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patho B finals

Total questions: 46

Worksheet time: 26mins

Name
Class
Date
1.

Components of the blood vessel EXCEPT?

a)

endothelial cells

b)

mesothelial cells

c)

smooth muscle cells

2.

Affected during the aging process of arteries making them less compliant?

a)

laminin

b)

elastin

c)

collagen

3.

principal points of physiologic resistance to blood flow?

a)

venules

b)

arterioles

4.

ideally suited for the exchange of diffusible substances between blood and tissues?

a)

venules

b)

arterioles

c)

capillaries

5.

Involved in the release of anticoagulant, antithrombotic, and fibrinolytic regulators in endothelial cells?

a)

prostacycline

b)

Von Willebrand factor

6.

characterized by calcificantions of the medial walls of muscular arteries, typically starting along the internal eslastic membrane and are usually not clinically significant?

a)

hyaline arteriosclerosis

b)

atherosclerosis

c)

Monckeberg medial sclerosis

7.

Atherosclerosis can induced the formation of aneurysm through pressure or ischemic atrophy of what particular layer of the blood vessel wall??

a)

intima

b)

media

c)

adventitia

8.

What is the major structural component of the fibrous cap of atherosclerotic plaque which accounts for its mechanical strength and stability?

a)

endothelial cells

b)

esterified LDL

c)

collagen

9.

This pertains to ruptured wall of blood vessels with extravasation of blood into its surrounding extravascular connective tissue giving it a bulging hematoma on one side.

a)

saccular aneurysm

b)

false aneurysm

10.

This form of vasculitis primarily affects older individuals and can involve the aorta and other large sized arteries causing intimal thickening with medial granulomatous inflammation, lymphocytic infiltrates, giant cell formation, with a negative serum ANCA

a)

Churg-Strauss syndrome

b)

giant cell arteritis

c)

takayasu arteritis

11.

A 22 year-old, male, heavy smoker came in due to severe lower extremity pain at the distribution of the tibial artery with claudication and ulcer formation. Blood vessel show a lumen occluded by a thrombus containing microabscesses and the vessel wall is infiltrated with leukocytes.

a)

thromboangiitis obliterans

b)

Behcet syndrome

12.

This form of vasculitis presents with orogenital ulcers. Biopsy often shows neutrophilic infiltrates of the affected vessel which is needed for its diagnosis.

a)

Churg-Strauss syndrome

b)

Behcet syndrome

13.

This form of primary vasculitis clinically presents with asthma and atopy. Biopsy will show eosinophilic infiltrates of the affected vessel.

a)

Polyarteriris nodosa

b)

Churg-Strauss syndrome

14.

It can manifest with fever, conjunctival injection, mucosal erythema and cervical lymphadenopathy. Death may be due to myocardial infarction due to ruptured coronary artery aneurysm. Biopsy will show dense transmural inflammatory infiltrate and fibrinoid necrosis.

a)

Wegener granulomatosis

b)

Kawasaki disease

15.

associated with PR3-ANCA

a)

microscopic polyangitis

b)

granulomatosis with polyangitis

16.

most common type of hemangioma

a)

cavernous hamengaioma

b)

capillary hemangioma

17.

most common cause of bacterial lymphangitis

a)

Staphylococcus aureus

b)

group A beta hemolytic streptococcus

18.

cornerstone of the "response to injury" hypothesis of atherosclerosis

a)

accumulation of lipoproteins mainly LDL and its oxidized form

b)

endothelial injury

19.

turns on atheroprotective genes and turn off inflammatory gene transcription

a)

Kruppel-like factor-2

b)

vascular endothelial growth factor

20.

Defective synthesis of what type of collagen is the hallmark of the vascular form of Ehlers-Danlos syndrome?

a)

collagen type 1

b)

collagen type 2

c)

collagen type 3

d)

collagen type 4

21.

Loeys-Dietz syndrome and Marfan syndrome has an abnormal signaling involving what growth factor

a)

fibroblast growth factor

b)

platelet derived growth factor

c)

transforming growth factor beta

22.

DeBakey classification involving the ascending aorta only

a)

I

b)

II

c)

III

d)

IV

23.

AIDS-associated Kaposi Sarcoma is caused by

a)

HIV

b)

HHV 8

24.

Warthin-finkeldey cells

a)

mumps

b)

measles

25.

koplik spots

a)

mumps

b)

measles

26.

cowdry type A

a)

adenovirus

b)

HSV

27.

dewdrop on a rose petal

a)

HSV

b)

VZV

28.

exhibit gigantism of the entire cell and its nucleus, which typically contains a large inclusion surrounded by a clear halo (“owl’s eye”)

a)

VZV

b)

CMV

c)

HSV

d)

RSV

29.

cause necrotizing pneumonia that is distributed through the terminal airways in a fleur-de-lis pattern


a)

C. diphtheriae

b)

S. pneumoniae

c)

L. monocytogenes

d)

Pseudomonas spp.

30.

chancroid

a)

Treponema pallidum

b)

Haemophilus ducreyi

31.

Ghon complex

a)

primary tb

b)

secondary tb

32.

the most frequent presentation of extrapulmonary tuberculosis

a)

scrofula

b)

Pott disease

33.

Intestinal TB usually affects

a)

duodenum

b)

ileum

c)

jejunum

34.

intact cell mediated immunity

a)

tuberculoid leprosy

b)

lepromatous leprosy

35.

Greater TH2 response

a)

tuberculoid leprosy

b)

lepromatous leprosy

36.

aortitis and gummas

a)

primary syphilis

b)

secondary syphilis

c)

tertiary syphilis

37.

Gas gangrene

a)

C. perfringens

b)

C. difficile

38.

most commonly sexually transmitted bacterial disease

a)

N. gonorrhea

b)

C. trachomatis

39.

Non-septate hyphae branching at right angle causing hemorrhagic pneumonia

a)

mucor

b)

aspergillus

40.

Durck granuloma

a)

Babesia

b)

plasmodium

41.

kala-azar Leishmania

a)

cutaneous

b)

visceral

42.

Dilated cardiomyopathy, megaesophagus, and megacolon

a)

Trichinella spiralis

b)

Trypanosoma cruzi

43.

Meyers Kouwenaar bodies

a)

Trypanosoma brucei

b)

Strongyloides stercoralis

c)

Brugia malayi

d)

Onchocerca volvulus

44.

Mazzotti reaction

a)

Wuchereria bancrofti

b)

Onchocerca volvulus

45.

Hydatid cyst

a)

Echinococcus granulosus

b)

Taenia solium

46.

bladder squamous cell carcinoma

a)

Schistosoma japonicum

b)

Schistosoma haematobium