents with orogenital ulcers. Biopsy often shows neutrophilic infiltrates of the affected vessel which is needed for its diagnosis.
Churg-Strauss syndrome
Behcet syndrome
This form of primary vasculitis clinically presents with asthma and atopy. Biopsy will show eosinophilic infiltrates of the affected vessel.
Polyarteriris nodosa
Churg-Strauss syndrome
It can manifest with fever, conjunctival injection, mucosal erythema and cervical lymphadenopathy. Death may be due to myocardial infarction due to ruptured coronary artery aneurysm. Biopsy will show dense transmural inflammatory infiltrate and fibrinoid necrosis.
Wegener granulomatosis
Kawasaki disease
associated with PR3-ANCA
microscopic polyangitis
granulomatosis with polyangitis
most common type of hemangioma
cavernous hamengaioma
capillary hemangioma
most common cause of bacterial lymphangitis
Staphylococcus aureus
group A beta hemolytic streptococcus
cornerstone of the "response to injury" hypothesis of atherosclerosis
accumulation of lipoproteins mainly LDL and its oxidized form
endothelial injury
turns on atheroprotective genes and turn off inflammatory gene transcription
Kruppel-like factor-2
vascular endothelial growth factor
Defective synthesis of what type of collagen is the hallmark of the vascular form of Ehlers-Danlos syndrome?
collagen type 1
collagen type 2
collagen type 3
collagen type 4
Loeys-Dietz syndrome and Marfan syndrome has an abnormal signaling involving what growth factor
fibroblast growth factor
platelet derived growth factor
transforming growth factor beta
DeBakey classification involving the ascending aorta only
I
II
III
IV
AIDS-associated Kaposi Sarcoma is caused by
HIV
HHV 8
Warthin-finkeldey cells
mumps
measles
koplik spots
mumps
measles
cowdry type A
adenovirus
HSV
dewdrop on a rose petal
HSV
VZV
exhibit gigantism of the entire cell and its nucleus, which typically contains a large inclusion surrounded by a clear halo (“owl’s eye”)
VZV
CMV
HSV
RSV
cause necrotizing pneumonia that is distributed through the terminal airways in a fleur-de-lis pattern
C. diphtheriae
S. pneumoniae
L. monocytogenes
Pseudomonas spp.
chancroid
Treponema pallidum
Haemophilus ducreyi
Ghon complex
primary tb
secondary tb
the most frequent presentation of extrapulmonary tuberculosis
scrofula
Pott disease
Intestinal TB usually affects
duodenum
ileum
jejunum
intact cell mediated immunity
tuberculoid leprosy
lepromatous leprosy
Greater TH2 response
tuberculoid leprosy
lepromatous leprosy
aortitis and gummas
primary syphilis
secondary syphilis
tertiary syphilis
Gas gangrene
C. perfringens
C. difficile
most commonly sexually transmitted bacterial disease
N. gonorrhea
C. trachomatis
Non-septate hyphae branching at right angle causing hemorrhagic pneumonia
mucor
aspergillus
Durck granuloma
Babesia
plasmodium
kala-azar Leishmania
cutaneous
visceral
Dilated cardiomyopathy, megaesophagus, and megacolon
Trichinella spiralis
Trypanosoma cruzi
Meyers Kouwenaar bodies
Trypanosoma brucei
Strongyloides stercoralis
Brugia malayi
Onchocerca volvulus
Mazzotti reaction
Wuchereria bancrofti
Onchocerca volvulus
Hydatid cyst
Echinococcus granulosus
Taenia solium
bladder squamous cell carcinoma
Schistosoma japonicum
Schistosoma haematobium
