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CHEM 465 Glycogenolysis and Glycogenesis

Total questions: 33

Worksheet time: 24mins

Name
Class
Date
1.

What three enzymes are Glycogenolysis?

a)

Glycogen Phosphorylase

b)

Glycogen Debranching Enzyme

c)

Phospho-glucomutase

d)

UDG-Glucose Pyrophoylase

e)

Glycogen Synthase

2.

What three enzymes are Glycogenesis?

a)

Glycogen Phosphorylase

b)

Amylo to Transglycosylase

c)

Phospho-glucomutase

d)

UDG-Glucose Pyrophoylase

e)

Glycogen Synthase

3.

Where Glycogenolysis occurs

(a)  

4.

Where is glycogen mainly stored?

a)

Liver Tissue

b)

Skeletal Muscles

c)

Bone Tissue

d)

Gut Tissue

5.

The first enzyme in Glycogenolysis

(a)  

6.

Where does the glucose go after ___ enzyme occurs?

a)

Enzyme: Glycogen phosphorylase

Goes to Glycolysis

b)

Enzyme: UDG-Glucose Pyrophosphorylase

Goes to Gluconeogenesis

c)

Enzyme: UDG-Glucose Pyrophosphorylase

Goes to Glycolysis

d)

Enzyme: Glycogen phosphorylase

Goes to Glucoenogenesis

e)

Enzyme: Glycogen Synthase

Goes to the next step in glycogenolysis

7.

This element measures the Glucose in Glycogenolysis by oxidizind the glucose molecule

a)

Copper

b)

Magnesium

c)

Zinc

d)

Phosphorus

8.

Glycogen Phosphorylase contains (a)   for Pi Transfer

9.

What is true?

i. The Oxidizing of glucose molecule is the Reducing End

ii. The PLP Attacks the Reducing End of the Glycogen molecule

a)

i. only

b)

ii. only

c)

both i. and ii.

d)

neither i. and ii.

10.

PLP attacks the ___ ends of Glycogen.

Also indicate if the end is the oxidized or reduced form of glucose

a)

Non reducing ends of glucose

The Glucose is reduced

b)

The non reducing ends of glucose The glucose is oxidized

c)

The reducing ends of glucose

The glucose is reduced

d)

The reducing ends of glucose

The glucose is oxidized

11.

What is the coenzyme involved in the Glycogen Phosphorylase?

a)

PLP

b)

NADH

c)

TPP

d)

FADH

12.

What carbon on the glucose molecule indicates that the glucose is reduced or not?

a)

Carbon 1

b)

Carbon 4

c)

Carbon 6

d)

Carbon 3

13.

The type of linkage on glycogen is (a)   #-># Linkage

14.

Is the reaction using the enzyme Glycogen Phosphorylase a favorable or non-favorable reaction?

a)

Favorable

b)

Non-Favorable

c)

Its just exergonic

d)

The ΔG is irrelevant

15.

The enzyme Glycogen Phosphorylase changes what linkages?

____ linkage -> ____ linkage

a)

Ether, Ester

b)

Ester, Ether

c)

Ester, Anhydride

d)

Ether, Anhydride

16.

How is PLP attached to its enzyme?

a)

Schiff's Base

b)

Non-covalently Attached

c)

Uses an Ester

d)

Uses an Ether

17.

The Amino Acid involved in Schiff's Base

(a)  

18.

Schiff's Base used what two functional groups?

a)

Aldehyde

b)

Amino

c)

Carboxylic Acid

d)

Ester

e)

Carboxyl

19.

When the Glycogen Phosphorylase reaches a branching point 4-5 residues away, this enzyme is used

(a)  

20.

The Glycogen Debranching enzyme ____ the ___ Carbon

a)

Hydrolyzes

Sixth

b)

Decarboxylizes

Sixth

c)

Hydrolyzes

Fourth

d)

Decraboylize

Fourth

21.

How the debranching enzyme does its job

a)

Glycogen Phosphorylase reaches to a stopping point

b)

The use of transferase of breaking of the enzyme leaving a α1-6 glucose attached

c)

Glucosidase moves the chain of glucoses to another non-reducing end

d)

Glycogen phosphorylase continues its job

1)
2)
3)
4)
22.

What is the product of Glycogen Phosphorylase?

a)

Glucose-1-P

b)

Fructose

c)

Glucose with nothing attached to it

d)

Glucose-6-P

23.

Phosphoglucomutase involves what amino acid residue?

(a)  

24.

Why does phosphoglucomutase need to occur?

a)

Because Glucose needs to be converted into Glucose-1-Phosphate For Glycolysis to occur

b)

Because Glucose need to be converted into Glucose-1-Phosphate for Glycogenesis to occur

c)

Because Glucose need to be converted into Glycogen once again to go through glycolysis

25.

Glucose 6-Phosphate in the (a)   can directly get into Glycolysis

26.

Where does the glycogen breakdown occur when needed to raise blood glucose levels?

(a)  

27.

In the liver, the glucose 6-phosphate goes into the blood by which organelle?

a)

The ER

b)

The cytosol

c)

The mitochondria

d)

The Lysosomes

28.

The transporter name to deliver Glucose-6-Phosphate into the blood

(a)  

29.

What tissues would NOT have glucose 6-phosphatase?

a)

Muscle Tissue

b)

Adipose Tissue

c)

Skeletal Tissue

d)

Liver Tissue

30.

Why can't Glucose 6-Phosphate escape the cell?

a)

The charge of the molecule

b)

The size of the molecule

c)

There is a phosphate on the molecule

31.

What is the first enzyme in glycogenesis?

a)

UDG-Glucose Pyrophosphorylase

b)

Glycogen Synthase

c)

Amylo to transglycosylase

d)

Glycogen Phosphorylase

32.

The process of creating a glycosidic bond

(a)  

33.

What is pyrophosphate made out of

a)

2 phosphoryl group

b)

A phosphoryl group

c)

An anhydride and a phosphoryl group

d)

An ester and a phosphoryl group